Peptides

Pyr-Arg-Thr-Lys-Arg-AMC TFA also called pERTKR-AMC, is a pentapeptide fluorescent substrate containing AMC (7-amino-4-methylcoumarin).

QL9 (QLSPFPFDL) TFA is a high-affinity allogeneic antigen targeting the 2C T cell receptor (TCR).

S12 is a mutation in the RAS peptide where Gly (G) is replaced by Ser (S12). The peptide sequence is KLVVVGASGVGKS.

SEB Domain (152-161) TFA refers to the amino acids 152-161 of the structure domain B of Staphylococcal enterotoxin B (SEB), which is a toxin produced by Staphylococcus aureus. SEB Domain (152-161) TFA is highly conserved and can inhibit the cellular uptake of various staphylococcal enterotoxins, including SEA, SEE, and TSST-1.

Selcopintide (Cpne7-DP) acetate is a synthetic peptide composed of 10 amino acid residues corresponding to the 344-353 fragment of hCPNE7 protein. Selcopintide acetate reproduces the in vitro effects of CPNE7 by upregulating odontoblast marker genes, DSPP and nestin. Selcopintide acetate promotes dentin regeneration in teeth with varying degrees of dentin defects, resulting in regenerated hard tissue that exhibits characteristics similar to natural dentin.

Spinorphin TFA is an inhibitor of brain non-peptide peptidases. Spinorphin inhibits aminopeptidase, dipeptidyl peptidase III, angiotensin-converting enzyme and brain non-peptide enzymes. Spinorphin can be used for research on pain relief.

SV40 T-Ag-derived NLS peptide TFA is a nuclear localization signal peptide that can effectively transfer DNA labeled with this peptide into the cell nucleus.

Tat-beclin 1 scrambled TFA is a disordered portion and control of Tat-beclin 1, derived from a region of the autophagy protein beclin 1. Beclin 1 induces autophagy by binding to the human immunodeficiency virus HIV-1 Nef and interacting with the autophagy-negative regulator GAPR-1 (GLIPR2). Tat-beclin 1 can reduce the accumulation of polyglutamine-expanded protein aggregates and replication of various pathogens such as HIV. Tat-beclin 1 also reduces mortality in mice infected with chikungunya or West Nile viruses.

TAT-DEF-Elk-1 (TDE) is a cell-penetrating peptide inhibitor of Elk-1 that mimics and specifically interferes with the DEF domain of Elk-1 to achieve inhibition. TAT-DEF-Elk-1 prevents phosphorylation of Elk-1 and prevents nuclear translocation of Elk-1, without interfering with ERK or MSK1 activation. TAT-DEF-Elk-1 is a useful tool for analyzing the role of Elk-1 in neuronal plasticity development processes.

TCTDSTNCYKAT is an engineered variant peptide fragment of an antifreeze protein (AFP).

Tyrosinase-related Protein 2 (TRP-2) (181-188) is a short peptide sequence of the TRP2 protein, which is the main epitope recognized by anti-B16 CTLs for TRP-2. Tyrosinase-related Protein 2 (TRP-2) (181-188) binds to MHC class I H2-Kb with identical binding motifs.

Alpha-casein (90-95) TFA is a peptide fragment of alpha-casein.

Delta-Sleep Inducing Peptide acetate is a neuropeptide that has antioxidant and anti-anxiety effects.

Bamadutide (SAR425899) is a potent dual glucagon-like peptide-1 receptor/glucagon receptor agonist.

3x DYKDDDDK Tag is a useful tool for investigating the function and localization of proteins whose antibodies (Abs) are not available.

Survodutide (BI 456906) is a potent, selective glucagon receptor/GLP-1 receptor (GCGR/GLP-1R) dual agonist with EC50s of 0.52 nM and 0.33 nM in CHO-K1 cells, respectively.

3X HA Tag is a bioactive peptide composed of the 9-amino-acid sequence YPYDVPDYA repeated 3 times.

Selank (Selanc) acetate is a synthetic peptide derived from tuftsin.

Nisotirotide (LY-3457263) is a PYY analog agonist studied in type 2 diabetes and obesity.

Myostatin inhibitory peptide 7 is a 23 amino acids peptide, which is derived from amino acids 21 to 43 of the mouse myostatin prodomain.

VPM-p15 is a peptide agonist optimized for the adhesion G protein-coupled receptor GPR64 (also known as ADGRG2 or HE6).

Ala-MPSD TFA is a control peptide for MPSD.

Myostatin inhibitory peptide 2 (compd 2) is a myostatin inhibitor with a Kd of 35.9 nM.

BDC2.5 mimotope is a potent antigen-mimicking peptide that can activate CD4+ T cell populations that have the same antigen recognition properties as BDC2.5 cells.