Pheophorbide a is a product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer. It has been reported to inhibit U87MG cells with an IC50 value of 2.8 µg/ml and demonstrates cytostatic activity specifically against glioblastoma cells without affecting normal cells. It also displays antiproliferative activity against melanoma, breast, and lung cancer cells in vitro at 100 µg/ml.
Pheophorbide a
Catalog No.: GC44629Purity:>90.00%Synonyms: 2Deacetyl2vinylbacteriopheophorbide
Pheophorbide a is a product of chlorophyll breakdown that has been used as a photosensitizer in photodynamic therapy for the treatment of cancer.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 15664-29-6
5mgIn Stock
$34.00
1
25mgIn Stock
$105.00
1
50mgIn Stock
$200.00
1
100mgIn Stock
$371.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 5mg | $34.00 | In Stock | 1 | |
| 25mg | $105.00 | In Stock | 1 | |
| 50mg | $200.00 | In Stock | 1 | |
| 100mg | $371.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>90.00%Appearance:A solid
Chemical Properties
CAS No.
15664-29-6
Synonyms
2Deacetyl2vinylbacteriopheophorbide
SMILES
O=C1[C@H](C(OC)=O)C2=C3N/C(C(C)=C31)=C\C(C(CC)=C/4C)=NC4=C/C5=C(C=C)C(C)=C(/C=C6[C@@H](C)[C@H](CCC(O)=O)C2=N/6)N5
Molecular Formula
C35H36N4O5
Molecular Weight
592.7
Solubility
DMF: 1 mg/ml,DMSO: 1 mg/ml,DMSO:PBS(pH 7.2) (1:3): 0.25 mg/ml
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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