PNU-103017 |
| Catalog No.GC32327 |
PNU-103017 is an HIV protease inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 166335-18-8
Sample solution is provided at 25 µL, 10mM.
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PNU-103017 is an HIV protease inhibitor.
PNU-103017 is a selective HIV aspartyl protease inhibitor under evaluation as a potential oral treatment of Acquired Immunodeficiency Diseases. PNU-103017 is a racemic mixture of two enantiomers, designated PNU-103264 (R-) and PNU-103265 (S-). The Cmax (P≤0.0349), Cmin (P≤0.0168), and Cav (P≤0.0118) are significantly higher for the (R)- than the (S)-enantiomer, showing enantioselective pharmacokinetics of PNU-103017 in the dog[1].
[1]. Williams MG, et al. Stereospecific determination of an HIV aspartyl protease inhibitor, PNU-103017, in rat, dog and human plasma using a Pirkle-concept high-performance liquid chromatographic column.
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