GLPBio

Pruvanserin

Catalog No.: GC72789Purity:>99.00%Synonyms: EMD 281014 free acid; LY 2422347
COASDSData Sheet
Pruvanserin (EMD 281014 free acid) is a selective 5-HT2A receptor antagonist.

Products are for research use only. Not for human use. We do not sell to patients.

Pruvanserin
Cas No.: 443144-26-1
5mgIn Stock
$126.00
1
10mgIn Stock
$203.00
1
25mgIn Stock
$423.00
1
Tel: (909) 407-4943 / (909) 689-7124Email: sales@glpbio.com

Citations

No citations are currently available for this product. Below are selected publications citing GlpBio products.
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    Nature
    641, 529–536 (2025)
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    632, 686–694 (2024)
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    618, 1017–1023 (2023)
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    Nature
    610, 366–372 (2022)
  • Cell cover
    Cell
    187(9):2288-2304 (2024)
  • Cell cover
    Cell
    183(7):1867-1883 (2020)
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    Science
    388(6745) (2025)
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    387(6739) (2025)
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    387(6734) (2025)
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    35, 97–116 (2025)
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    34, 683–706 (2024)
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    33, 273–287 (2023)
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    33, 546–561 (2023)
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    33, 904–922 (2023)
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    31, 1291–1307 (2021)

Description

Pruvanserin (EMD 281014 free acid) is a selective 5-HT2A receptor antagonist. Pruvanserin alleviates tactile allodynia in diabetic rats. Pruvanserin can also be used for research of insomnia.

References:
[1]. Abbas A, et al. Pimavanserin tartrate: a 5-HT2A inverse agonist with potential for treating various neuropsychiatric disorders. Expert Opin Pharmacother. 2008 Dec;9(18):3251-9.
[2]. Mixcoatl-Zecuatl T, et al. A spinal mechanism of action for duloxetine in a rat model of painful diabetic neuropat. Br J Pharmacol. 2011 Sep;164(1):159-69.

Product Documents

Purity:>99.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
443144-26-1
Synonyms
EMD 281014 free acid; LY 2422347
Molecular Formula
C22H21FN4O
Molecular Weight
376.43
Storage
-20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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