GLPBio

Integrin

Intergrin is a cell adhesion receptor for extracellular matrix protein binding. It is also involved in cell to cell interaction and triggers a variety of signaling pathways for cell proliferation, survival and mobility etc.

Products Related to Integrin(122)

  • GC70223 structure
    GC70223Fradafiban hydrochloride
    Purity: >99.00%

    Fradafiban (BIBU-52) hydrochloride is a nonpeptide platelet glycoprotein IIb/IIIa antagonist, which binds to the human platelet GP IIb/IIIa complex with a Kd value of 148 nM.

  • GC70986 structure
    GC70986Egaptivon pegol sodium
    Purity: >92.00%

    Egaptivon pegol sodium is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors.

  • GC72366 structure
    GC72366Volociximab
    CAS: 558480-40-3
    Purity: >95.50%

    Volociximab (M200) is a chimeric human/murine IgG4 antibody IIA1 targeting integrin α5β1 (EC50=0.2 nM).

  • GC72461 structure
    GC72461Rovelizumab
    CAS: 339086-79-2
    Purity: >97.00%

    Rovelizumab is a humanized monoclonal leukointegrin antibody.

  • GC73519 structure
    GC73519BT200 sodium
    Purity: >98.00%

    BT200 sodium, a pegylated form of the aptamer BT100, inhibits binding of von Willebrand factor (VWF) to platelet glycoprotein GPIb, preventing arterial thrombosis.

  • GC74342 structure
    GC74342Obtustatin triacetate
    Purity: >99.00%

    Obtustatin triacetate is a 41-residue non-RGD disintegrin.

  • GC74346 structure
    GC74346A20FMDV2
    CAS: 932699-03-1
    Purity: >98.00%

    A20FMDV2 is a selective αvβ6 integrin inhibitor (IC50: 3 nM), with an activity 1,000-fold more selective for αvβ6 than for other RGD-directed integrins (αvβ3, αvβ5, and α5β1).

  • GC74395 structure
    GC74395Synstatin (92-119)
    CAS: 1259384-47-8
    Purity: >97.00%

    Synstatin (92-119) is an anti-tumor agent that inhibits angiogenesis and cancer cell invasion.

  • GC74401 structure
    GC74401cRGDfK-thioacetyl ester TFA
    Purity: >99.00%

    cRGDfK-thioacetyl ester TFA is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging.

  • GC74470 structure
    GC74470Veltuzumab
    CAS: 728917-18-8
    Purity: >99.00%

    Veltuzumab (IMMU-106) is a humanized anti-CD20 monoclonal antibody.

  • GC74710 structure
    GC747102-Methylbutyrylcarnitine chloride
    Purity: >98.00%

    2-Metlbutyrylcarnitine (chloride) is a gut microbial metabolite which binds to integrin α2β1 in platelets, potentiating cytosolic phospholipase A2 (cPLA2) activation and platelet perresponsiveness.

  • GC79131 structure
    GC79131Furtisetabart
    CAS: 3055975-56-6
    Purity: >99.00%

    Furtisetabart is a humanized monoclonal antibody targeting CD147 with anti-tumor activity.

  • GC79132 structure
    GC79132Fibronectin sctive fragment control acetate
    Purity: >99.00%

    Fibronectin active fragment control acetate is an active peptide fragment of fibronectin.

  • GC79133 structure
    GC79133α4β7 Integrin-IN-2
    CAS: 2640360-68-3
    Purity: >98.00%

    α4β7 Integrin-IN-2 is an inhibitor of human α4β7 integrin with an IC 50 <5 nM.

  • GC79134 structure
    GC79134GREDVGC
    CAS: 1810716-06-3
    Purity: >99.00%

    GREDVGC is a peptide.

  • GC79135 structure
    GC79135c-RGD-SH TFA
    Purity: >98.50%

    c-RGD-SH TFA is an Integrin αvβ3 ligand.

  • GC79136 structure
    GC79136Deethyl-emvistegrast TFA
    Purity: >98.50%

    Deethyl-emvistegrast TFA is a quinoline derivative and also a α4β7 integrin inhibitor.

  • GC79137 structure
    GC79137C16Y acetate
    Purity: >98.50%

    C16Y acetate is a short peptide and an inhibitor of integrins αvβ3 and α5β1.

  • GC79140 structure
    GC79140Cyclo(-RGDfK), 5/6 FAM labeled TFA
    Purity: >98.00%

    Cyclo(-RGDfK), 5/6 FAM labeled TFA is a Cyclo(-RGDfK) TFA labeled with 5/6 FAM.

  • GC79141 structure
    GC79141T7 Peptide TFA
    Purity: >98.00%

    T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor.

  • GC79995 structure
    GC79995(S,R)-Emvistegrast
    CAS: 2417307-56-1
    Purity: >98%

    (S,R)-Emvistegrast ((S,R)-GS-1427) is an isomer of Emvistegrast.

  • GC81350 structure
    GC81350THR-123 TFA
    Purity: >99.50%

    THR-123 TFA is an orally active ALK3 peptide agonist.

  • GC81556 structure
    GC81556FZ1 peptide
    Purity: >99.50%

    FZ1 peptide is a cyclic heptapeptide and also an integrin αvβ3 agonist.

  • GC81830 structure
    GC81830D-RGDW acetate
    Purity: >98.00%

    D-RGDW acetate is an Arg-Gly-Asp (RGD) containing peptide.