GLPBio

PAR1

PAR1 (protease-activated receptor 1) is a subfamily of related G protein-coupled receptors that are activated by cleavage of part of their extracellular domain.

Products Related to PAR1(43)

  • GC38329 structure
    GC38329GB-110 hydrochloride
    Purity: >99.50%

    GB-110 hydrochloride is a potent, orally active, and nonpeptidic protease activated receptor 2 (PAR2) agonist.

  • GC38731 structure
    GC387312-Furoyl-LIGRLO-amide TFA
    CAS: 2468029-34-5
    Purity: >98%

    2-Furoyl-LIGRLO-amide TFA is a potent and selective proteinase-activated receptor 2 (PAR2) agonist with a pD2 value of 7.0.

  • GC60807 structure
    GC60807ENMD-1068 hydrochloride
    CAS: 789488-77-3
    Purity: >98.00%

    Selective protease-activated receptor 2 (PAR2) anatagonist

  • GC61316 structure
    GC61316tcY-NH2 TFA
    CAS: 1262750-73-1
    Purity: >99.50%

    tcY-NH2 ((trans-Cinnamoyl)-YPGKF-NH2) TFA is a potent selective PAR4 antagonist peptide.

  • GC61456 structure
    GC61456Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA
    CAS: 1872435-09-0
    Purity: >99.50%

    Protease-Activated Receptor-3 (PAR-3) (1-6), human TFA is a proteinase-activated receptor (PAR-3) agonist peptide.

  • GC61501 structure
    GC61501FSLLRY-NH2 TFA
    Purity: >98.00%

    FSLLRY-NH2 TFA is a protease-activated receptor 2 (PAR2) inhibitor.

  • GC61777 structure
    GC61777RWJ-56110 dihydrochloride
    CAS: 2387505-58-8
    Purity: >98%

    RWJ-56110 dihydrochloride is a potent, selective, peptide-mimetic inhibitor of PAR-1 activation and internalization (binding IC50=0.44 uM) and shows no effect on PAR-2, PAR-3, or PAR-4.

  • GC62101 structure
    GC62101PAR-2-IN-1
    CAS: 1690176-75-0
    Purity: >99.50%

    PAR-2-IN-1 is a protease-activated receptor-2 (PAR2) signaling pathway inhibitor with anti-inflammatory and anticancer effects.

  • GC62469 structure
    GC62469Protease-Activated Receptor-1, PAR-1 Agonist TFA
    Purity: >99.00%

    Protease-Activated Receptor-1, PAR-1 Agonist TFA is a selective proteinase-activated receptor1 (PAR-1) agonist peptide. Protease-Activated Receptor-1, PAR-1 Agonist TFA corresponds to PAR1 tethered ligand and which can selectively mimic theactions of thrombin via this receptor.

  • GC63540 structure
    GC63540SCH79797
    CAS: 245520-69-8
    Purity: >98.00%

    SCH79797 is a highly potent, selective nonpeptide protease activated receptor 1 (PAR1) antagonist.

  • GC63658 structure
    GC63658Atopaxar
    CAS: 751475-53-3
    Purity: >98%

    Atopaxar (E5555) is a potent, orally active, selective and reversible thrombin receptor protease-activated receptor-1 (PAR-1) antagonist.

  • GC64347 structure
    GC64347Vorapaxar sulfate
    CAS: 705260-08-8
    Purity: >99.00%

    Vorapaxar sulfate (SCH 530348 sulfate), an antiplatelet agent, is a selective, orally active, and competitive thrombin receptor protease-activated receptor (PAR-1) antagonist (Ki=8.1 nM).

  • GC64979 structure
    GC64979I-191
    CAS: 1690172-25-8
    Purity: >99.00%

    I-191 is a potent, selective protease-activated receptor 2 (PAR2) antagonist.

  • GC65312 structure
    GC65312AZ8838
    CAS: 2100285-41-2
    Purity: >98%

    AZ8838 is a potent, competitive, allosteric, orally active non-peptide small molecule antagonist of PAR2 with a pKi of 6.4 for hPAR2.

  • GC65439 structure
    GC65439GB-88
    CAS: 1416435-96-5
    Purity: >98.00%

    GB-88 is an oral, selective non-peptide antagonist of PAR2, inhibits PAR2 activated Ca2+ release with an IC50 of 2 ?M.

  • GC65529 structure
    GC65529TRAP-6 amide
    CAS: 141923-40-2
    Purity: >98.00%

    TRAP-6 amide is a PAR-1 thrombin receptor agonist peptide.

  • GC69663 structure
    GC69663Parstatin(mouse) TFA
    Purity: >98%

    Parstatin (mouse) TFA is a peptide agonist of the PAR-1 thrombin receptor with cell-penetrating properties and an effective inhibitor of angiogenesis.

  • GC69768 structure
    GC69768Protease-Activated Receptor-1, PAR-1 Agonist
    CAS: 141136-85-8
    Purity: >98%

    Protease-Activated Receptor-1, PAR-1 Agonist is a selective peptide that activates Protease-Activated Receptor-1 (PAR-1), which corresponds to the PAR1 ligand and selectively mimics the action of thrombin through this receptor.

  • GP10085 structure
    GP10085Thrombin Receptor Activator for Peptide 5 (TRAP-5)
    CAS: 141685-53-2
    Purity: >98%