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Home >> Signaling Pathways >> Neuroscience >> Dopamine Receptor

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products for  Dopamine Receptor

  1. Cat.No. Product Name Information
  2. GC37055 Quetiapine D4 fumarate Quetiapine D4 fumarate is the deuterium labeled Quetiapine fumarate. Quetiapine D4 fumarate Chemical Structure
  3. GC39724 Quetiapine D4 hemifumarate Quetiapine D4 hemifumarate is the deuterium labeled Quetiapine hemifumarate. Quetiapine D4 hemifumarate Chemical Structure
  4. GC16891 Quetiapine Fumarate Quetiapine Fumarate is a 5-HT receptors agonist with a pEC50 of 4.77 for human 5-HT1A receptor. Quetiapine Fumarate Chemical Structure
  5. GC30840 Quinagolide hydrochloride (CV205-502 hydrochloride) Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor. Quinagolide hydrochloride (CV205-502 hydrochloride) Chemical Structure
  6. GC17192 Quinelorane hydrochloride Quinelorane hydrochloride (LY163502) is a potent dopamine D3/D2 receptor agonist. Quinelorane hydrochloride Chemical Structure
  7. GC37067 rac-Rotigotine Hydrochloride rac-Rotigotine Hydrochloride is a racemate of Rotigotine. rac-Rotigotine Hydrochloride Chemical Structure
  8. GC16769 Raclopride dopamine D2/D3 receptor antagonist Raclopride Chemical Structure
  9. GC14822 Remoxipride hydrochloride Dopamine D2 receptor antagonist Remoxipride hydrochloride Chemical Structure
  10. GC12986 Risperidone

    SR-2A inhibitor

     Risperidone Chemical Structure
  11. GC37539 Risperidone hydrochloride Risperidone hydrochloride (R 64 766 hydrochloride) 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively. Risperidone hydrochloride Chemical Structure
  12. GC37540 Risperidone mesylate Risperidone mesylate(R 64 766 mesylate) is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Kis of 4.8, 5.9 nM for 5-HT2A and dopamine D2 receptor, respectively. Risperidone mesylate Chemical Structure
  13. GC12428 Ro 10-5824 dihydrochloride dopamine D4 receptor partial agonist Ro 10-5824 dihydrochloride Chemical Structure
  14. GC11462 Ropinirole HCl Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor. Ropinirole HCl Chemical Structure
  15. GC10614 Rotigotine A non-selective dopamine receptor agonist Rotigotine Chemical Structure
  16. GC37562 Rotigotine D7 Hydrochloride Rotigotine (N-0923) D7 Hydrochloride is the deuterium labeled Rotigotine(N-0923), which is a dopamine D2 and D3 receptor agonist. Rotigotine D7 Hydrochloride Chemical Structure
  17. GC16017 Rotigotine hydrochloride A non-selective dopamine receptor agonist Rotigotine hydrochloride Chemical Structure
  18. GC14657 Rotundine Dopamine D1 receptor antagonist,potent and selective Rotundine Chemical Structure
  19. GC10745 Roxindole hydrochloride Dopamine D2 autoreceptor agonist Roxindole hydrochloride Chemical Structure
  20. GC14865 RuBi-Dopa dopamine receptor activator RuBi-Dopa Chemical Structure
  21. GC13183 SB 277011A dihydrochloride SB 277011A dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively. SB 277011A dihydrochloride Chemical Structure
  22. GC37600 SB-277011 SB-277011 is a potent and delective dopamine D3 receptor antagonist (pKi values are 8.0, 6.0, 5.0 and <5.2 for D3, D2, 5-HT1D and 5-HT1B respectively); brain penetrant. SB-277011 Chemical Structure
  23. GC60334 SB-277011 hydrochloride SB-277011 hydrochloride (SB-277011A hydrochloride) is a potent, selective, orally bioavailable and brain penetrate?dopamine D3?receptor (D3R)?antagonist with Ki values of 10.7?nM and?11.2 nM?at?rodent and human?D3R, respectively. SB-277011 hydrochloride Chemical Structure
  24. GC37598 SB269652 SB269652 is the first drug-like allosteric modulator of the dopamine D2 receptor (D2R); a new chemical probe that can differentiate D2R monomers from dimers or oligomers depending on the observed pharmacology. SB269652 Chemical Structure
  25. GC10892 SCH 23390 hydrochloride SCH 23390 hydrochloride is a highly potent and selective dopamine D1-like receptor antagonist with a K(i) of 0.2 and 0.3 nM for the D1 and D5 dopamine receptor subtypes, respectively. SCH 23390 hydrochloride Chemical Structure
  26. GC16992 SCH 39166 hydrobromide Ecopipam (SCH 39166) hydrobromide is a potent, selective and orally active antagonist of dopamine D1/D5 receptor, with Kis of 1.2 nM and 2.0 nM, respectively. SCH 39166 hydrobromide Chemical Structure
  27. GC30787 Sertindole (Lu 23-174) Sertindole (Lu 23-174) (Lu 23-174) is an orally active 5-HT2A, 5-HT2C, dopamine D2, and αl-adrenergic receptors antagonist. Sertindole (Lu 23-174) Chemical Structure
  28. GC17769 Sitaxentan sodium Sitaxentan sodium (IPI 1040 sodium; TBC11251 sodium) is an orally active, highly selective antagonist of endothelin A receptors. Sitaxentan sodium Chemical Structure
  29. GC50644 SK 609 Dopamine D3 receptor biased agonist SK 609 Chemical Structure
  30. GC14048 SKF 38393 hydrobromide D1-like dopamine receptor partial agonist SKF 38393 hydrobromide Chemical Structure
  31. GC13169 SKF 77434 hydrobromide dopamine D1-like receptor partial agonist SKF 77434 hydrobromide Chemical Structure
  32. GC12158 SKF 81297 hydrobromide Dopamine D1-like receptor agonist SKF 81297 hydrobromide Chemical Structure
  33. GC33727 SKF 82958 ((±)-SKF 82958) SKF 82958 ((±)-SKF 82958) ((±)-SKF 82958) is a dopamine D1 receptor full agonist (K0.5=4 nM), displays selective for D1 over D2 receptors (K0.5=73 nM). SKF 82958 ((±)-SKF 82958) Chemical Structure
  34. GC15016 SKF 83566 hydrobromide

    D1-like dopamine receptor antagonist

     SKF 83566 hydrobromide Chemical Structure
  35. GC69909 SKF 83822

    SKF 83822 is an atypical dopamine D1 receptor agonist. It activates adenylate cyclase (AC) but not phospholipase C (PLC). SKF 83822 has also been shown to stimulate AC through the production of cAMP. It can be used in research on schizophrenia.

     SKF 83822 Chemical Structure
  36. GC11503 SKF 83822 hydrobromide dopamine D1-like receptor agonist SKF 83822 hydrobromide Chemical Structure
  37. GC69910 SKF 83959

    SKF83959 is an effective selective partial agonist of dopamine D1-like receptors. The Ki values for rat D1, D5, D2 and D3 are 1.18, 7.56, 920 and 399 nM respectively. SKF83959 is also an effective sigma (σ)-1 receptor allosteric modulator. It belongs to the benzazepine family and has been shown to improve cognitive dysfunction. SKF83959 can be used in research on Alzheimer's disease and depression.

     SKF 83959 Chemical Structure
  38. GC11146 SKF 83959 hydrobromide Dopamine D1-like receptor partial agonist SKF 83959 hydrobromide Chemical Structure
  39. GC33664 SKF-82958 hydrobromide ((±)-SKF 82958 hydrobromide) SKF-82958 ((±)-SKF 82958) hydrobromide is a dopamine D1 receptor full agonist (K0.5=4 nM), displays selective for D1 over D2 receptors (K0.5=73 nM). SKF-82958 hydrobromide ((±)-SKF 82958 hydrobromide) Chemical Structure
  40. GC61281 SKF-83566 SKF-83566 is a potent,?blood-brain permeable and orally active D1-like dopamine receptor (D1DR)?antagonist and a weaker competitive antagonist at the vascular 5-HT2?receptor (Ki=11 nM). SKF-83566 Chemical Structure
  41. GC17729 SKF38393 HCl SKF38393 HCl is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM. SKF38393 HCl Chemical Structure
  42. GC39184 Solriamfetol Solriamfetol Chemical Structure
  43. GC12015 Sonepiprazole rat and human dopamine D4 receptor antagonist Sonepiprazole Chemical Structure
  44. GC64885 Spiperone Spiperone is a potent dopamine D2, serotonin 5-HT1A, and serotonin 5-HT2A antagonist. Spiperone Chemical Structure
  45. GC37684 ST-836 ST-836 is a dopamine receptor ligand; Antiparkinsonian agent. ST-836 Chemical Structure
  46. GC37685 ST-836 hydrochloride ST-836 hydrochloride (compound 34) is a potent dopamine receptor ligand with Ki values of 4.5 nM, 132 nM for D3 and D2, respectively. ST-836 hydrochloride Chemical Structure
  47. GC31188 Sultopride (LIN-1418) Sultopride (LIN-1418) (LIN-1418) is a selective antagonist of dopamine D2 receptor. Sultopride (LIN-1418) Chemical Structure
  48. GC30944 Sultopride hydrochloride (LIN-1418 hydrochloride) Sultopride hydrochloride (LIN-1418 hydrochloride) (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor. Sultopride hydrochloride (LIN-1418 hydrochloride) Chemical Structure
  49. GC37702 Sumanirole maleate A dopamine D2 receptor agonist Sumanirole maleate Chemical Structure
  50. GC37729 Talipexole Talipexole (B-HT920) is a dopamine agonist that has been proposed as an antiparkinsonian agent. Talipexole Chemical Structure
  51. GN10513 Tetrahydroberberine,THB Tetrahydroberberine,THB Chemical Structure
  52. GN10740 Tetrahydropalmatine Tetrahydropalmatine Chemical Structure
  53. GC64934 Thiethylperazine Thiethylperazine, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine Chemical Structure
  54. GC64935 Thiethylperazine dimaleate Thiethylperazine dimaleate, a phenothiazine derivate, is an orally active and potent dopamine D2-receptor and histamine H1-receptor antagonist. Thiethylperazine dimaleate Chemical Structure
  55. GC11977 Thioridazine HCl Thioridazine HCl, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine HCl Chemical Structure
  56. GC17047 Threo-methylphenidate hydrochloride Threo-methylphenidate hydrochloride is an inhibitor of dopamine and norepinephrine transporters.. Threo-methylphenidate hydrochloride Chemical Structure
  57. GC30975 Tiapride hydrochloride Tiapride hydrochloride is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively. Tiapride hydrochloride Chemical Structure
  58. GC63240 Trifluoperazine

    Trifluoperazine (TFP) is an antagonist against dopamine receptors, act as antipsychotic agent and is widely used to treat schizophrenia or related psychoses .

     Trifluoperazine Chemical Structure
  59. GC13031 Trifluoperazine 2HCl Dopamine D2 receptor inhibitor Trifluoperazine 2HCl Chemical Structure
  60. GC30790 Triflupromazine hydrochloride A phenothiazine with diverse biological activities Triflupromazine hydrochloride Chemical Structure
  61. GC33527 Trimethobenzamide hydrochloride (Ro 2-9578) Trimethobenzamide hydrochloride (Ro 2-9578) is a blocker of the D2 receptor. Trimethobenzamide hydrochloride (Ro 2-9578) Chemical Structure
  62. GC16686 U 99194 maleate D3 antagonist U 99194 maleate Chemical Structure
  63. GC31287 U91356 U91356 is a dopamine receptor agonist. U91356 Chemical Structure
  64. GC70086 UCM-1306

    UCM-1306 is an orally effective positive allosteric modulator (PAM) of the human dopamine D1 receptor. UCM-1306 increases the maximal effect of endogenous dopamine (DA) in both human and mouse D1 receptors. It not only improves motor symptoms but also addresses key comorbid cognitive impairments associated with long-term Parkinson's disease (PD).

     UCM-1306 Chemical Structure
  65. GC65265 UNC9994 hydrochloride UNC9994 hydrochloride is a functionally selective, β-arrestin–biased dopamine D2 receptor (D2R) agonist that selectively activates β-arrestin recruitment and signaling. UNC9994 hydrochloride Chemical Structure
  66. GC70092 UNC9995

    UNC9995 is an agonist of the dopamine receptor Drd2. UNC9995 inhibits NLRP3 inflammasome activation by enhancing β-arrestin2-NLRP3 interaction, thereby preventing neuronal degeneration. In addition, UNC9995 activates Drd2/β-arrestin2 signaling to block inflammation-related gene transcription induced by JAK/STAT3. UNC9995 also improves depressive behavior in mouse models and ameliorates astrocyte dysfunction.

     UNC9995 Chemical Structure
  67. GC13322 Vanoxerine potent and selective DRI (Dopamine reuptake inhibitor) Vanoxerine Chemical Structure
  68. GC17741 Vanoxerine dihydrochloride potent and selective DRI (Dopamine reuptake inhibitor) Vanoxerine dihydrochloride Chemical Structure
  69. GC30824 Veralipride ((±)-Veralipride) Veralipride ((±)-Veralipride) is a D2 receptor antagonist. Veralipride ((±)-Veralipride) Chemical Structure
  70. GC10108 WAY-100635 A serotonin 5-HT1A antagonist WAY-100635 Chemical Structure
  71. GC15754 WAY-100635 Maleate 5-HT1A receptor agonist WAY-100635 Maleate Chemical Structure
  72. GC16270 WAY-100635 maleate salt A serotonin 5-HT1A antagonist WAY-100635 maleate salt Chemical Structure
  73. GC50027 Xaliproden hydrochloride High affinity 5-HT1A agonist; orally active Xaliproden hydrochloride Chemical Structure
  74. GC11020 Ziprasidone Ziprasidone Chemical Structure
  75. GC61389 Ziprasidone amino acid Ziprasidone amino acid (Ziprasidone Impurity C) is an impurity of Ziprasidone. Ziprasidone amino acid Chemical Structure
  76. GC37969 Ziprasidone D8 Ziprasidone D8 is deuterium labeled Ziprasidone, which is a combined 5-HT (serotonin) and dopamine receptor antagonist which exhibits potent effects of antipsychotic activity. Ziprasidone D8 Chemical Structure
  77. GC11521 Ziprasidone HCl Ziprasidone (CP-88059) hydrochloride is an orally active combined 5-HT and dopamine receptor antagonist. Ziprasidone HCl Chemical Structure
  78. GC13627 Ziprasidone hydrochloride monohydrate An atypical antipsychotic Ziprasidone hydrochloride monohydrate Chemical Structure
  79. GC45188 Zuclopenthixol Zuclopenthixol is a dopamine receptor antagonist (Kis = 9.8 and 1.5 nM for D1 and D2 receptors, respectively). Zuclopenthixol Chemical Structure
  80. GC70176 Zuclopenthixol dihydrochloride

    Zuclopenthixol dihydrochloride is a thioxanthene derivative and an antagonist of dopamine D1/D2 receptors. It can be used for research on schizophrenia.

     Zuclopenthixol dihydrochloride Chemical Structure
  81. GC63330 Zuclopenthixol-d4 succinate salt Zuclopenthixol-d4 succinate salt Chemical Structure

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