Dopamine Receptor
Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.
Products Related to Dopamine Receptor(300)
- GC11977Thioridazine hydrochlorideCAS: 130-61-0Purity: >99.50%
Thioridazine HCl, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities.
- GC12179GBR 13069 dihydrochlorideCAS: 67469-45-8Purity: >98%
GBR 13069 dihydrochloride is a selective dopamine uptake inhibitor (IC 50 =40~51nM).
- GC12428Ro 10-5824 dihydrochlorideCAS: 189744-94-3Purity: >99.50%
dopamine D4 receptor partial agonist
- GC12870(+)-UH 232 maleateCAS: 95999-12-5Purity: >98%
(+)-UH 232 maleate is a selective dopamine D₂ autoreceptor-preferring antagonist (Ki=72.7nM) and a partial agonist at the D₃ receptor (Ki≈9.4nM).
- GC12986RisperidoneCAS: 106266-06-2Purity: >98.00%
Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Ki values of 4.8, 5.9nM for 5-HT2A and dopamine D2 receptor, respectively.
- GC13036L-741,742 hydrochlorideCAS: 874882-93-6Purity: >98%
highly potent and selective D4 dopamine receptor antagonist
- GC13156(+)-AJ 76 hydrochlorideCAS: 85379-09-5Purity: >98%
(+)-AJ 76 hydrochloride is a dopamine receptors (DRs) antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3, hD4, hD2S, hD2L and rD2 receptors respectively).
- GC13183SB 277011A dihydrochlorideCAS: 1226917-67-4Purity: >98%
SB 277011A dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively.
- GC13625Pramipexole dihydrochlorideCAS: 104632-25-9Purity: >99.50%
A dopamine D 2S , D 2L , D 3 , and D 4 receptor agonist
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC11945 | BTCP maleate | 207455-25-2 | >98% | |
dopamine reuptake inhibitor | ||||
| GC11977 | Thioridazine hydrochloride | 130-61-0 | >99.50% | |
Thioridazine HCl, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. | ||||
| GC12015 | Sonepiprazole | 170858-33-0 | >98% | |
rat and human dopamine D4 receptor antagonist | ||||
| GC12158 | SKF 81297 hydrobromide | 67287-39-2 | >98% | |
Dopamine D1-like receptor agonist | ||||
| GC12179 | GBR 13069 dihydrochloride | 67469-45-8 | >98% | |
GBR 13069 dihydrochloride is a selective dopamine uptake inhibitor (IC 50 =40~51nM). | ||||
| GC12293 | Perphenazine | 58-39-9 | >99.50% | |
dopamine antagonist | ||||
| GC12355 | Eticlopride hydrochloride | 97612-24-3 | >98% | |
dopamine D2/D3 receptor antagonist | ||||
| GC12428 | Ro 10-5824 dihydrochloride | 189744-94-3 | >99.50% | |
dopamine D4 receptor partial agonist | ||||
| GC12456 | GBR 12783 dihydrochloride | 67469-75-4 | >98.00% | |
dopamine uptake inhibitor | ||||
| GC12466 | FAUC-365 | 474432-66-1 | >98% | |
D3 dopamine receptor agonist | ||||
| GC12495 | Olanzapine | 132539-06-1 | >99.50% | |
Olanzapine is a monoamine antagonist. | ||||
| GC12543 | Nemonapride | 75272-39-8 | >98% | |
dopamine D2-like receptor antagonist | ||||
| GC12641 | 3-CPMT | 14008-79-8 | >99.00% | |
dopamine uptake inhibitor | ||||
| GC12800 | PAOPA | 114200-31-6 | >98% | |
dopamine D2 receptor modulator | ||||
| GC12870 | (+)-UH 232 maleate | 95999-12-5 | >98% | |
(+)-UH 232 maleate is a selective dopamine D₂ autoreceptor-preferring antagonist (Ki=72.7nM) and a partial agonist at the D₃ receptor (Ki≈9.4nM). | ||||
| GC12986 | Risperidone | 106266-06-2 | >98.00% | |
Risperidone is a serotonin 5-HT2 receptor blocker, P-Glycoprotein inhibitor and potent dopamine D2 receptor antagonist, with Ki values of 4.8, 5.9nM for 5-HT2A and dopamine D2 receptor, respectively. | ||||
| GC13031 | Trifluoperazine 2HCl | 440-17-5 | >98.00% | |
Dopamine D2 receptor inhibitor | ||||
| GC13036 | L-741,742 hydrochloride | 874882-93-6 | >98% | |
highly potent and selective D4 dopamine receptor antagonist | ||||
| GC13109 | Fananserin | 127625-29-0 | >99.50% | |
5-HT2A receptor antagonist | ||||
| GC13156 | (+)-AJ 76 hydrochloride | 85379-09-5 | >98% | |
(+)-AJ 76 hydrochloride is a dopamine receptors (DRs) antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3, hD4, hD2S, hD2L and rD2 receptors respectively). | ||||
| GC13169 | SKF 77434 hydrobromide | 300561-58-4 | >98% | |
dopamine D1-like receptor partial agonist | ||||
| GC13183 | SB 277011A dihydrochloride | 1226917-67-4 | >98% | |
SB 277011A dihydrochloride (SB-277011A dihydrochloride) is a potent, selective, orally bioavailable and brain penetrate dopamine D3 receptor antagonist, with pKis of 8.0, 6.0, <5.2 and 5.9 for D3, D2, 5-HT1B, and 5-HT1D receptors, respectively. | ||||
| GC13573 | Nomifensine | 32795-47-4 | >99.50% | |
noradrenalin and dopamine uptake inhibitor | ||||
| GC13625 | Pramipexole dihydrochloride | 104632-25-9 | >99.50% | |
A dopamine D 2S , D 2L , D 3 , and D 4 receptor agonist | ||||