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Home >> Signaling Pathways >> Neuroscience >> Dopamine Receptor

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products for  Dopamine Receptor

  1. Cat.No. Product Name Information
  2. GC33544 (±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6) (±)-Levomepromazine D6 ((±)-Methotrimeprazine D6) is the deuterium labeled Methotrimeprazine, which is a D3 dopamine and Histamine H1 receptor antagonist. (±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6) Chemical Structure
  3. GC13156 (+)-AJ 76 hydrochloride Dopamine receptor antagonist (+)-AJ 76 hydrochloride Chemical Structure
  4. GC30848 (+)-PD 128907 hydrochloride

    A potent D3 receptor agonist

     (+)-PD 128907 hydrochloride Chemical Structure
  5. GC12870 (+)-UH 232 maleate D2 antagonist (+)-UH 232 maleate Chemical Structure
  6. GC34949 (-)-Isocorypalmine An isoquinoline alkaloid and metabolite of L-THP with diverse biological activities (-)-Isocorypalmine Chemical Structure
  7. GC17877 (-)-Quinpirole hydrochloride dopamine D2 receptor agonist (-)-Quinpirole hydrochloride Chemical Structure
  8. GC68383 (R)-Preclamol (R)-Preclamol Chemical Structure
  9. GC62745 (Rac)-PF-06256142 (Rac)-PF-06256142 is the less effective enantiomer of PF-06256142. (Rac)-PF-06256142 Chemical Structure
  10. GC10349 (RS)-(±)-Sulpiride (RS)-(±)-Sulpiride is a D2 receptor a antagonist, an atypical antipsychotic drug of the benzamide class, used mainly in the treatment of psychosis associated with schizophrenia and major depressive disorder, and sometimes used in low dosage to treat anxiety and mild depression. (RS)-(±)-Sulpiride Chemical Structure
  11. GC63655 (S)-Amisulpride (S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride Chemical Structure
  12. GC13786 (±)-Salsolinol (hydrochloride) depolarize dopamineric neurons (±)-Salsolinol (hydrochloride) Chemical Structure
  13. GC14252 (–)-Stepholidine A dopamine receptor antagonist and 5-HT1A partial agonist (–)-Stepholidine Chemical Structure
  14. GC60017 2'-O-Methylisoliquiritigenin 2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway. 2'-O-Methylisoliquiritigenin Chemical Structure
  15. GC14873 2-CMDO Dopamine D2-like receptor antagonist 2-CMDO Chemical Structure
  16. GC15856 3'-Fluorobenzylspiperone maleate

    ligand for the D2 receptor

     3'-Fluorobenzylspiperone maleate Chemical Structure
  17. GC15606 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride dopamine uptake and transport inhibitor 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride Chemical Structure
  18. GC12641 3-CPMT dopamine uptake inhibitor 3-CPMT Chemical Structure
  19. GC60505 3-O-Methyldopa 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa Chemical Structure
  20. GC60506 3-O-Methyldopa D3 3-O-Methyldopa D3 (3-Methoxy-L-tyrosine-d3) is deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa D3 Chemical Structure
  21. GC14311 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride dopamine release inhibitor 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride Chemical Structure
  22. GC16267 6-Hydroxydopamine hydrobromide Oxidopamine (6-OHDA) hydrobromide is an antagonist of the neurotransmitter dopamine. 6-Hydroxydopamine hydrobromide Chemical Structure
  23. GC16574 7-Hydroxy-DPAT hydrobromide D3 dopamine receptor agonist 7-Hydroxy-DPAT hydrobromide Chemical Structure
  24. GC14610 A 412997 dihydrochloride Selective D4 agonist A 412997 dihydrochloride Chemical Structure
  25. GC15498 A 68930 hydrochloride Agonist of D1-like dopamine receptor,potent and selective A 68930 hydrochloride Chemical Structure
  26. GC11183 A 77636 hydrochloride Agonist of D1-like dopamine receptor,potent and selective A 77636 hydrochloride Chemical Structure
  27. GC19499 A-381393

    A-381393 is a potent, selective, brain penetrate dopamine D4 receptor antagonist

     A-381393 Chemical Structure
  28. GC31214 A-437203 (Lu201640) A-437203 (Lu201640) is a selective D3 receptor antagonist with Ki of 71, 1.6, and 6220 nM for D2, D3, and D4 receptors, respectively. A-437203 (Lu201640) Chemical Structure
  29. GC31055 Abaperidone Abaperidone is a potent antagonist of 5-HT2A?receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM. Abaperidone Chemical Structure
  30. GC11795 ABT 724 trihydrochloride Dopamine D4 receptor agonist,potent and selective ABT 724 trihydrochloride Chemical Structure
  31. GC33552 ABT-670 ABT-670 is a selective, oral bioavailable agonist of dopamine D4 receptor, with EC50 of 89 nM, 160 nM, and 93 nM for human?D4, ferret?D4, and rat?D4, respectively. ABT-670 Chemical Structure
  32. GC35252 Adoprazine Adoprazine (SLV313) is a full 5-HT1A receptor agonist with a pEC50 of 9 at cloned h5-HT1A receptors. Adoprazine Chemical Structure
  33. GC15546 Alizapride HCl Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride HCl Chemical Structure
  34. GC10105 Amantadine HCl Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine HCl Chemical Structure
  35. GC17184 Ambrisentan ETA-receptor antagonist Ambrisentan Chemical Structure
  36. GC16049 AMI-193 AMI-193 (AMI-193) is a potent and selective antagonist of 5-HT2 and dopamine D2 receptor, with Kis of 2 nM and 3 nM, respectively. AMI-193 Chemical Structure
  37. GC12610 Amisulpride Dopamine D2/D3 receptor antagonist Amisulpride Chemical Structure
  38. GC35323 Amisulpride hydrochloride Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively. Amisulpride hydrochloride Chemical Structure
  39. GC63654 Aramisulpride Aramisulpride is a dopamine D2 receptor and serotonin receptor antagonist used for the research of metabolic disorders. Aramisulpride Chemical Structure
  40. GC10117 Aripiprazole 5-HT receptor partial agonist Aripiprazole Chemical Structure
  41. GC14518 Asenapine hydrochloride Asenapine hydrochloride Chemical Structure
  42. GC16229 Azaperone Dopamine antagonist Azaperone Chemical Structure
  43. GC14491 B-HT 920 A potent agonist of D2 receptors B-HT 920 Chemical Structure
  44. GC16782 Benocyclidine dopamine reuptake inhibitor Benocyclidine Chemical Structure
  45. GC35492 Benzamide Derivative 1 Benzamide Derivative 1 is a benzamide derivative from patent EP0213775A1, compound 18. Benzamide Derivative 1 Chemical Structure
  46. GC14160 Blonanserin Atypical antipsychotic Blonanserin Chemical Structure
  47. GC31278 BP 897 BP 897 is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist. BP 897 Chemical Structure
  48. GC11186 Brexpiprazole 5-HT2A, α1B-, and α2C-adrenergic receptors antagonist Brexpiprazole Chemical Structure
  49. GC60662 Brexpiprazole S-oxide

    Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4).

     Brexpiprazole S-oxide Chemical Structure
  50. GC64676 Brilaroxazine Brilaroxazine (RP5603) is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator. Brilaroxazine Chemical Structure
  51. GC13931 Bromocriptine mesylate

    D2-like dopamine receptor agonist

     Bromocriptine mesylate Chemical Structure
  52. GC31047 Bromopride A dopamine D2 receptor antagonist Bromopride Chemical Structure
  53. GC64924 Bromperidol hydrochloride Bromperidol (R-11333) hydrochloride possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride Chemical Structure
  54. GC11945 BTCP maleate dopamine reuptake inhibitor BTCP maleate Chemical Structure
  55. GC14714 Bupropion hydrochloride Dopamine/norepinephrine inhibitor Bupropion hydrochloride Chemical Structure
  56. GC10441 Cabergoline potent dopamine receptor agonist Cabergoline Chemical Structure
  57. GC15985 Cariprazine An atypical antipsychotic Cariprazine Chemical Structure
  58. GC35610 Cariprazine hydrochloride An atypical antipsychotic Cariprazine hydrochloride Chemical Structure
  59. GC46007 Cariprazine-d6 An internal standard for the quantification of cariprazine Cariprazine-d6 Chemical Structure
  60. GC38521 Carmoxirole hydrochloride Carmoxirole hydrochloride Chemical Structure
  61. GC14826 Carmoxirole hydrochloride dopamine D2 receptor agonist Carmoxirole hydrochloride Chemical Structure
  62. GC30995 CGP 25454A CGP 25454A is a novel and selective presynaptic dopamine autoreceptor antagonist. CGP 25454A Chemical Structure
  63. GC30280 Chlorpromazine D6 hydrochloride An internal standard for the quantification of chlorpromazine Chlorpromazine D6 hydrochloride Chemical Structure
  64. GC14216 Chlorpromazine HCl

    dopamine receptor antagonist

     Chlorpromazine HCl Chemical Structure
  65. GC15312 Chlorprothixene Dopamine receptor antagonist Chlorprothixene Chemical Structure
  66. GC17656 Chlorprothixene (hydrochloride) dopamine D2 receptor antagonist and GABAA receptor inhibitor Chlorprothixene (hydrochloride) Chemical Structure
  67. GC10260 cis-Flupenthixol (hydrochloride) cis-Flupenthixol (hydrochloride) is a potent and selective DA D1/D2 receptor antagonist, with Ki values of 0.38 nM and 7 nM for D2 receptor and 5-HT2A, respectively. cis-Flupenthixol (hydrochloride) Chemical Structure
  68. GC31418 Clebopride malate Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Clebopride malate Chemical Structure
  69. GC31037 Clocapramine (Clocarpramine) Clocapramine (Clocarpramine) Chemical Structure
  70. GC30375 Clomipramine D3 Clomipramine D3 (Chlorimipramine-d3) is the deuterium labeled Clomipramine. Clomipramine D3 Chemical Structure
  71. GC15107 Clomipramine HCl Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine HCl Chemical Structure
  72. GC47101 Clomipramine-d3 (hydrochloride) An Analytical Reference Standard Clomipramine-d3 (hydrochloride) Chemical Structure
  73. GC17760 Clozapine Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine Chemical Structure
  74. GC50193 Clozapine - d8 Clozapine - d8 (HF 1854-d8) is the deuterium labeled Clozapine. Clozapine - d8 Chemical Structure
  75. GC10822 Clozapine N-oxide (CNO)

    A metabolite of clozapine and muscarinic DREADD agonist

     Clozapine N-oxide (CNO) Chemical Structure
  76. GC15792 CY 208-243 dopamine D1 receptor agonist CY 208-243 Chemical Structure
  77. GC38228 D-Tetrahydropalmatine D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis. D-Tetrahydropalmatine Chemical Structure
  78. GC62926 Desmethyl cariprazine Desmethyl cariprazine is an active metabolite of Cariprazine. Desmethyl cariprazine Chemical Structure
  79. GC35847 Dexpramipexole Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. Dexpramipexole Chemical Structure
  80. GC35848 Dexpramipexole dihydrochloride An anti-apoptotic antioxidant Dexpramipexole dihydrochloride Chemical Structure
  81. GC35864 Dihydrexidine Dihydrexidine (DAR-0100) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist with an IC50 of 10 nM for D1 receptor. Dihydrexidine Chemical Structure
  82. GC17527 Dihydrexidine hydrochloride dopamine D1 agonist Dihydrexidine hydrochloride Chemical Structure
  83. GC10144 Domperidone Drug for gastroparesis Domperidone Chemical Structure
  84. GC62940 Dopamine

    Dopamine is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain.

     Dopamine Chemical Structure
  85. GC11028 Dopamine HCl Dopamine D1-5 receptors agonist Dopamine HCl Chemical Structure
  86. GC30772 Dopamine serotonin antagonist-1 Dopamine serotonin antagonist-1 Chemical Structure
  87. GC10808 Droperidol Dopamine-2 receptor antagonist Droperidol Chemical Structure
  88. GC12355 Eticlopride hydrochloride dopamine D2/D3 receptor antagonist Eticlopride hydrochloride Chemical Structure
  89. GC39757 Etilevodopa hydrochloride Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa hydrochloride Chemical Structure
  90. GC13109 Fananserin 5-HT2A receptor antagonist Fananserin Chemical Structure
  91. GC62972 FAUC 346 FAUC 346, a highly selective D3 partial agonist (EC50 = 1.5 nM), also demonstrates an inhibitory effect on cocaine-seeking behavior. FAUC 346 Chemical Structure
  92. GC12466 FAUC-365 D3 dopamine receptor agonist FAUC-365 Chemical Structure
  93. GC14759 Fenoldopam D1-like dopamine receptor partial agonist Fenoldopam Chemical Structure
  94. GC43660 Fenoldopam (mesylate) Fenoldopam is an agonist of dopamine D1A (D1R) and D1B (D5R) receptors (Kds = 17 and 11 nM, respectively). Fenoldopam (mesylate) Chemical Structure
  95. GC50018 Fenoldopam hydrochloride Selective D1-like partial agonist Fenoldopam hydrochloride Chemical Structure
  96. GC15326 Flupenthixol dihydrochloride Flupentixol is an orally active D1/D2 dopamine receptor antagonist and new PI3K inhibitor (PI3Kα IC50=127 nM). Flupenthixol dihydrochloride Chemical Structure
  97. GC39192 Fluphenazine decanoate Fluphenazine decanoate is a dopamine D2 receptor inhibitor, is a long-acting phenothiazine neuroleptic. Fluphenazine decanoate Chemical Structure
  98. GC14559 Fluphenazine dihydrochloride A phenothiazine-class D1DR and D2DR inhibitor Fluphenazine dihydrochloride Chemical Structure
  99. GC68307 Fluphenazine-d8 dihydrochloride Fluphenazine-d8 dihydrochloride Chemical Structure
  100. GC36069 Foscarbidopa Foscarbidopa (Carbidopa 4′-monophosphate) is a prodrug of Carbidopa, acts as a dopamine receptor agonist. Foscarbidopa Chemical Structure
  101. GC12456 GBR 12783 dihydrochloride dopamine uptake inhibitor GBR 12783 dihydrochloride Chemical Structure

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