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Home >> Signaling Pathways >> Neuroscience >> Dopamine Receptor

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products for  Dopamine Receptor

  1. Cat.No. Product Name Information
  2. GC33544 (±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6)

    (±)-Methotrimeprazine-d6; dl-Methotrimeprazine-d6

     (±)-Levomepromazine D6 ((±)-Methotrimeprazine D6) is the deuterium labeled Methotrimeprazine, which is a D3 dopamine and Histamine H1 receptor antagonist. (±)-Methotrimeprazine (D6) (dl-Methotrimeprazine D6) Chemical Structure
  3. GC13156 (+)-AJ 76 hydrochloride (+)-AJ 76 hydrochloride is a dopamine receptors (DRs) antagonist with preferential action at presynaptic receptors (pKi values are 6.95, 6.67, 6.37, 6.21 and 6.07 at hD3, hD4, hD2S, hD2L and rD2 receptors respectively). (+)-AJ 76 hydrochloride Chemical Structure
  4. GC17527 (+)-Dihydrexidine hydrochloride

    (+)-DAR-0100 hydrochloride

    (+)-Dihydrexidine hydrochloride ((+)-DAR-0100 hydrochloride) is a dopamine D1 receptor agonist with an EC50 of 72± 21 nM.

     (+)-Dihydrexidine hydrochloride Chemical Structure
  5. GC30848 (+)-PD 128907 hydrochloride

    A potent D3 receptor agonist

     (+)-PD 128907 hydrochloride Chemical Structure
  6. GC12870 (+)-UH 232 maleate D2 antagonist (+)-UH 232 maleate Chemical Structure
  7. GC69463 (-)-GSK598809 hydrochloride

    (1S,5R)-GSK598809 hydrochloride

    (-)-GSK598809 is an isomer of GSK598809. GSK598809 is a selective antagonist of the dopamine D3 receptor (DRD3).

     (-)-GSK598809 hydrochloride Chemical Structure
  8. GC34949 (-)-Isocorypalmine

    L-Isocorypalmine, Isocorypalmine

     An isoquinoline alkaloid and metabolite of L-THP with diverse biological activities (-)-Isocorypalmine Chemical Structure
  9. GC17877 (-)-Quinpirole hydrochloride

    (-)-LY 171555

     dopamine D2 receptor agonist (-)-Quinpirole hydrochloride Chemical Structure
  10. GC14252 (-)-Stepholidine A dopamine receptor antagonist and 5-HT1A partial agonist (-)-Stepholidine Chemical Structure
  11. GC68383 (R)-Preclamol

    (+)-3-PPP

     (R)-Preclamol Chemical Structure
  12. GC62745 (Rac)-PF-06256142 (Rac)-PF-06256142 is the less effective enantiomer of PF-06256142. (Rac)-PF-06256142 Chemical Structure
  13. GC10349 (RS)-(±)-Sulpiride

    rac-Sulpiride, RD 1403, (RS)-(±)-Sulpiride, (S)-Sulpiride

     (RS)-(±)-Sulpiride is a D2 receptor a antagonist, an atypical antipsychotic drug of the benzamide class, used mainly in the treatment of psychosis associated with schizophrenia and major depressive disorder, and sometimes used in low dosage to treat anxiety and mild depression. (RS)-(±)-Sulpiride Chemical Structure
  14. GC63655 (S)-Amisulpride (S)-Amisulpride (Esamisulpride) is a potent dopamine D2/D3 receptor antagonist. (S)-Amisulpride Chemical Structure
  15. GC13786 (±)-Salsolinol (hydrochloride) depolarize dopamineric neurons (±)-Salsolinol (hydrochloride) Chemical Structure
  16. GC60017 2'-O-Methylisoliquiritigenin 2'-O-Methylisoliquiritigenin, isolated from the Arachis species, up-regulates 5-HT, NE, DA and GABA pathways, but does not put a very significant effect on ne NE pathway. 2'-O-Methylisoliquiritigenin Chemical Structure
  17. GC14873 2-CMDO Dopamine D2-like receptor antagonist 2-CMDO Chemical Structure
  18. GC15856 3'-Fluorobenzylspiperone maleate

    ligand for the D2 receptor

     3'-Fluorobenzylspiperone maleate Chemical Structure
  19. GC15606 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride dopamine uptake and transport inhibitor 3α-Bis-(4-fluorophenyl) methoxytropane hydrochloride Chemical Structure
  20. GC12641 3-CPMT dopamine uptake inhibitor 3-CPMT Chemical Structure
  21. GC60505 3-O-Methyldopa 3-O-Methyldopa (3-Methoxy-L-tyrosine) is a metabolite of L-DOPA which is formed by catechol-O-methyltransferase (COMT). 3-O-Methyldopa Chemical Structure
  22. GC60506 3-O-Methyldopa D3 3-O-Methyldopa D3 (3-Methoxy-L-tyrosine-d3) is deuterium labeled 3-O-Methyldopa. 3-O-Methyldopa D3 Chemical Structure
  23. GC14311 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride dopamine release inhibitor 4-Phenyl-1,2,3,4-tetrahydroisoquinoline hydrochloride Chemical Structure
  24. GC16267 6-Hydroxydopamine hydrobromide

    6-hydroxy Dopamine, Oxidopamine, 2,4,5-Trihydroxyphenethylamine

     6-Hydroxydopamine hydrobromide (6-OHDA) is a structural analogue of catecholamines, dopamine and noradrenaline, and exerts its toxic effects on catecholaminergic neurons. 6-Hydroxydopamine hydrobromide Chemical Structure
  25. GC16574 7-Hydroxy-DPAT hydrobromide D3 dopamine receptor agonist 7-Hydroxy-DPAT hydrobromide Chemical Structure
  26. GC14610 A 412997 dihydrochloride Selective D4 agonist A 412997 dihydrochloride Chemical Structure
  27. GC15498 A 68930 hydrochloride Agonist of D1-like dopamine receptor,potent and selective A 68930 hydrochloride Chemical Structure
  28. GC11183 A 77636 hydrochloride Agonist of D1-like dopamine receptor,potent and selective A 77636 hydrochloride Chemical Structure
  29. GC19499 A-381393

    A-381393 is a potent, selective, brain penetrate dopamine D4 receptor antagonist

     A-381393 Chemical Structure
  30. GC31214 A-437203 (Lu201640)

    Lu201640; A37203

     A-437203 (Lu201640) is a selective D3 receptor antagonist with Ki of 71, 1.6, and 6220 nM for D2, D3, and D4 receptors, respectively. A-437203 (Lu201640) Chemical Structure
  31. GC31055 Abaperidone Abaperidone is a potent antagonist of 5-HT2A?receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM. Abaperidone Chemical Structure
  32. GC11795 ABT 724 trihydrochloride Dopamine D4 receptor agonist,potent and selective ABT 724 trihydrochloride Chemical Structure
  33. GC33552 ABT-670 ABT-670 is a selective, oral bioavailable agonist of dopamine D4 receptor, with EC50 of 89 nM, 160 nM, and 93 nM for human?D4, ferret?D4, and rat?D4, respectively. ABT-670 Chemical Structure
  34. GC35252 Adoprazine Adoprazine (SLV313) is a full 5-HT1A receptor agonist with a pEC50 of 9 at cloned h5-HT1A receptors. Adoprazine Chemical Structure
  35. GC15546 Alizapride HCl Alizapride is a potent antiemetic, acting as a dopamine receptor antagonist. Alizapride HCl Chemical Structure
  36. GC10105 Amantadine HCl

    Adamantylamine, Aminoadamantane, NSC 83653

     Amantadine (1-Adamantanamine) hydrochloride is an orally avtive and potent antiviral agent with activity against influenza A viruses. Amantadine HCl Chemical Structure
  37. GC17184 Ambrisentan ETA-receptor antagonist Ambrisentan Chemical Structure
  38. GC16049 AMI-193 AMI-193 (AMI-193) is a potent and selective antagonist of 5-HT2 and dopamine D2 receptor, with Kis of 2 nM and 3 nM, respectively. AMI-193 Chemical Structure
  39. GC12610 Amisulpride

    DAN 2163

     Dopamine D2/D3 receptor antagonist Amisulpride Chemical Structure
  40. GC35323 Amisulpride hydrochloride Amisulpride hydrochloride is a dopamine D2/D3 receptor antagonist with Kis of 2.8 and 3.2 nM for human dopamine D2 and D3, respectively. Amisulpride hydrochloride Chemical Structure
  41. GC63654 Aramisulpride

    R-(+)-Amisulpride

     Aramisulpride is a dopamine D2 receptor and serotonin receptor antagonist used for the research of metabolic disorders. Aramisulpride Chemical Structure
  42. GC10117 Aripiprazole

    OPC 31, OPC 14597

     5-HT receptor partial agonist Aripiprazole Chemical Structure
  43. GC14518 Asenapine hydrochloride Asenapine hydrochloride Chemical Structure
  44. GC16229 Azaperone

    Fluoperidol, NSC 170976

     Dopamine antagonist Azaperone Chemical Structure
  45. GC14491 B-HT 920 A potent agonist of D2 receptors B-HT 920 Chemical Structure
  46. GC16782 Benocyclidine

    BCP, Benzothiophenylcyclohexylpiperidine, BTCP, GK 13

     dopamine reuptake inhibitor Benocyclidine Chemical Structure
  47. GC35492 Benzamide Derivative 1 Benzamide Derivative 1 is a benzamide derivative from patent EP0213775A1, compound 18. Benzamide Derivative 1 Chemical Structure
  48. GC14160 Blonanserin

    AD5423, Lonasen

     Atypical antipsychotic Blonanserin Chemical Structure
  49. GC70745 Blonanserin-d5 Blonanserin-d5 is a deuterium labeled Blonanserin. Blonanserin-d5 Chemical Structure
  50. GC31278 BP 897 BP 897 is a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist. BP 897 Chemical Structure
  51. GC11186 Brexpiprazole

    OPC 34712

     5-HT2A, α1B-, and α2C-adrenergic receptors antagonist Brexpiprazole Chemical Structure
  52. GC60662 Brexpiprazole S-oxide

    Brexpiprazole S-oxide (DM-3411) is a main metabolite of Brexpiprazole and is metabolized by cytochrome P450 3A4 (CYP3A4).

     Brexpiprazole S-oxide Chemical Structure
  53. GC64676 Brilaroxazine

    RP5063

     Brilaroxazine (RP5603) is a potent and orally active multimodal dopamine (DA)/serotonin (5-HT) modulator. Brilaroxazine Chemical Structure
  54. GC13931 Bromocriptine mesylate

    CB-154

    D2-like dopamine receptor agonist

     Bromocriptine mesylate Chemical Structure
  55. GC31047 Bromopride

    Emepride, Emoril, Viadil

     A dopamine D2 receptor antagonist Bromopride Chemical Structure
  56. GC64924 Bromperidol hydrochloride

    R-11333 hydrochloride

     Bromperidol (R-11333) hydrochloride possesses antipsychotic activity, with a high affinity for central dopamine receptors D2. Bromperidol hydrochloride Chemical Structure
  57. GC11945 BTCP maleate dopamine reuptake inhibitor BTCP maleate Chemical Structure
  58. GC14714 Bupropion hydrochloride

    NSC 315851

     Dopamine/norepinephrine inhibitor Bupropion hydrochloride Chemical Structure
  59. GC10441 Cabergoline

    FCE 21336

     potent dopamine receptor agonist Cabergoline Chemical Structure
  60. GC15985 Cariprazine

    RGH-188

     An atypical antipsychotic Cariprazine Chemical Structure
  61. GC35610 Cariprazine hydrochloride

    RGH-188

     An atypical antipsychotic Cariprazine hydrochloride Chemical Structure
  62. GC46007 Cariprazine-d6 An internal standard for the quantification of cariprazine Cariprazine-d6 Chemical Structure
  63. GC38521 Carmoxirole hydrochloride Carmoxirole hydrochloride Chemical Structure
  64. GC14826 Carmoxirole hydrochloride

    EMD 45609 hydrochloride

     dopamine D2 receptor agonist Carmoxirole hydrochloride Chemical Structure
  65. GC30995 CGP 25454A CGP 25454A is a novel and selective presynaptic dopamine autoreceptor antagonist. CGP 25454A Chemical Structure
  66. GC30280 Chlorpromazine D6 hydrochloride

    CPZ-d6

     An internal standard for the quantification of chlorpromazine Chlorpromazine D6 hydrochloride Chemical Structure
  67. GC14216 Chlorpromazine HCl

    CPZ

     Chlorpromazine HCl is an orally effective, blood-brain-permeable phenothiazine antipsychotic that can effectively antagonize D2 dopamine receptors and 5-HT2A and has a strong sedative effect. Chlorpromazine HCl Chemical Structure
  68. GC15312 Chlorprothixene Dopamine receptor antagonist Chlorprothixene Chemical Structure
  69. GC17656 Chlorprothixene (hydrochloride)

    cis-Chlorprothixene,NSC 169899

     dopamine D2 receptor antagonist and GABAA receptor inhibitor Chlorprothixene (hydrochloride) Chemical Structure
  70. GC71717 Cinitapride Cinitapride is a nonselective 5-HT1 and 5-HT4 receptors agonist and a 5-HT2 and D2 antagonist. Cinitapride Chemical Structure
  71. GC10260 cis-Flupenthixol (hydrochloride)

    cis-Flupentixol

     cis-Flupenthixol (hydrochloride) is a potent and selective DA D1/D2 receptor antagonist, with Ki values of 0.38 nM and 7 nM for D2 receptor and 5-HT2A, respectively. cis-Flupenthixol (hydrochloride) Chemical Structure
  72. GC31418 Clebopride malate Clebopride malate is a dopamine antagonist drug with antiemetic and prokinetic properties used to treat functional gastrointestinal disorders. Clebopride malate Chemical Structure
  73. GC31037 Clocapramine (Clocarpramine)

    Clocarpramine; 3-Chlorocarpipramine

     Clocapramine (Clocarpramine) Chemical Structure
  74. GC30375 Clomipramine D3

    Chlorimipramine-d3; G-34586-d3; NSC-169865-d3

     Clomipramine D3 (Chlorimipramine-d3) is the deuterium labeled Clomipramine. Clomipramine D3 Chemical Structure
  75. GC15107 Clomipramine HCl Clomipramine (Chlorimipramine) hydrochloride is a potent 5-HT reuptake blocker with the IC50 value of 1.5 nM. Clomipramine HCl Chemical Structure
  76. GC47101 Clomipramine-d3 (hydrochloride) An Analytical Reference Standard Clomipramine-d3 (hydrochloride) Chemical Structure
  77. GC17760 Clozapine

    HF 1854

     Clozapine (HF 1854) is an antipsychotic used for the research of schizophrenia. Clozapine Chemical Structure
  78. GC50193 Clozapine - d8

    HF 1854-d8

     Clozapine - d8 (HF 1854-d8) is the deuterium labeled Clozapine. Clozapine - d8 Chemical Structure
  79. GC10822 Clozapine N-oxide (CNO)

    CNO

     Clozapine N-oxide(CNO) is a potent dopamine antagonist and also a potent and selective muscarinic M4 receptor (EC50=11 nM) agonist. Clozapine N-oxide (CNO) Chemical Structure
  80. GC15792 CY 208-243 dopamine D1 receptor agonist CY 208-243 Chemical Structure
  81. GC38228 D-Tetrahydropalmatine

    (+)-Corydalis B, (+)-Tetrahydropalmatine, (R)-Tetrahydropalmatine, D-THP

     D-Tetrahydropalmatine is an isoquinoline alkaloid, mainly in the genus Corydalis. D-Tetrahydropalmatine Chemical Structure
  82. GC62926 Desmethyl cariprazine Desmethyl cariprazine is an active metabolite of Cariprazine. Desmethyl cariprazine Chemical Structure
  83. GC35847 Dexpramipexole Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine agonist. Dexpramipexole Chemical Structure
  84. GC35848 Dexpramipexole dihydrochloride

    Dexpramipexole, KNS 760704, (+)-Pramipexole, SND 919CL2X

     An anti-apoptotic antioxidant Dexpramipexole dihydrochloride Chemical Structure
  85. GC71511 Dexpramipexole-d3 dihydrochloride Dexpramipexole-d3 (dihydrochloride) is the deuterium labeled Dexpramipexole. Dexpramipexole-d3 dihydrochloride Chemical Structure
  86. GC35864 Dihydrexidine Dihydrexidine (DAR-0100) is a high potent, selective and full efficacy D1-like dopamine receptor (D1/D5) agonist with an IC50 of 10 nM for D1 receptor. Dihydrexidine Chemical Structure
  87. GC10144 Domperidone

    KW 5338, NSC 299589

     Drug for gastroparesis Domperidone Chemical Structure
  88. GC71653 Domperidone monomaleate Domperidone (R33812) monomaleate is an orally active and selective dopamine-2 receptor antagonist. Domperidone monomaleate Chemical Structure
  89. GC62940 Dopamine

    DA, 3-hydroxy Tyramine, KW 3160, NSC 173182; 4-(2-Aminoethyl)benzene-1,2-diol

    Dopamine is a catecholamine neurotransmitter that is produced in the substantia nigra, ventral tegmental area, and hypothalamus of the brain.

     Dopamine Chemical Structure
  90. GC71157 Dopamine D2 receptor agonist-2 Dopamine D2 receptor agonist-2 (compound 36) is a potent dopamine D2 receptor biased agonism ligand with an Ki value of 11.2 nM. Dopamine D2 receptor agonist-2 Chemical Structure
  91. GC11028 Dopamine HCl

    DA, KW 3160, 3-hydroxy Tyramine

     Dopamine D1-5 receptors agonist Dopamine HCl Chemical Structure
  92. GC30772 Dopamine serotonin antagonist-1

    Deschloroclozapine

     Dopamine serotonin antagonist-1 Chemical Structure
  93. GC68997 Dopamine-d5 hydrochloride

    Dopamine-d5 (hydrochloride) is a deuterium-labeled form of Dopamine (hydrochloride). Dopamine hydrochloride (ASL279) is a catecholamine neurotransmitter produced in the substantia nigra, ventral tegmental area, and hypothalamus that plays an important role in the brain and body. Dopamine hydrochloride (ASL279) induces internalization of VEGFR2 through D2 dopamine receptor activation, which is crucial for promoting angiogenesis.

     Dopamine-d5 hydrochloride Chemical Structure
  94. GC10808 Droperidol

    DHBP, NSC 169874

     Dopamine-2 receptor antagonist Droperidol Chemical Structure
  95. GC12355 Eticlopride hydrochloride

    S-(-)-Eticlopride, (-)-Eticlopride

     dopamine D2/D3 receptor antagonist Eticlopride hydrochloride Chemical Structure
  96. GC39757 Etilevodopa hydrochloride Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa hydrochloride Chemical Structure
  97. GC70734 Fallypride Fallypride is a potent antagonist of dopamine D2/D3 receptor. Fallypride Chemical Structure
  98. GC73801 Fallypride precursor Fallypride precursor (Compound 15) can be used for synthesis of Fallypride. Fallypride precursor Chemical Structure
  99. GC13109 Fananserin 5-HT2A receptor antagonist Fananserin Chemical Structure
  100. GC62972 FAUC 346 FAUC 346, a highly selective D3 partial agonist (EC50 = 1.5 nM), also demonstrates an inhibitory effect on cocaine-seeking behavior. FAUC 346 Chemical Structure
  101. GC12466 FAUC-365 D3 dopamine receptor agonist FAUC-365 Chemical Structure

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