GLPBio

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products Related to Dopamine Receptor(300)

  • GC17760 structure
    GC17760Clozapine
    CAS: 5786-21-0
    Purity: >98.00%

    Clozapine is an antipsychotic agent that inhibits dopamine D2, muscarinic M1 receptor, and serotonin 5HT2A receptor with K i values of 75nM, 9.5nM, and 4nM, respectively.

  • GC17769 structure
    GC17769Sitaxentan sodium
    CAS: 210421-74-2
    Purity: >98.00%

    Sitaxentan sodium is a selective endothelin A receptor (ETA) antagonist (IC 50 = 1.4 nM; K i = 0.43nM).

  • GC10108 structure
    GC10108WAY-100635
    CAS: 162760-96-5
    Purity: >98.00%

    WAY-100635 is a highly potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC 50 value of 0.91nM and a K i value of 0.39nM.

  • GC10260 structure
    GC10260cis-Flupenthixol (hydrochloride)
    CAS: 51529-01-2
    Purity: >98%

    cis-Flupenthixol (hydrochloride) is a potent and selective DA D1/D2 receptor antagonist, with Ki values of 0.38 nM and 7 nM for D2 receptor and 5-HT2A, respectively.

  • GC10349 structure
    GC10349Sulpiride
    CAS: 15676-16-1
    Purity: >99.50%

    Sulpiride is a novel, orally active dopamine D2/D3 receptor antagonist, classified as a benzamide atypical antipsychotic drug.

  • GC10614 structure
    GC10614Rotigotine
    CAS: 99755-59-6
    Purity: >99.50%

    A non-selective dopamine receptor agonist

  • GC10643 structure
    GC10643Pimozide
    CAS: 2062-78-4
    Purity: >98.00%

    Pimozide is a chemically novel, highly potent and orally long-acting neuroleptic dopamine receptors inhibitor, with K i s of 2.4nM, 0.2nM and 1.8nM for dopamine D2, D3 and D4 receptors, respectively.

  • GC10745 structure
    GC10745Roxindole hydrochloride
    CAS: 108050-82-4
    Purity: >98%

    Dopamine D2 autoreceptor agonist

  • GC10799 structure
    GC10799Iloperidone hydrochloride
    CAS: 1299470-39-5
    Purity: >98%

    D(2)/5-HT(2) receptor antagonistis

  • GC10808 structure
    GC10808Droperidol
    CAS: 548-73-2
    Purity: >98.00%

    Dopamine-2 receptor antagonist

  • GC10822 structure
    GC10822Clozapine N-oxide (CNO)
    CAS: 34233-69-7
    Purity: >98.00%

    Clozapine N-oxide (CNO) is a ligand for the DREADD system used in chemogenetic research.

  • GC10892 structure
    GC10892SCH 23390 hydrochloride
    CAS: 125941-87-9
    Purity: >99.00%

    SCH 23390 hydrochloride is a potent and selective dopamine D1-like receptor antagonist that antagonizes D1/D5 receptors (K i =0.2nM, 0.3nM).

  • GC11020 structure
    GC11020Ziprasidone
    CAS: 146939-27-7
    Purity: >98.00%
  • GC11097 structure
    GC11097MPTP hydrochloride
    CAS: 23007-85-4
    Purity: >98.00%

    MPTP hydrochloride is a dopamine-neuronal toxin that can cross the blood-brain barrier (BBB) and damage neural functions.

  • GC11146 structure
    GC11146SKF 83959 hydrobromide
    CAS: 67287-95-0
    Purity: >99.50%

    Dopamine D1-like receptor partial agonist

  • GC11183 structure
    GC11183A 77636 hydrochloride
    CAS: 145307-34-2
    Purity: >99.50%

    A 77636 hydrochloride is a selective dopamine D1 receptor agonist with pK i =7.40±0.09; K i =39.8nM and EC 50 =1.1nM.

  • GC11243 structure
    GC11243Halopemide
    CAS: 59831-65-1
    Purity: >99.50%

    phospholipase D (PLD) inhibitor

  • GC11462 structure
    GC11462Ropinirole HCl
    CAS: 91374-20-8
    Purity: >99.50%

    Ropinirole (SKF 101468) hydrochloride is an orally active, potent D3/D2 receptor agonist with a Ki of 29 nM for D2 receptor.

  • GC11503 structure
    GC11503SKF 83822 hydrobromide
    CAS: 74115-10-9
    Purity: >98%

    dopamine D1-like receptor agonist

  • GC11521 structure
    GC11521Ziprasidone HCl
    CAS: 122883-93-6
    Purity: >98%

    Ziprasidone (CP-88059) hydrochloride is an orally active combined 5-HT and dopamine receptor antagonist.

  • GC11602 structure
    GC11602Piribedil dihydrochloride
    CAS: 1451048-94-4
    Purity: >98%

    dopamine agonist

  • GC11795 structure
    GC11795ABT 724 trihydrochloride
    CAS: 587870-77-7
    Purity: >99.00%

    Dopamine D4 receptor agonist,potent and selective

  • GC11810 structure
    GC11810PG 01037 dihydrochloride
    CAS: 675599-62-9
    Purity: >99.50%

    Dopamine D3 receptor antagonist

  • GC11902 structure
    GC11902PNU 96415E
    CAS: 170856-41-4
    Purity: >98%

    dopamine D4 and serotonergic 5-HT2A receptor antagonist