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Home >> Signaling Pathways >> Neuroscience >> Dopamine Receptor

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products for  Dopamine Receptor

  1. Cat.No. Product Name Information
  2. GC13853 GBR 12935 dihydrochloride dopamine reuptake inhibitor GBR 12935 dihydrochloride Chemical Structure
  3. GC12179 GBR 13069 dihydrochloride dopamine uptake inhibitor GBR 13069 dihydrochloride Chemical Structure
  4. GC41486 Glaucine Glaucine is an alkaloid originally isolated from G. Glaucine Chemical Structure
  5. GC38022 GR 103691 GR 103691 Chemical Structure
  6. GC16903 GR 103691 dopamine D3 receptor antagonist GR 103691 Chemical Structure
  7. GC14593 GSK 789472 hydrochloride dopamine D3 receptor antagonist and D2 partial agonist GSK 789472 hydrochloride Chemical Structure
  8. GC19176 GSK163090 GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist with pKi of 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3, respectively. GSK163090 Chemical Structure
  9. GC30241 GSK598809 GSK598809 is a potent and selective dopamine D3 Receptor (DRD3) antagonist, with a pKi of 8.9. GSK598809 Chemical Structure
  10. GC11243 Halopemide phospholipase D (PLD) inhibitor Halopemide Chemical Structure
  11. GC17599 Haloperidol Antipsychotic drug Haloperidol Chemical Structure
  12. GC36209 Haloperidol D4 Haloperidol D4 is deuterium labeled haloperidol, and the latter is a potent dopamine D2 receptor antagonist. Haloperidol D4 Chemical Structure
  13. GC36210 Haloperidol D4' Haloperidol D4' Chemical Structure
  14. GC11506 Haloperidol hydrochloride Antipsychotic drug Haloperidol hydrochloride Chemical Structure
  15. GC60915 Hydroxy ziprasidone Hydroxy ziprasidone is an impurity of Ziprasidone. Hydroxy ziprasidone Chemical Structure
  16. GC15463 Iloperidone Dopamine (D2) and serotonin (5HT2) receptor antagonist Iloperidone Chemical Structure
  17. GC10799 Iloperidone hydrochloride D(2)/5-HT(2) receptor antagonistis Iloperidone hydrochloride Chemical Structure
  18. GC17841 JHW 007 hydrochloride Dopamine uptake inhibitor JHW 007 hydrochloride Chemical Structure
  19. GC36370 JNJ-37822681 dihydrochloride JNJ-37822681 dihydrochloride is a potent, specific, centrally active, fast-dissociating dopamine D2 receptor antagonist with a moderate binding affinity for the dopamine D2L receptor (Ki =158 nM), which has potential for the treatment of schizophrenia and bipolar disorder. JNJ-37822681 dihydrochloride Chemical Structure
  20. GC60965 Keto Ziprasidone Keto Ziprasidone is an impurity of Ziprasidone. Keto Ziprasidone Chemical Structure
  21. GC15619 L-741,626 D2 dopamine receptor selective antagonist L-741,626 Chemical Structure
  22. GC13036 L-741,742 hydrochloride highly potent and selective D4 dopamine receptor antagonist L-741,742 hydrochloride Chemical Structure
  23. GC14569 L-745,870 trihydrochloride highly potent and selective D4 dopamine receptor antagonist L-745,870 trihydrochloride Chemical Structure
  24. GC38805 L-745870 L-745870 is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 Chemical Structure
  25. GC38806 L-745870 hydrochloride L-745870 hydrochloride is a potent, selective, brain-penetrant and orally active dopamine D4 receptor antagonist with a Ki of 0.43 nM. L-745870 hydrochloride Chemical Structure
  26. GC14281 L-DOPA methyl ester (hydrochloride) dopamine D1 receptor agonist L-DOPA methyl ester (hydrochloride) Chemical Structure
  27. GC17890 LE 300 dopamine D1 receptor antagonist LE 300 Chemical Structure
  28. GC15095 Levodopa Levodopa (Levodopa) is an orally active metabolic precursor of neurotransmitters dopamine. Levodopa Chemical Structure
  29. GC15470 Levosulpiride Antipsychotic drug Levosulpiride Chemical Structure
  30. GC16730 Lisuride maleate New Product Lisuride maleate Chemical Structure
  31. GC30797 lumateperone Tosylate (ITI-007) Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator. lumateperone Tosylate (ITI-007) Chemical Structure
  32. GC30926 Lurasidone (SM-13496) Lurasidone (SM-13496) (SM-13496) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone (SM-13496) Chemical Structure
  33. GC17593 Lurasidone HCl Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively. Lurasidone HCl Chemical Structure
  34. GC63052 LY3154207 LY3154207 is a potent, subtype selective, and orally available human dopamine D1 receptorpositive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM). LY3154207 Chemical Structure
  35. GC11182 LY404039 MGlu2 and mGlu3 receptors agonist LY404039 Chemical Structure
  36. GC63578 Medifoxamine Medifoxamine is a monoamine re-uptake inhibiting antidepressive drug which preferentially inhibits dopamine reuptake. Medifoxamine Chemical Structure
  37. GC63550 Mesdopetam hemitartrate Mesdopetam (IRL790) hemitartrate is a dopamine D3 receptor antagonist (Ki=90 nM; IC50=9.8 μM for human recombinant D3 receptor) with psychomotor stabilizing properties. Mesdopetam hemitartrate Chemical Structure
  38. GC16249 Metoclopramide Dopamine receptor antagonist Metoclopramide Chemical Structure
  39. GC36602 Metoclopramide hydrochloride hydrate Metoclopramide hydrochloride hydrate Chemical Structure
  40. GC45676 MLS-1547 An agonist of dopamine D2 receptors MLS-1547 Chemical Structure
  41. GC30904 Molindone hydrochloride (EN-1733A) Molindone hydrochloride (EN-1733A) (EN-1733A) is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses. Molindone hydrochloride (EN-1733A) Chemical Structure
  42. GC11097 MPTP hydrochloride

    MPTP (1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine) is a neurotoxic agent that is a precusor of MPP+ which is toxic to dopaminergic neurons and causes Parkinsonism.

     MPTP hydrochloride Chemical Structure
  43. GC65666 N-Methyldopamine hydrochloride N-Methyldopamine hydrochloride is a precursor of adrenaline in the adrenal medulla. N-Methyldopamine hydrochloride is a modification of the dopamine (DA), and retains agonist activity at the DA1 receptor. N-Methyldopamine hydrochloride remains capable of universal surface coating and secondary reactions using the surface catechols. N-Methyldopamine hydrochloride can be used for heart failure research. N-Methyldopamine hydrochloride Chemical Structure
  44. GC67705 Naxagolide Naxagolide Chemical Structure
  45. GC12543 Nemonapride dopamine D2-like receptor antagonist Nemonapride Chemical Structure
  46. GC31018 NEO 376 (SPI-376) NEO 376 (SPI-376) is a selective modulator of 5-HT1 receptor, GABA receptor and dopamine receptor, with anti-psychotic actively. NEO 376 (SPI-376) Chemical Structure
  47. GC36726 Neuromedin N Neuromedin N is a potent modulator of dopamine D2 receptor agonist binding in rat neostriatal membranes. Neuromedin N Chemical Structure
  48. GC18068 NGB 2904 NGB 2904 is a potent, selective, orally active and brain-penetrated antagonist of dopamine D3 receptor, with a Ki of 1.4 nM. NGB 2904 Chemical Structure
  49. GC14694 NGD 94-1 High affinity D4 receptor ligand NGD 94-1 Chemical Structure
  50. GC31111 NMI 8739 A conjugate of DHA and dopamine NMI 8739 Chemical Structure
  51. GC13573 Nomifensine noradrenalin and dopamine uptake inhibitor Nomifensine Chemical Structure
  52. GC64381 Nomifensine maleate Nomifensine maleate is a selective inhibitor of dopamine uptake, used in adult attention deficit disorder. Nomifensine maleate Chemical Structure
  53. GC17075 NPEC-caged-dopamine Dopamine receptor agonist NPEC-caged-dopamine Chemical Structure
  54. GC31015 NRA-0160 NRA-0160 is a selective dopamine D4 receptor antagonist, with a Ki value of 0.48 nM and with negligible affinity for dopamine D2 receptor (Ki: >10000 nM), D3 receptor (Ki: 39 nM), rat 5-HT2A receptor (Ki: 180 nM) and rat α1 adrenoceptor (Ki: 237 nM). NRA-0160 Chemical Structure
  55. GN10607 Nuciferine Nuciferine Chemical Structure
  56. GC31173 Ocaperidone (R79598) Ocaperidone (R79598) is an effective antipsychotic agent, acting as a potent 5-HT2 and dopamine D2 antagonist, and a 5-HT1A agonist, with Kis of 0.14 nM, 0.46 nM, 0.75 nM, 1.6 nM and 5.4 nM for 5-HT2, a1-adrenergic receptor, dopamine D2, histamine H1 and a2-adrenergic receptor, respectively, and a pEC50 and pKi of 7.60 and 8.08 for h5-HT1A. Ocaperidone (R79598) Chemical Structure
  57. GC38405 Odapipam Odapipam (NNC 756) is a selective, high affinity and benzazepine dopamine D1 receptor antagonist with a Kd of 0.18 nM. Odapipam Chemical Structure
  58. GC12495 Olanzapine Olanzapine (LY170053) is a selective, orally active monoaminergic antagonist with high affinity binding to serotonin H1, 5HT2A/2C, 5HT3, 5HT6 (Ki=7, 4, 11, 57, and 5 nM, respectively), dopamine D1-4 (Ki=11 to 31 nM), muscarinic M1-5 (Ki=1.9-25 nM), and adrenergic α1 receptor (Ki=19 nM). Olanzapine Chemical Structure
  59. GC61809 Olanzapine D3 Olanzapine D3 (LY170053-d3) is the deuterium labeled Olanzapine. Olanzapine D3 Chemical Structure
  60. GC38935 ONC206 ONC206 is an analogue of TRAIL inducer ONC201. ONC206 Chemical Structure
  61. GC33510 Org-10490 Org-10490 is an antagonist of dopamine D1 receptor and dopamine D2 receptor, used for the treatment for psychiatric disease. Org-10490 Chemical Structure
  62. GC69634 OS-3-106

    OS-3-106 is an effective and selective dopamine D3 receptor (D3R) agonist that can penetrate the blood-brain barrier. It has a high affinity for D3R (Ki = 0.2 nM). OS-3-106 can be used in research on stimulant addiction.

     OS-3-106 Chemical Structure
  63. GC17238 OSU 6162 hydrochloride Dopamine stabilizer OSU 6162 hydrochloride Chemical Structure
  64. GC30871 Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) Oxidopamine (6-OHDA) hydrochloride is an antagonist of the neurotransmitter dopamine. Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) Chemical Structure
  65. GC10112 Paliperidone Dopamine receptor antagonist Paliperidone Chemical Structure
  66. GC61167 Paliperidone palmitate Paliperidone palmitate (9-Hydroxyrisperidone palmitate), an atypical long-acting antipsychotic agent, is an ester prodrug of Paliperidone. Paliperidone palmitate Chemical Structure
  67. GC12800 PAOPA dopamine D2 receptor modulator PAOPA Chemical Structure
  68. GC31069 Pardoprunox (SLV-308) Pardoprunox (SLV-308) (SLV-308) is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively. Pardoprunox (SLV-308) Chemical Structure
  69. GC30980 Pardoprunox hydrochloride (SLV-308 hydrochloride) Pardoprunox (SLV-308) hydrochloride is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively. Pardoprunox hydrochloride (SLV-308 hydrochloride) Chemical Structure
  70. GC17634 PD 168077 maleate D4 dopamine receptor agonist PD 168077 maleate Chemical Structure
  71. GC14280 PD 168568 dihydrochloride dopamine D4 receptor antagonist PD 168568 dihydrochloride Chemical Structure
  72. GC17600 PD128907 HCl Potent and selective dopamine D3 receptor agonist PD128907 HCl Chemical Structure
  73. GC33730 Pentiapine (CGS 10746) Pentiapine (CGS 10746) (CGS 10746) is a dopamine release inhibitor without binding to synaptic dopamine receptor sites. Pentiapine (CGS 10746) Chemical Structure
  74. GC16615 Pergolide mesylate Dopaminergic agonist Pergolide mesylate Chemical Structure
  75. GC38231 Pericyazine A typical antipsychotic Pericyazine Chemical Structure
  76. GC39237 Perospirone Perospirone (SM-9018 free base) is an orally active antagonist of 5-HT2A receptor (Ki=0.6 nM) and dopamine D2 receptor (Ki=1.4 nM), and also a partial agonist of 5-HT1A receptor (Ki=2.9 nM). Perospirone Chemical Structure
  77. GC12293 Perphenazine dopamine antagonist Perphenazine Chemical Structure
  78. GC36875 Perphenazine D8 Dihydrochloride Perphenazine D8 Dihydrochloride is the deuterium labeled Perphenazine, which is a typical antipsychotic drug(5-HT, Dopamine receptor ligand). Perphenazine D8 Dihydrochloride Chemical Structure
  79. GC65343 PF-06256142 PF-06256142 is a potent, selective, CNS-penetrant and orally active agonist of the D1 receptor, with an EC50 and Ki of 33 nM and 12 nM, respectively. PF-06256142 Chemical Structure
  80. GC31225 PF-592379 PF-592379 is a potent dopamine D3 receptor agonist with an EC50 of 21 nM. PF-592379 Chemical Structure
  81. GC11810 PG 01037 dihydrochloride Dopamine D3 receptor antagonist PG 01037 dihydrochloride Chemical Structure
  82. GC10643 Pimozide dopamine receptors inhibitor Pimozide Chemical Structure
  83. GC45756 Pimozide-d4 An internal standard for the quantification of pimozide Pimozide-d4 Chemical Structure
  84. GC67752 Pimozide-d4-1 Pimozide-d4-1 Chemical Structure
  85. GC36924 Pipamperone Pipamperone (Floropipamide; McN-JR 3345; R 3345) is a high-affinity antagonist of 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0) and a low-affinity antagonist of D2 receptor (pKi=6.7). Pipamperone Chemical Structure
  86. GC31183 Piperidine-MO-1 Piperidine-MO-1 is a modulator of dopamine receptor extracted from patent WO/2005/121087A1, compound example 2; exhibits an ED50 of 68 μmol/kg on increase of DOPAC in the rat striatum. Piperidine-MO-1 Chemical Structure
  87. GC36929 Piribedil A dopamine receptor agonist Piribedil Chemical Structure
  88. GC30396 Piribedil D8 (ET-495 D8) Piribedil D8 (ET-495 D8) (ET-495 D8) is the deuterium labeled Piribedil, which is an antiparkinsonian agent. Piribedil D8 (ET-495 D8) Chemical Structure
  89. GC11602 Piribedil dihydrochloride dopamine agonist Piribedil dihydrochloride Chemical Structure
  90. GC15763 PNU 177864 hydrochloride dopamine D3 receptor antagonist PNU 177864 hydrochloride Chemical Structure
  91. GC11902 PNU 96415E dopamine D4 and serotonergic 5-HT2A receptor antagonist PNU 96415E Chemical Structure
  92. GC11960 Pramipexole Dopamine agonist Pramipexole Chemical Structure
  93. GC16783 Pramipexole 2HCl Monohydrate Pramipexole 2HCl Monohydrate is a selective and blood-brain barrier (BBB) penetrant dopamine D2-type receptor agonist, with Kis of 2.2 nM, 3.9 nM, 0.5 nM and 1.3 nM for D2-type receptor, D2, D3 and D4 receptors, respectively. Pramipexole 2HCl Monohydrate Chemical Structure
  94. GC13625 Pramipexole dihydrochloride A dopamine D2S, D2L, D3, and D4 receptor agonist Pramipexole dihydrochloride Chemical Structure
  95. GC30854 Pridopidine (ACR16) Pridopidine (ACR16), a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist. Pridopidine (ACR16) Chemical Structure
  96. GC30974 Promazine hydrochloride Promazine hydrochloride Chemical Structure
  97. GC68206 Propionylpromazine Propionylpromazine Chemical Structure
  98. GC39736 Propionylpromazine hydrochloride Propionylpromazine hydrochloride (Propiopromazine hydrochloride), a dopamine receptor D2 (DRD2) antagonist, can be used in the research of Parkinson disease. Propionylpromazine hydrochloride Chemical Structure
  99. GC68420 Propionylpromazine-d6 hydrochloride Propionylpromazine-d6 hydrochloride Chemical Structure
  100. GC63157 PW0464 PW0464, a nanomolar potent complete G protein biased ligand, is a noncatechol D1R agonist, with an EC50 of 5.8 nM (Gs-cAMP). PW0464 Chemical Structure
  101. GC14167 Quetiapine Quetiapine Chemical Structure

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