GLPBio

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products Related to Dopamine Receptor(300)

  • GC17047 structure
    GC17047Threo-methylphenidate hydrochloride
    CAS: 298-59-9
    Purity: >98.00%

    Threo-methylphenidate hydrochloride is a catecholamine reuptake inhibitor that inhibits dopamine transporter (DAT) and norepinephrine transporter (NET)[1].

  • GC17075 structure
    GC17075NPEC-caged-dopamine
    CAS: 1257326-23-0
    Purity: >99.00%

    Dopamine receptor agonist

  • GC17192 structure
    GC17192Quinelorane hydrochloride
    CAS: 97548-97-5
    Purity: >98%

    Quinelorane hydrochloride (LY163502) is a potent dopamine D3/D2 receptor agonist.

  • GC17238 structure
    GC17238OSU 6162 hydrochloride
    CAS: 156907-84-5
    Purity: >98%

    Dopamine stabilizer

  • GC17527 structure
    GC17527(+)-Dihydrexidine hydrochloride
    CAS: 158704-02-0
    Purity: >98.50%

    (+)-Dihydrexidine hydrochloride ((+)-DAR-0100 hydrochloride) is a dopamine D1 receptor agonist with an EC50 of 72± 21 nM.

  • GC17593 structure
    GC17593Lurasidone HCl
    CAS: 367514-88-3
    Purity: >98.00%

    Lurasidone (Hydrochloride) (SM-13496 (Hydrochloride)) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively.

  • GC17634 structure
    GC17634PD 168077 maleate
    CAS: 630117-19-0
    Purity: >98.50%

    D4 dopamine receptor agonist

  • GC17656 structure
    GC17656Chlorprothixene (hydrochloride)
    CAS: 6469-93-8
    Purity: >98.00%

    dopamine D2 receptor antagonist and GABAA receptor inhibitor

  • GC17729 structure
    GC17729SKF38393 HCl
    CAS: 62717-42-4
    Purity: >99.00%

    SKF38393 HCl is a selective agonist of the dopamine D1 receptor (D1DR) with an IC50 of 110 nM.

  • GC17841 structure
    GC17841JHW 007 hydrochloride
    CAS: 202645-74-7
    Purity: >98%

    Dopamine uptake inhibitor

  • GC17877 structure
    GC17877(-)-Quinpirole hydrochloride
    CAS: 85798-08-9
    Purity: >99.00%

    dopamine D2 receptor agonist

  • GC17890 structure
    GC17890LE 300
    CAS: 274694-98-3
    Purity: >98%

    dopamine D1 receptor antagonist

  • GC18068 structure
    GC18068NGB 2904
    CAS: 189060-98-8
    Purity: >98.00%

    NGB 2904 is a potent, selective, orally active and brain-penetrated antagonist of dopamine D3 receptor, with a Ki of 1.4 nM.

  • GC19176 structure
    GC19176GSK163090
    CAS: 844903-58-8
    Purity: >99.50%

    GSK163090 is a potent, selective, and orally active 5-HT1A/B/D receptor antagonist with pKi of 9.4/8.5/9.7, and 6.3/6.7 for 5-HT1A/B/D, and dopamine D2/D3, respectively.

  • GC19499 structure
    GC19499A-381393
    CAS: 726174-00-1
    Purity: >99.50%

    A-381393 is a potent, selective, brain penetrate dopamine D4 receptor antagonist

  • GC26387 structure
    GC26387Apomorphine hydrochloride hemihydrate
    CAS: 41372-20-7
    Purity: >98.00%

    Apomorphine hydrochloride hemihydrate is a dopamine D2 agonist. Apomorphine hydrochloride hemihydrate can stimulate dopamine receptors in the nigrostriatal system, hypothalamus, limbic system, pituitary gland and blood vessels, thereby enhancing motor function, inhibiting prolactin release, and causing vasodilation and behavioral dysfunction. Apomorphine hydrochloride hemihydrate is mainly used to treat Parkinson's disease and male erectile dysfunction.

  • GC30241 structure
    GC30241GSK598809
    CAS: 863680-45-9
    Purity: >99.50%

    GSK598809 is a potent and selective dopamine D3 Receptor (DRD3) antagonist, with a pKi of 8.9.

  • GC30280 structure
    GC30280Chlorpromazine D6 hydrochloride
    CAS: 1228182-46-4
    Purity: >99.50%

    Chlorpromazine D6 hydrochloride is a deuterated form of Chlorpromazine and can be used as an internal standard in NMR, GC-MS, or LC-MS analyses for quantitative analysis.

  • GC30375 structure
    GC30375Clomipramine D3
    CAS: 136765-29-2
    Purity: >98%

    Clomipramine D3 (Chlorimipramine-d3) is the deuterium labeled Clomipramine.

  • GC30396 structure
    GC30396Piribedil D8 (ET-495 D8)
    CAS: 1398044-45-5
    Purity: >98%

    Piribedil D8 (ET-495 D8) (ET-495 D8) is the deuterium labeled Piribedil, which is an antiparkinsonian agent.

  • GC30772 structure
    GC30772Dopamine serotonin antagonist-1
    CAS: 1977-07-7
    Purity: >98%
  • GC30787 structure
    GC30787Sertindole (Lu 23-174)
    CAS: 106516-24-9
    Purity: >99.50%

    Sertindole (Lu 23-174) (Lu 23-174) is an orally active 5-HT2A, 5-HT2C, dopamine D2, and αl-adrenergic receptors antagonist.

  • GC30790 structure
    GC30790Triflupromazine hydrochloride
    CAS: 1098-60-8
    Purity: >99.50%

    A phenothiazine with diverse biological activities

  • GC30797 structure
    GC30797lumateperone Tosylate (ITI-007)
    CAS: 1187020-80-9
    Purity: >99.00%

    Lumateperone (ITI-007) tosylate is a 5-HT2A receptor antagonist (Ki = 0.54 nM), a partial agonist of presynaptic D2 receptors and an antagonist of postsynaptic D2 receptors (Ki = 32 nM), and a dopamine D1 receptor modulator.