GLPBio

Dopamine Receptor

Dopamine receptors (DR) are members of G protein-coupled receptors superfamily. There are 5 subtypes (D1, D2, D3, D4, D5) of DR which mediate the functions of dopamine in central nervous system for control of locomotion, cognition, and emotion etc.

Products Related to Dopamine Receptor(300)

  • GC30824 structure
    GC30824Veralipride ((±)-Veralipride)
    CAS: 66644-81-3
    Purity: >99.50%

    Veralipride ((±)-Veralipride) is a D2 receptor antagonist.

  • GC30840 structure
    GC30840Quinagolide hydrochloride (CV205-502 hydrochloride)
    CAS: 94424-50-7
    Purity: >98%

    Quinagolide hydrochloride (CV205-502 hydrochloride) is a selective dopamine D2 receptor agonist, also is a prolactin inhibitor.

  • GC30848 structure
    GC30848(+)-PD 128907 hydrochloride
    CAS: 300576-59-4
    Purity: >98.00%

    A potent D 3 receptor agonist

  • GC30854 structure
    GC30854Pridopidine (ACR16)
    CAS: 346688-38-8
    Purity: >99.50%

    Pridopidine (ACR16), a dopamine (DA) stabilizer, acts as a low affinity dopamine D2 receptor (D2R) antagonist.

  • GC30871 structure
    GC30871Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride)
    CAS: 28094-15-7
    Purity: >97.00%

    Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) (6-OHDA) is an antagonist of the neurotransmitter dopamine.

  • GC30904 structure
    GC30904Molindone hydrochloride (EN-1733A)
    CAS: 15622-65-8
    Purity: >99.50%

    Molindone hydrochloride (EN-1733A) (EN-1733A) is a therapeutic antipsychotic, used in the treatment of schizophrenia, works by blocking the effects of dopamine in the brain, leading to diminished psychoses.

  • GC30926 structure
    GC30926Lurasidone (SM-13496)
    CAS: 367514-87-2
    Purity: >99.50%

    Lurasidone (SM-13496) (SM-13496) is an antagonist of both dopamine D2 and 5-HT7 with IC50s of 1.68 and 0.495 nM, respectively.

  • GC30944 structure
    GC30944Sultopride hydrochloride (LIN-1418 hydrochloride)
    CAS: 23694-17-9
    Purity: >98.00%

    Sultopride hydrochloride (LIN-1418 hydrochloride) (LIN-1418 hydrochloride) is a selective antagonist of dopamine D2 receptor.

  • GC30974 structure
    GC30974Promazine hydrochloride
    CAS: 53-60-1
    Purity: >99.00%
  • GC30975 structure
    GC30975Tiapride hydrochloride
    CAS: 51012-33-0
    Purity: >99.00%

    Tiapride hydrochloride is a selective and orally active D2 and D3 dopamine receptors antagonist with IC50 values of 110-320 nM and 180 nM, respectively.

  • GC30980 structure
    GC30980Pardoprunox hydrochloride (SLV-308 hydrochloride)
    CAS: 269718-83-4
    Purity: >98.00%

    Pardoprunox (SLV-308) hydrochloride is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively.

  • GC30995 structure
    GC30995CGP 25454A
    CAS: 104391-26-6
    Purity: >99.00%

    CGP 25454A is a novel and selective presynaptic dopamine autoreceptor antagonist.

  • GC31015 structure
    GC31015NRA-0160
    CAS: 204718-47-8
    Purity: >98%

    NRA-0160 is a selective dopamine D4 receptor antagonist, with a Ki value of 0.48 nM and with negligible affinity for dopamine D2 receptor (Ki: >10000 nM), D3 receptor (Ki: 39 nM), rat 5-HT2A receptor (Ki: 180 nM) and rat α1 adrenoceptor (Ki: 237 nM).

  • GC31018 structure
    GC31018NEO 376 (SPI-376)
    CAS: 496921-73-4
    Purity: >98%

    NEO 376 (SPI-376) is a selective modulator of 5-HT1 receptor, GABA receptor and dopamine receptor, with anti-psychotic actively.

  • GC31037 structure
    GC31037Clocapramine (Clocarpramine)
    CAS: 47739-98-0
    Purity: >98%
  • GC31047 structure
    GC31047Bromopride
    CAS: 4093-35-0
    Purity: >98%

    A dopamine D 2 receptor antagonist

  • GC31055 structure
    GC31055Abaperidone
    CAS: 183849-43-6
    Purity: >98%

    Abaperidone is a potent antagonist of 5-HT2A?receptor and dopamine D2 receptor with IC50s of 6.2 and 17 nM.

  • GC31069 structure
    GC31069Pardoprunox (SLV-308)
    CAS: 269718-84-5
    Purity: >98%

    Pardoprunox (SLV-308) (SLV-308) is a partial dopamine D2 and D3 receptor partial agonist and a serotonin 5-HT1A receptor agonist, with pEC50s of 8, 9.2, and 6.3, respectively.

  • GC31111 structure
    GC31111NMI 8739
    CAS: 129024-87-9
    Purity: >98%

    A conjugate of DHA and dopamine

  • GC31173 structure
    GC31173Ocaperidone (R79598)
    CAS: 129029-23-8
    Purity: >99.50%

    Ocaperidone (R79598) is an effective antipsychotic agent, acting as a potent 5-HT2 and dopamine D2 antagonist, and a 5-HT1A agonist, with Kis of 0.14 nM, 0.46 nM, 0.75 nM, 1.6 nM and 5.4 nM for 5-HT2, a1-adrenergic receptor, dopamine D2, histamine H1 and a2-adrenergic receptor, respectively, and a pEC50 and pKi of 7.60 and 8.08 for h5-HT1A.

  • GC31183 structure
    GC31183Piperidine-MO-1
    CAS: 871351-61-0
    Purity: >98%

    Piperidine-MO-1 is a modulator of dopamine receptor extracted from patent WO/2005/121087A1, compound example 2; exhibits an ED50 of 68 μmol/kg on increase of DOPAC in the rat striatum.

  • GC31188 structure
    GC31188Sultopride (LIN-1418)
    CAS: 53583-79-2
    Purity: >98%

    Sultopride (LIN-1418) (LIN-1418) is a selective antagonist of dopamine D2 receptor.

  • GC31214 structure
    GC31214A-437203 (Lu201640)
    CAS: 220519-06-2
    Purity: >98%

    A-437203 (Lu201640) is a selective D3 receptor antagonist with Ki of 71, 1.6, and 6220 nM for D2, D3, and D4 receptors, respectively.

  • GC31225 structure
    GC31225PF-592379
    CAS: 710655-15-5
    Purity: >98%

    PF-592379 is a potent dopamine D3 receptor agonist with an EC50 of 21 nM.