FXR & LXR
FXR (farnesoid X receptor) is a nuclear receptor that binds to hormone response elements on DNA, regulating the expression of certain genes when it is activated.
Products Related to FXR & LXR(82)
- GC79659Deoxycholic acid 3-O-β-D-glucuronide disodiumCAS: 59274-67-8Purity: >99.50%
Deoxycholic Acid 3-O-beta-D-Glucuronide disodium salt is a bile acid receptor ( FXR ) agonist.
- GC79765Ginsenoside C-K hexapropionate esterCAS: 2861254-89-7Purity: >98.50%
Ginsenoside C-K hexapropionate ester (Structure 2) is a selective agonist of LXRα, with no significant activation effect on LXRβ. Ginsenoside C-K hexapropionate ester upregulates the expression of downstream genes such as ABCA1 by activating LXRα, promoting reverse cholesterol transport, and reducing lipid deposition in macrophage-derived foam cells.
- GC81689Teduglutide-Leu( 13 C 6 , 15 N) sodiumPurity: >96.50%
Teduglutide -Leu( 13 C 6, 15 N) (ALX-0600-Leu( 13 C 6, 15 N)) sodium is the 13 C- and 15 N-labeled Teduglutide.
- GC91042Tauro-Obeticholic Acid (sodium salt)CAS: 2278141-79-8Purity: >98.00%
An active metabolite of obeticholic acid
- GC916804-Acetamido AntipyrineCAS: 83-15-8Purity: >95.00%
4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC79659 | Deoxycholic acid 3-O-β-D-glucuronide disodium | 59274-67-8 | >99.50% | |
Deoxycholic Acid 3-O-beta-D-Glucuronide disodium salt is a bile acid receptor ( FXR ) agonist. | ||||
| GC79763 | TLC-2716 | 2408041-54-1 | >98% | |
TLC-2716 is an orally available, gut- and liver-restricted inhibitor against LXRα and LXRβ, with EC 50 values of 7 nM and 15 nM, respectively. | ||||
| GC79765 | Ginsenoside C-K hexapropionate ester | 2861254-89-7 | >98.50% | |
Ginsenoside C-K hexapropionate ester (Structure 2) is a selective agonist of LXRα, with no significant activation effect on LXRβ. Ginsenoside C-K hexapropionate ester upregulates the expression of downstream genes such as ABCA1 by activating LXRα, promoting reverse cholesterol transport, and reducing lipid deposition in macrophage-derived foam cells. | ||||
| GC81689 | Teduglutide-Leu( 13 C 6 , 15 N) sodium | - | >96.50% | |
Teduglutide -Leu( 13 C 6, 15 N) (ALX-0600-Leu( 13 C 6, 15 N)) sodium is the 13 C- and 15 N-labeled Teduglutide. | ||||
| GC90700 | Dendrogenin A | 1191043-85-2 | >95.00% | |
A selective LXR modulator and ChEH inhibitor | ||||
| GC91037 | ZLY28 | 3004676-77-8 | >90.00% | |
An FXR agonist and inhibitor of FABP1 | ||||
| GC91042 | Tauro-Obeticholic Acid (sodium salt) | 2278141-79-8 | >98.00% | |
An active metabolite of obeticholic acid | ||||
| GC91680 | 4-Acetamido Antipyrine | 83-15-8 | >95.00% | |
4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole . | ||||
| GC92033 | HPG1860 | 2226133-29-3 | >98.00% | |
HPG1860 is a farnesoid X receptor (FXR) agonist. | ||||
| GN10024 | Saikosaponin A | 20736-09-8 | >99.00% | |
