GLPBio

FXR & LXR

FXR (farnesoid X receptor) is a nuclear receptor that binds to hormone response elements on DNA, regulating the expression of certain genes when it is activated.

Products Related to FXR & LXR(82)

  • GC79659 structure
    GC79659Deoxycholic acid 3-O-β-D-glucuronide disodium
    CAS: 59274-67-8
    Purity: >99.50%

    Deoxycholic Acid 3-O-beta-D-Glucuronide disodium salt is a bile acid receptor ( FXR ) agonist.

  • GC79763 structure
    GC79763TLC-2716
    CAS: 2408041-54-1
    Purity: >98%

    TLC-2716 is an orally available, gut- and liver-restricted inhibitor against LXRα and LXRβ, with EC 50 values of 7 nM and 15 nM, respectively.

  • GC79765 structure
    GC79765Ginsenoside C-K hexapropionate ester
    CAS: 2861254-89-7
    Purity: >98.50%

    Ginsenoside C-K hexapropionate ester (Structure 2) is a selective agonist of LXRα, with no significant activation effect on LXRβ. Ginsenoside C-K hexapropionate ester upregulates the expression of downstream genes such as ABCA1 by activating LXRα, promoting reverse cholesterol transport, and reducing lipid deposition in macrophage-derived foam cells.

  • GC81689 structure
    GC81689Teduglutide-Leu( 13 C 6 , 15 N) sodium
    Purity: >96.50%

    Teduglutide -Leu( 13 C 6, 15 N) (ALX-0600-Leu( 13 C 6, 15 N)) sodium is the 13 C- and 15 N-labeled Teduglutide.

  • GC90700 structure
    GC90700Dendrogenin A
    CAS: 1191043-85-2
    Purity: >95.00%

    A selective LXR modulator and ChEH inhibitor

  • GC91037 structure
    GC91037ZLY28
    CAS: 3004676-77-8
    Purity: >90.00%

    An FXR agonist and inhibitor of FABP1

  • GC91042 structure
    GC91042Tauro-Obeticholic Acid (sodium salt)
    CAS: 2278141-79-8
    Purity: >98.00%

    An active metabolite of obeticholic acid

  • GC91680 structure
    GC916804-Acetamido Antipyrine
    CAS: 83-15-8
    Purity: >95.00%

    4-Acetamido antipyrine (4-AAAP) is an active metabolite of the non-opioid analgesic and antipyretic prodrug metamizole .

  • GC92033 structure
    GC92033HPG1860
    CAS: 2226133-29-3
    Purity: >98.00%

    HPG1860 is a farnesoid X receptor (FXR) agonist.

  • GN10024 structure
    GN10024Saikosaponin A
    CAS: 20736-09-8
    Purity: >99.00%