Neuropeptide FF/AF Receptors
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Neuropeptide Y receptors are a class of G-protein coupled receptors which are activated by the closely related peptide hormones neuropeptide Y, peptide YY and pancreatic polypeptide. These receptors are involved in the control of a diverse set of behavioral processes including appetite, circadian rhythm, and anxiety.
Neuropeptide Y (NPY) is a potent orexigenic neuropeptide, and antagonism of NPY Y1 and NPY Y5 receptors (NPYxR) is considered a potentially important anti-obesity drug target.
Neuropeptide Y (NPY) is widely distributed in the human body and contributes to a vast number of physiological processes. A number of other uses for modulators of NPY receptors have been implied in a range of diseases.
Products Related to Neuropeptide FF/AF Receptors(51)
- GC31154Neuropeptide Y (13-36), amide, human (Neuropeptide Y (13-36), human)CAS: 122341-40-6Purity: >98.50%
Neuropeptide Y (13-36), amide, human (Neuropeptide Y (13-36), human) is a selectiveneuropeptide Y2 receptoragonist.
- GC31161Neuropeptide Y(29-64)CAS: 303052-45-1Purity: >98.00%
Neuropeptide Y(29-64) is a 36 amino acid peptide, a fragment of Neuropeptide Y.
- GC31165Neuropeptide Y (29-64), amide, humanCAS: 90880-35-6Purity: >98%
Neuropeptide Y (29-64), amide, human, a 36-aa peptide, binds to five G-protein-coupled receptors (Y1, Y2, Y4, Y5, and y6).
- GC31338Velneperit (S2367)CAS: 342577-38-2Purity: >99.50%
Velneperit (S2367) (S-2367) is a novel neuropeptide Y (NPY) Y5 receptor antagonist.
- GC33785Pancreatic Polypeptide, rat (Rat pancreatic polypeptide)CAS: 90419-12-8Purity: >98%
Pancreatic Polypeptide, rat (Rat pancreatic polypeptide) is an agonist of NPY receptor, with high affinity at NPYR4.
- GC34222Galanin (1-16), mouse, porcine, rat TFAPurity: >99.00%
Galanin (1-16), mouse, porcine, rat (TFA) is an agonist of the hippocampal galanin receptor, with a Kd of 3 nM.
- GC36102Galanin Receptor Ligand M35CAS: 142846-71-7Purity: >98.00%
Galanin Receptor Ligand M35 is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 nM).
- GC36728Neuropeptide Y 22-36CAS: 119019-65-7Purity: >98%
Neuropeptide Y 22-36, a 15 amino acid peptide, is a fragment of Neuropeptide Y.
- GC60322RF9 hydrochloridePurity: >99.00%
RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist, with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively.
- GC61499Neuropeptide Y (human) (TFA)Purity: >98.50%
Neuropeptide Y (human) TFA is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.
- GC61530BIBO3304 TFACAS: 191868-14-1Purity: >98.00%
BIBO3304 TFA has subnanomolar affinity for both the human and the rat neuropeptide Y (NPY) Y1 receptor with IC50 values of 0.38±0.06 nM and 0.72±0.42 nM, respectively.
- GC61875Neuropeptide Y (3-36) (human, rat)CAS: 150138-78-6Purity: >95.00%
Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist.
- GC63855Peptide YY (PYY) (3-36), porcine TFAPurity: >99.00%
Peptide YY (PYY) (3-36), porcine TFA is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite.
- GC69142Galanin (1-29)(rat, mouse) TFAPurity: >98%
Galanin (1-29) (rat, mouse) TFA is a non-selective agonist of galanin receptors, with Ki values of 0.98 nM for GAL1, 1.48 nM for GAL2 and 1.47 nM for GAL3. It has anticonvulsant effects.
- GC69143Galantide TFAPurity: >98.00%
Galantide TFA is a reversible, non-specific antagonist of galanin (GAL) receptors. It shows dose-dependent antagonistic effects on GAL-induced K+ conductance with an IC50 value of 4 nM. Galantide TFA can be used for research in neurological disorders and hormone metabolism.
- GC72092Neuropeptide Y (human,rat,mouse) (TFA)Purity: >98.00%
Neuropeptide Y (human) TFA is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.
- GC72118[Leu31,Pro34]-Neuropeptide Y(human,rat,mouse) TFAPurity: >98.00%
[Leu31,Pro34]-Neuropeptide Y(human,rat,mouse) TFA is a modified, selective neuropeptide Y Y1 receptor agonist.
- GC72210(Leu31,Pro34)-Peptide YY (human) (TFA)Purity: >99.00%
(Leu31,Pro34)-Peptide YY (human) (TFA) is the TFA form of (Leu31,Pro34)-Peptide YY (human) .
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC31154 | Neuropeptide Y (13-36), amide, human (Neuropeptide Y (13-36), human) | 122341-40-6 | >98.50% | |
Neuropeptide Y (13-36), amide, human (Neuropeptide Y (13-36), human) is a selectiveneuropeptide Y2 receptoragonist. | ||||
| GC31161 | Neuropeptide Y(29-64) | 303052-45-1 | >98.00% | |
Neuropeptide Y(29-64) is a 36 amino acid peptide, a fragment of Neuropeptide Y. | ||||
| GC31165 | Neuropeptide Y (29-64), amide, human | 90880-35-6 | >98% | |
Neuropeptide Y (29-64), amide, human, a 36-aa peptide, binds to five G-protein-coupled receptors (Y1, Y2, Y4, Y5, and y6). | ||||
| GC31335 | MK-0557 | 328232-95-7 | >99.50% | |
An antagonist of NYP receptor Y 5 | ||||
| GC31338 | Velneperit (S2367) | 342577-38-2 | >99.50% | |
Velneperit (S2367) (S-2367) is a novel neuropeptide Y (NPY) Y5 receptor antagonist. | ||||
| GC33785 | Pancreatic Polypeptide, rat (Rat pancreatic polypeptide) | 90419-12-8 | >98% | |
Pancreatic Polypeptide, rat (Rat pancreatic polypeptide) is an agonist of NPY receptor, with high affinity at NPYR4. | ||||
| GC34222 | Galanin (1-16), mouse, porcine, rat TFA | - | >99.00% | |
Galanin (1-16), mouse, porcine, rat (TFA) is an agonist of the hippocampal galanin receptor, with a Kd of 3 nM. | ||||
| GC34270 | Neuropeptide Y (29-64), amide, human TFA | - | >98% | |
| GC36102 | Galanin Receptor Ligand M35 | 142846-71-7 | >98.00% | |
Galanin Receptor Ligand M35 is a high-affinity ligand and antagonist of galanin receptor (Kd=0.1 nM). | ||||
| GC36261 | HT-2157 | 303149-14-6 | >98.00% | |
A GAL 3 receptor antagonist | ||||
| GC36728 | Neuropeptide Y 22-36 | 119019-65-7 | >98% | |
Neuropeptide Y 22-36, a 15 amino acid peptide, is a fragment of Neuropeptide Y. | ||||
| GC60322 | RF9 hydrochloride | - | >99.00% | |
RF9 hydrochloride is a potent and selective Neuropeptide FF receptor antagonist, with Ki values of 58 and 75 nM for hNPFF1R and hNPFF2R, respectively. | ||||
| GC61499 | Neuropeptide Y (human) (TFA) | - | >98.50% | |
Neuropeptide Y (human) TFA is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity. | ||||
| GC61530 | BIBO3304 TFA | 191868-14-1 | >98.00% | |
BIBO3304 TFA has subnanomolar affinity for both the human and the rat neuropeptide Y (NPY) Y1 receptor with IC50 values of 0.38±0.06 nM and 0.72±0.42 nM, respectively. | ||||
| GC61875 | Neuropeptide Y (3-36) (human, rat) | 150138-78-6 | >95.00% | |
Neuropeptide Y (3-36) (human, rat), a neuropeptide Y (NPY) metabolite formed from dipeptidyl peptidase-4 (DPP4), is a selective Y2 receptor agonist. | ||||
| GC63855 | Peptide YY (PYY) (3-36), porcine TFA | - | >99.00% | |
Peptide YY (PYY) (3-36), porcine TFA is a gut hormone peptide that acts as a Y2 receptor agonist to reduce appetite. | ||||
| GC69142 | Galanin (1-29)(rat, mouse) TFA | - | >98% | |
Galanin (1-29) (rat, mouse) TFA is a non-selective agonist of galanin receptors, with Ki values of 0.98 nM for GAL1, 1.48 nM for GAL2 and 1.47 nM for GAL3. It has anticonvulsant effects. | ||||
| GC69143 | Galantide TFA | - | >98.00% | |
Galantide TFA is a reversible, non-specific antagonist of galanin (GAL) receptors. It shows dose-dependent antagonistic effects on GAL-induced K+ conductance with an IC50 value of 4 nM. Galantide TFA can be used for research in neurological disorders and hormone metabolism. | ||||
| GC69201 | GW438014A | 469861-49-2 | >99.00% | |
GW438014A is an effective selective NPY-Y5 receptor antagonist. It inhibits food intake and reduces weight gain in obese rodents. | ||||
| GC70657 | SF-22 | 824981-55-7 | >99.00% | |
SF-22 is a potent and brain-penetrant antagonist of neuropeptide Y receptor (Y2R), with the IC50 value of 750 nM. | ||||
| GC72092 | Neuropeptide Y (human,rat,mouse) (TFA) | - | >98.00% | |
Neuropeptide Y (human) TFA is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity. | ||||
| GC72108 | M40 TFA | - | - | |
M40 TFA is the TFA salt form of M40. | ||||
| GC72118 | [Leu31,Pro34]-Neuropeptide Y(human,rat,mouse) TFA | - | >98.00% | |
[Leu31,Pro34]-Neuropeptide Y(human,rat,mouse) TFA is a modified, selective neuropeptide Y Y1 receptor agonist. | ||||
| GC72210 | (Leu31,Pro34)-Peptide YY (human) (TFA) | - | >99.00% | |
(Leu31,Pro34)-Peptide YY (human) (TFA) is the TFA form of (Leu31,Pro34)-Peptide YY (human) . | ||||