Neuropeptide Y (13-36), amide, human (Neuropeptide Y (13-36), human) (Synonyms: Neuropeptide Y (13-36), human) |
| Catalog No.GC31154 |
Neuropeptide Y (13-36), amide, human (Neuropeptide Y (13-36), human) is a selectiveneuropeptide Y2 receptoragonist.
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Cas No.: 122341-40-6
Sample solution is provided at 25 µL, 10mM.
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Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.
Intraventricular injections of the Y2 neuropeptide Y receptor agonist porcine Neuropeptide Y (13-36) (25-3000 pM) produces a dose-dependent increase (up to 14%; ED50=0.3 nM for overall effects and 0.97 nM for the peak effects) in mean arterial blood pressure in the awake, unrestrains male rat without affecting heart rate. Central administration of porcine Neuropeptide Y (13-36) produces marked vasodepressor and bradycardic actions in the anaesthetized α-chloralose and in the awake unrestrained male rat[1].
[1]. Aguirre JA, et al. Centrally injected neuropeptide Y (13-36) produces vasopressor effects and antagonizes the vasodepressor action of neuropeptide Y (1-36) in the awake male rat. Neurosci Lett. 1990 Oct 2;118(1):5-8.
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