GLPBio

Prostaglandin Receptor

Prostaglandin receptors are a group of g-protein coupled receptor that exhibited a variety of functions in regulation of blood pressure and renal function; smooth muscle contraction; inhibition of plate aggregation; immune response etc.

Products Related to Prostaglandin Receptor(174)

  • GC17348 structure
    GC17348BW A868C
    CAS: 118675-50-6
    Purity: >98.00%

    prostaglandin D2 antagonist

  • GC17367 structure
    GC17367Rebamipide
    CAS: 90098-04-7
    Purity: >99.50%

    cholecystokinin type 1 (CCK1) receptor inhibitor

  • GC17410 structure
    GC17410S18886
    CAS: 165538-40-9
    Purity: >98.00%

    S18886 is a thromboxane-prostaglandin receptor antagonist.

  • GC17719 structure
    GC177195-trans U-46619
    CAS: 330796-58-2
    Purity: >98%

    Prostaglandin E synthase inhibitor

  • GC17861 structure
    GC17861Sulprostone
    CAS: 60325-46-4
    Purity: >98.00%

    EP3 and EP1 receptor agonist

  • GC18111 structure
    GC18111Seratrodast
    CAS: 112665-43-7
    Purity: >98.00%

    thromboxane A2 (TXA2) receptor (TP) antagonist

  • GC18132 structure
    GC18132U-44069
    CAS: 56985-32-1
    Purity: >98%

    TP receptor agonist

  • GC18318 structure
    GC18318CAY10441
    CAS: 221529-58-4
    Purity: >98.00%

    CAY10441 is a potent and selective IP (prostacyclin) receptor antagonist.

  • GC18678 structure
    GC18678CAY10595
    CAS: 916047-16-0
    Purity: >98%

    The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2.

  • GC19147 structure
    GC19147Evatanepag
    CAS: 223488-57-1
    Purity: >99.00%

    Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM.

  • GC19153 structure
    GC19153Fevipiprant
    CAS: 872365-14-5
    Purity: >99.50%

    Fevipiprant(QAW039) is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood.

  • GC19327 structure
    GC19327Setipiprant
    CAS: 866460-33-5
    Purity: >98.00%

    Setipiprant is a selective and orally available prostaglandin D2 receptor 2 (DP2, also known as CRTH2) antagonist, which is a γ-carboline derivative with an IC₅₀ of 6nM.

  • GC19354 structure
    GC19354TG6-10-1
    CAS: 1415716-58-3
    Purity: >99.50%

    TG6-10-1 is an EP2 antagonist, shows low-nanomolar antagonist activity against only EP2, >300-fold selectivity over human EP3, EP4, and IP receptors, 100-fold selectivity over EP1 receptors.

  • GC19395 structure
    GC19395MK-7246
    CAS: 1218918-62-7
    Purity: >98.50%

    MK-7246 is a potent and selective CRTH2 antagonist with a Ki of 2.5±0.5 nM.

  • GC30068 structure
    GC30068Taprenepag (CP-544326)
    CAS: 752187-80-7
    Purity: >99.50%

    Taprenepag (CP-544326) (CP-544326) is a potent and selective prostaglandin EP(2) agonist with IC50s of 10 and 15 nM for human and rat EP2, respectively.

  • GC30299 structure
    GC30299GSK726701A
    CAS: 945721-87-9
    Purity: >98.50%

    GSK726701A is a novel prostaglandin E2 receptor 4 (EP4) partial agonist with a pEC50 of 7.4.

  • GC30307 structure
    GC30307GSK-269984A
    CAS: 892664-04-9
    Purity: >98%

    GSK-269984A is a Prostaglandin E2 Receptor 1 (EP1) antagonist with a pIC50 of 7.9.

  • GC30370 structure
    GC30370Dinoprost (Prostaglandin F2a)
    CAS: 551-11-1
    Purity: >96.50%

    Dinoprost (Prostaglandin F2a) is an orally active, potent prostaglandin receptor (FP receptor) agonist. Dinoprost stimulates myometrial activity, relaxes the cervix, inhibits corpus luteal steroidogenesis, and induces luteolysis by direct action.

  • GC30561 structure
    GC305612-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide
    CAS: 137089-36-2
    Purity: >98%

    2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress.

  • GC30572 structure
    GC30572Aganepag (AGN 210937)
    CAS: 910562-18-4
    Purity: >98%

    Aganepag (AGN 210937) is a potent Prostanoid EP2 receptor agonist, with an EC50 of 0.19 nM, and shows no activity at EP4 receptor.

  • GC30604 structure
    GC30604Darbufelone mesylate (CI-1004 mesylate)
    CAS: 139340-56-0
    Purity: >98.00%

    Darbufelone mesylate (CI-1004 mesylate) (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production.

  • GC30743 structure
    GC30743(+)-Cloprostenol (D-Cloprostenol)
    CAS: 54276-21-0
    Purity: >98.00%

    (+)-Cloprostenol (D-Cloprostenol) is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor.

  • GC31202 structure
    GC31202EP1-antanoist-1
    CAS: 851204-35-8
    Purity: >98%

    EP1-antanoist-1 is a EP1 antagonist with a pKi of 7.54 and an pIC50 of 8.5.

  • GC31445 structure
    GC31445Tiaprost (Iliren)
    CAS: 71116-82-0
    Purity: >98%

    Tiaprost (Iliren) is a prostaglandin F2α (PGF2α) analogue.