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Prostaglandin Receptor

Prostaglandin receptors are a group of g-protein coupled receptor that exhibited a variety of functions in regulation of blood pressure and renal function; smooth muscle contraction; inhibition of plate aggregation; immune response etc.

Products for  Prostaglandin Receptor

  1. Cat.No. Product Name Information
  2. GC16838 (±)-Cloprostenol sodium salt

    (±)16mchlorophenoxy tetranor PGF2α, (±)16mchlorophenoxy tetranor Prostaglandin F2α, DLCloprostenol

    prostaglandin F2α (PGF2α) analog,FP receptor agonist

    (±)-Cloprostenol sodium salt  Chemical Structure
  3. GC30743 (+)-Cloprostenol (D-Cloprostenol)

    DCloprostenol, (+)16mchlorophenoxy tetranor PGF2α, (+)16mchlorophenoxy tetranor Prostaglandin F2α

    (+)-Cloprostenol (D-Cloprostenol) is a prostaglandin F2α (PGF2α) analogue, and shows selective agonistic activity at the prostaglandin receptor. (+)-Cloprostenol (D-Cloprostenol)  Chemical Structure
  4. GC45259 (+)-Cloprostenol (sodium salt)

    DCloprostenol, (+)16mchlorophenoxy tetranor PGF2α, (+)16mchlorophenoxy tetranor Prostaglandin F2α

    (+)-Cloprostenol (sodium salt) is a more water soluble, crystalline form of (+)-cloprostenol. (+)-Cloprostenol (sodium salt)  Chemical Structure
  5. GC12750 (+)-Fluprostenol

    16mtrifluoromethylphenoxy tetranor Prostaglandin F2α

    Prostaglandin F2α (FP) receptor agonist (+)-Fluprostenol  Chemical Structure
  6. GC11133 16,16-Dimethyl Prostaglandin E2

    16,16dimethyl PGE2

    derivative of prostaglandin E2

    16,16-Dimethyl Prostaglandin E2  Chemical Structure
  7. GC30561 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide is a compound that inhibits stress-induced ulcer and low toxicity, and can maintain the content of phospholipase A2 and prostaglandin E2 in ulcerated rats induced by water immersed restrained stress. 2-(E-2-decenoylamino)ethyl 2-(cyclohexylethyl) sulfide  Chemical Structure
  8. GC17719 5-trans U-46619

    5,6-trans U-46619

    Prostaglandin E synthase inhibitor 5-trans U-46619  Chemical Structure
  9. GC10623 ACS 67 analog of latanoprost (free acid),prostaglandin (PG) analog ACS 67  Chemical Structure
  10. GC30572 Aganepag (AGN 210937)

    AGN 210937

    Aganepag (AGN 210937) is a potent Prostanoid EP2 receptor agonist, with an EC50 of 0.19 nM, and shows no activity at EP4 receptor. Aganepag (AGN 210937)  Chemical Structure
  11. GC64435 Aganepag isopropyl


    Aganepag isopropyl (AGN-210961) is an EP2 agonist. Aganepag isopropyl  Chemical Structure
  12. GC31972 AGN 210676 (Simenepag)


    AGN 210676 (Simenepag) is a selective prostaglandin EP2 agonist extracted from patent US20070203222A1, Compound example 23, has an EC50 of 5 nM. AGN 210676 (Simenepag)  Chemical Structure
  13. GC40750 Agnuside Agnuside is an iridoid glycoside originally isolated from V. Agnuside  Chemical Structure
  14. GC17224 AH 23848 (calcium salt) dual antagonist of TP1 and EP4 receptors AH 23848 (calcium salt)  Chemical Structure
  15. GC14879 AH 6809 An EP and DP receptor antagonist AH 6809  Chemical Structure
  16. GC16895 AL 8810

    Antagonist of prostaglandin F2α (FP) receptor.

    AL 8810  Chemical Structure
  17. GC16566 AL 8810 isopropyl ester lipid soluble, esterified prodrug form of AL 8810, a FP receptor antagonist AL 8810 isopropyl ester  Chemical Structure
  18. GC32558 Aligeron Aligeron is a non-selective prostaglandin (PG) antagonist, and has vasodilatory properties. Aligeron  Chemical Structure
  19. GC17347 Alprostadil

    Prostaglandin E1, PGE1;Prostaglandin E1

    Alprostadil (Alprostadil) is a prostanoid receptor ligand, with Kis of 1.1 nM, 2.1 nM, 10 nM, 33 nM and 36 nM for mouse EP3, EP4, EP2, IP and EP1, respectively. Alprostadil  Chemical Structure
  20. GC31718 AM211 (AM211 free acid)

    AM211 free acid

    AM211 (AM211 free acid) is a potent, selective and orally bioavailable prostaglandin D2 (PGD2) receptor type 2 (DP2) antagonist, with IC50s of 4.9 nM, 7.8 nM, 4.9 nM, 10.4 nM for human, mouse, guinea pig, and rat DP2, respectively. AM211 (AM211 free acid)  Chemical Structure
  21. GC50240 AMG 853

    AMG 853

    AMG 853 (AMG 853) is a phenylacetic acid derivative. AMG 853  Chemical Structure
  22. GC31830 AMG-009 AMG-009 is a potent antagonist of prostaglandin D2, with IC50 of 3 nM and 12 nM for CRTH2 and DP receptors, respectively. AMG-009  Chemical Structure
  23. GC31702 Asapiprant (S-555739)


    Asapiprant (S-555739) is a potent and selective DP1 receptor antagonist with a Ki of 0.44 nM. Asapiprant (S-555739)  Chemical Structure
  24. GC31456 AZ-1355

    AZ-1355 is an effctive lipid-lowering compound, which also inhibits platelet aggregation in vivo and elevates the prostaglandin I2/thromboxane A2 ratio in vitro.

    AZ-1355  Chemical Structure
  25. GC60611 AZ12672857 AZ12672857 is an orally active inhibitor of EphB4 (IC50=1.3 nM) and Src kinases. AZ12672857 shows good inhibition of proliferation of c-Src transfected 3T3 cells (IC50=2 nM) as well as autophosphorylation of EphB4 in transfected CHO-K1 cells (IC50=9 nM). AZ12672857  Chemical Structure
  26. GC12434 AZD1981 CRTh2 antagonist,potent and selective AZD1981  Chemical Structure
  27. GC61581 BAY 73-1449 BAY 73-1449 is a selective antagonist of prostacyclin receptor (IP), with high potency (IC50 of less than 0.1 nM) in cAMP assays in Human HEL cells and rat DRG. BAY 73-1449  Chemical Structure
  28. GC15640 BAY u3405


    BAY u3405 is a selective thromboxane A2 (TxA2, IC50=14 nM) antagonist, which also antagonizes CRTH2 (IC50=113 nM) by inhibiting PGD2 binding. BAY u3405  Chemical Structure
  29. GC64958 BAY-1316957 BAY-1316957 is a potent, selective and orally active prostaglandin E2 receptor subtype 4 (EP4-R) antagonist with an IC50 of 15.3 nM for human EP4-R. BAY-1316957  Chemical Structure
  30. GC68738 BAY-6672

    BAY-6672 is an effective and selective antagonist of the human prostaglandin F (FP) receptor, with an IC50 value of 11 nM.

    BAY-6672  Chemical Structure
  31. GC68739 BAY-6672 hydrochloride

    BAY-6672 hydrochloride is an effective and selective antagonist of the human prostaglandin F (FP) receptor, with an IC50 value of 11 nM.

    BAY-6672 hydrochloride  Chemical Structure
  32. GC31872 Benorilate (Benoral) Benorylate (Salipran) is the esterification product of paracetamol and acetylsalicylic acid. Benorilate (Benoral)  Chemical Structure
  33. GC38891 Beraprost sodium Beraprost sodium, a prostacyclin analog, is a stable and orally active prodrug of PGI2. Beraprost sodium  Chemical Structure
  34. GC42927 BGC 20-1531 (hydrochloride)

    PGN 1531

    BGC 20-1531 is a potent and selective antagonist of the prostaglandin E2 receptor subtype 4 (EP4) with Ki values of 11.7, >10,000, and >10,000 nM for EP4, EP2, and EP3, respectively. BGC 20-1531 (hydrochloride)  Chemical Structure
  35. GC62867 BGC-20-1531 free base

    PGN 1531 free base

    BGC-20-1531 (PGN 1531) free base is a potent and selective prostanoid EP4 receptor antagonist, with a pKB of 7.6. BGC-20-1531 free base  Chemical Structure
  36. GC31757 BI-671800


    An antagonist of CRTH2/DP2 BI-671800  Chemical Structure
  37. GC12687 Bimatoprost

    Bimatoprost, 15(S)Bimatoprost, 17phenyl trinor PGF2α ethyl amide

    prostaglandin analog Bimatoprost  Chemical Structure
  38. GC14758 BM 567 dual acting antithrombogenic agent, acting as an inhibitor of thromboxane A2 (TXA2) synthase and as an antagonist of the TP receptor BM 567  Chemical Structure
  39. GC11820 BMY 45778 partial agonist at IP1 prostacyclin receptors BMY 45778  Chemical Structure
  40. GC32002 Bunaprolast (U66858) Bunaprolast (U66858) (U66858) is a potent inhibitor of LTB4 production in human whole blood. Bunaprolast (U66858)  Chemical Structure
  41. GC16539 Butaprost

    15deoxy16Shydroxy17cyclobutyl PGE1 methyl ester, TR 4979

    A selective agonist for the EP2 receptors Butaprost  Chemical Structure
  42. GC14212 BW 245C DP1 receptor agonist BW 245C  Chemical Structure
  43. GC14859 BW 246C

    8-epi BW 245C

    DP receptor agonist BW 246C  Chemical Structure
  44. GC17348 BW A868C prostaglandin D2 antagonist BW A868C  Chemical Structure
  45. GC32487 Carbacyclin (Carbaprostacyclin)

    Carbacyclin, cPGI

    Carbacyclin (Carbaprostacyclin) is a PGI2 analogue, acts as a prostacyclin (PGI2) receptor agonist and vasodilator, and potently inhibits platelet aggregation. Carbacyclin (Carbaprostacyclin)  Chemical Structure
  46. GC50450 Carboprost tromethamine Synthetic Prostaglandin F2α analog Carboprost tromethamine  Chemical Structure
  47. GC18318 CAY10441


    CAY10441 is a potent and selective IP (prostacyclin) receptor antagonist. CAY10441  Chemical Structure
  48. GC35620 CAY10471 Racemate CAY10471 Racemate (TM30089 Racemate) is a potent and highly selective prostaglandin D2 receptor CRTH2 antagonist, with a Ki of 0.6 nM for hCRTH2, selective over human thromboxane A2 receptor TP (Ki, >10000 nM) or PGD2 receptor DP (Ki, 1200 nM). CAY10471 Racemate  Chemical Structure
  49. GC18678 CAY10595 The biological effects of prostaglandin D2 (PGD2) are transduced by at least two 7-transmembrane G protein-coupled receptors, designated DP1 and CRTH2/DP2. CAY10595  Chemical Structure
  50. GC61805 Cefminox sodium Cefminox sodium (MT-141) is a semisynthetic cephamycin, which exhibits a broad spectrum of antibacterial activity. Cefminox sodium  Chemical Structure
  51. GC31981 CGS 15435 CGS 15435, a potent thromboxane (TxA2) synthetase inhibitor with an IC50 of 1 nM, has a selectivity for Tx synthetase 100000-fold greater than that for cyclooxygenase, PGI2 synthetase and lipoxygenase enzymes. CGS 15435  Chemical Structure
  52. GC31994 CI-949 CI-949 is an allergic mediator release inhibitor, which inhibits histamine, leukotriene C4/D4 (LTC4/LTD4), and thromboxane B2 (TXB2) release with IC50s of 11.4 μM, 0.5 μM and 0.1 μM, respectively. CI-949  Chemical Structure
  53. GC10771 CJ-023423


    CJ-023423 (CJ-023423) is a selective EP4 receptor antagonist whose physiological ligand is prostaglandin E2 (PGE2). CJ-023423  Chemical Structure
  54. GC13284 CJ-42794


    EP4 antagonist CJ-42794  Chemical Structure
  55. GC31903 CRTh2 antagonist 1 CRTh2 antagonist 1 is a CRTh2 antagonist with an IC50 of 89 nM. CRTh2 antagonist 1  Chemical Structure
  56. GC31998 CRTH2-IN-1 (Ramatroban analog)

    Ramatroban analog

    CRTH2-IN-1 (Ramatroban analog) (Ramatroban analog) is a selective prostaglandin D2 receptor DP2 (CRTH2) antagonist with an IC50 of 6 nM in a human DP2 binding assay. CRTH2-IN-1 (Ramatroban analog)  Chemical Structure
  57. GC38763 Daltroban

    BM 13505, SKF 96148

    Daltroban (BM-13505) is a selective and specific thromboxane A2 (TXA2) receptor antagonist. Daltroban  Chemical Structure
  58. GC38764 Darbufelone Darbufelone is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone  Chemical Structure
  59. GC30604 Darbufelone mesylate (CI-1004 mesylate) Darbufelone mesylate (CI-1004 mesylate) (CI-1004 mesylate) is a dual inhibitor of cellular PGF2α and LTB4 production. Darbufelone mesylate (CI-1004 mesylate)  Chemical Structure
  60. GC38902 Dazoxiben Dazoxiben is a potent and orally active thromboxane (TX) synthase inhibitor. Dazoxiben  Chemical Structure
  61. GC50393 DG 041 Potent and selective EP3 antagonist; antiplatelet and antithrombotic DG 041  Chemical Structure
  62. GC30370 Dinoprost (Prostaglandin F2a)

    Dinoprost, PGF2α

    Dinoprost (Prostaglandin F2a) (Prostaglandin F2α) is an orally active, potent prostaglandin F (PGF) receptor (FP receptor) agonist. Dinoprost (Prostaglandin F2a)  Chemical Structure
  63. GC10673 E7046


    antagonist of the type 4 prostaglandin E2 (PGE2) receptor EP4 E7046  Chemical Structure
  64. GC31202 EP1-antanoist-1 EP1-antanoist-1 is a EP1 antagonist with a pKi of 7.54 and an pIC50 of 8.5. EP1-antanoist-1  Chemical Structure
  65. GC65317 EP2 receptor antagonist-1 EP2 receptor antagonist-1 (compound 1) is a potent, reversible, and agonist dependent allosteric prostaglandin EP2 receptor antagonist. EP2 receptor antagonist-1  Chemical Structure
  66. GC65987 EP3 antagonist 3 EP3 antagonist 3 (compound 2) is an orally active, potent and selective EP3 antagonist, with a pKi of 8.3. EP3 antagonist 3 shows excellent pharmacokinetic properties. EP3 antagonist 3 can be used for overactive bladder (OAB) research. EP3 antagonist 3  Chemical Structure
  67. GC60152 Epibetulinic acid Epibetulinic acid exhibits potent inhibitory effects on NO and prostaglandin E2 (PGE2) production in mouse macrophages (RAW 264.7) stimulated with bacterial endotoxin with IC50s of 0.7 and 0.6 μM, respectively. Epibetulinic acid  Chemical Structure
  68. GC12101 Epoprostenol

    Epoprostenol, PGI2, Prostacyclin

    Epoprostenol (Prostaglandin I2 (sodium salt)), the synthetic form of the natural prostaglandin derivative prostacyclin (prostaglandin I2), is registered worldwide for the treatment of Pulmonary arterial hypertension (PAH). Epoprostenol  Chemical Structure
  69. GC50722 ER 819762 ER 819762 is an orally active, highly selective prostaglandin E2 (PGE2) EP4 receptor antagonist with an EC50 of 70 nM against human EP4 receptor. ER 819762  Chemical Structure
  70. GC32540 Etersalate (Eterylate) Etersalate (Eterylate) inhibits platelet function and decreases thromboxane A2 (TXA2) levels. Etersalate (Eterylate)  Chemical Structure
  71. GC16170 Ethamsylate Haemostatic drug Ethamsylate  Chemical Structure
  72. GC19147 Evatanepag Evatanepag (CP-533536) is an EP2 receptor selective prostaglandin E2 (PGE2) agonist that induces local bone formation with EC50 of 0.3 nM. Evatanepag  Chemical Structure
  73. GC19153 Fevipiprant

    NVP-QAW039, QAW039

    Fevipiprant(QAW039) is a selective, potent, reversible competitive CRTh2 antagonist with an in vitro dissociation constant KD value of 1.1nM at the CRTh2 receptor and an IC50 value of 0.44 nM for inhibition of PGD2-induced eosinophil shape change in human whole blood. Fevipiprant  Chemical Structure
  74. GC38379 Furprofen Furprofen is an non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. Furprofen  Chemical Structure
  75. GN10069 Ginsenoside Ro

    Chikusetsusaponin V

    Ginsenoside Ro  Chemical Structure
  76. GC30307 GSK-269984A GSK-269984A is a Prostaglandin E2 Receptor 1 (EP1) antagonist with a pIC50 of 7.9. GSK-269984A  Chemical Structure
  77. GC30299 GSK726701A GSK726701A is a novel prostaglandin E2 receptor 4 (EP4) partial agonist with a pEC50 of 7.4. GSK726701A  Chemical Structure
  78. GC14812 GW 627368 prostanoid EP4 receptor antagonist GW 627368  Chemical Structure
  79. GC69224 HHS-0701

    HHS-0701 is a sulfur-triazole exchange (SuTEx) ligand and an effective inhibitor of the tyrosine-reactive prostaglandin reductase 2 (PTGR2). HHS-0701 blocks the metabolism of lipid substrate 15-Keto-PGE2 by PTGR2.

    HHS-0701  Chemical Structure
  80. GC68349 Ifetroban sodium

    BMS-180291 sodium

    Ifetroban sodium  Chemical Structure
  81. GC15911 Iloprost


    Prostacyclin (PGI2) analog;IP, EP1 and EP3 receptors agonist Iloprost  Chemical Structure
  82. GC36379 KAG-308 KAG-308 is a potent selective and orally active agonist of EP4 receptor (a prostaglandin E2 receptor subtype), suppresses colitis and promotes histological mucosal healing, potently inhibits TNF-α production. KAG-308  Chemical Structure
  83. GC32653 KF 13218 KF 13218 is a potent, selective and long lasting thromboxane B2 (TXB2) synthase inhibitor with an IC50 value of 5.3±1.3 nM. KF 13218  Chemical Structure
  84. GC31983 KP496 KP496 is a selective, dual antagonist for Leukotriene D4 receptor and Thromboxane A2 receptor. KP496  Chemical Structure
  85. GC62667 KW-8232 KW-8232, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2. KW-8232  Chemical Structure
  86. GC31633 KW-8232 free base KW-8232 free base, an orally active anti-osteoporotic agent, and can reduces the biosynthesis of PGE2. KW-8232 free base  Chemical Structure
  87. GC31768 L 888607 L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607  Chemical Structure
  88. GC31975 L 888607 Racemate L 888607 Racemate is a selective prostaglandin D2 receptor subtype 1 (DP1) antagonist, with Kis of 132 nM and 17 nM for DP1 and thromboxane A2 receptor (TP), respectively. L 888607 Racemate  Chemical Structure
  89. GC14173 L-161,982 EP4 receptor antagonist L-161,982  Chemical Structure
  90. GC13067 L-655,240 thromboxane A2/prostaglandin endoperoxide receptor antagonist L-655,240  Chemical Structure
  91. GC13609 L-670,596 thromboxane A2/prostaglandin endoperoxide receptor antagonist L-670,596  Chemical Structure
  92. GC10304 L-798,106

    CM 9, GW 671021

    prostanoid EP3 receptor antagonist L-798,106  Chemical Structure
  93. GC44021 L-826,266 L-826,266 is a potent and selective competitive antagonist of the prostaglandin E2 receptor subtype EP3 (Ki = 0.8 nM). L-826,266  Chemical Structure
  94. GC39632 Laflunimus Laflunimus (HR325) is an immunosuppressive agent and an analogue of the Leflunomide-active metabolite A77 1726. Laflunimus  Chemical Structure
  95. GC11833 Laropiprant

    Cardaptive; MK 0524; MK-0524,Laropiprant

    A potent, selective DP1 receptor antagonist Laropiprant  Chemical Structure
  96. GC14004 Latanoprost

    CAY530500, 17phenyl13,14dihydro trinor PGF2α isopropyl ester, 17phenyl13,14dihydro trinor Prostaglandin F2α isopropyl ester

    FP prostaglandin receptor agonist

    Latanoprost  Chemical Structure
  97. GC41229 Latanoprost (free acid)

    LatFA, 17phenyl13,14dihydro trinor Prostaglandin F2α, PhXA85

    Latanoprost (free acid), an analog of prostaglandin (PG) F2α, is an selective prostanoid receptor (FP) agonist that specifically activates the FP-PG receptor. Latanoprost (free acid)  Chemical Structure
  98. GC40854 Latanoprost Lactone Diol Latanoprost is an F-series prostaglandin analog which has been approved for use as an ocular hypotensive drug. Latanoprost Lactone Diol  Chemical Structure
  99. GC33550 LCB-2853 LCB-2853 is an antagonist of thromboxane A2 (TXA2) receptor, with antiplatelet and antithrombotic activities. LCB-2853  Chemical Structure
  100. GC60225 Licarin A Licarin A ((+)-Licarin A), a neolignan, significantly and dose-dependently reduces TNF-α production (IC50=12.6 μM) in dinitrophenyl-human serum albumin (DNP-HSA)-stimulated RBL-2H3 cells. Licarin A  Chemical Structure
  101. GC62493 MF-766 MF-766 is a highly potent, selective and orally active EP4 antagonist with a Ki of 0.23 nM. MF-766  Chemical Structure

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