Sigma Receptor
Sigma receptors are non-opioid receptors that interacted with psychostimulants such as cocaine and methamphetamine. It is associated with central nervous systems diseases, cancer and neuropathic pain etc.
Products Related to Sigma Receptor(59)
- GC62960EST73502 hydrochlorideCAS: 2535970-65-9Purity: >98.00%
EST73502 hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with Kis of 64 nM and 118 nM for MOR and σ1R, respectively.
- GC65178KB-5492 free baseCAS: 113594-64-2Purity: >99.00%
KB-5492 free base is a potent and selective inhibitor of sigma receptor, inhibits specific [3H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC50 of 3.15 μM.
- GC71102S1R agonist 1 hydrochlorideCAS: 242487-82-7Purity: >99.00%
S1R agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively.
- GC71103S1R agonist 2CAS: 150085-21-5Purity: >98.00%
S1R agonist 2 (Compound 8b) is a selective S1R agonist with Kis of 1.1 nM and 88 nM for S1R and S2R, respectively.
- GC71104S1R agonist 2 hydrochloridePurity: >98.00%
S1R agonist 2 (Compound 8b) hydrochloride is a selective S1R agonist with Kis of 1.1 nM and 88 nM for S1R and S2R, respectively.
- GC71107AB21 hydrochlorideCAS: 3026677-24-4Purity: >99.00%
AB21 hydrochloride is a potent and selective S1R antagonist with Kis of 13, 102 nM for S1R and S2R.
- GC73273S1R agonist 1CAS: 193354-70-0Purity: >98.00%
S1R agonist 1 (Compound 6b) is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively.
- GC79779N-Desmethyl xanomelineCAS: 131986-96-4Purity: >98%
N-Desmethyl xanomeline is a pharmacologically active metabolite of Xanomeline.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC62960 | EST73502 hydrochloride | 2535970-65-9 | >98.00% | |
EST73502 hydrochloride is a selective, orally active and blood-brain barrier (BBB) penetrant dual μ-opioid receptor (MOR) agonist and σ1 receptor (σ1R) antagonist, with Kis of 64 nM and 118 nM for MOR and σ1R, respectively. | ||||
| GC63801 | CM398 | 1121931-70-1 | >98.00% | |
CM398 is a highly selective, orally active sigma-2 receptor ligand (Ki=0.43 nM), with high sigma-1/sigma-2 selectivity rato (1000-fold). | ||||
| GC65178 | KB-5492 free base | 113594-64-2 | >99.00% | |
KB-5492 free base is a potent and selective inhibitor of sigma receptor, inhibits specific [3H]1,3-di(2-tolyl)guanidine (DTG) binding to the sigma receptor with an IC50 of 3.15 μM. | ||||
| GC65450 | CT1812 | 1802632-22-9 | >97.00% | |
CT1812 (Sigma-2 receptor antagonist 1) is a sigma-2 (σ-2) receptor antagonist. | ||||
| GC67893 | Sigma-LIGAND-1 hydrochloride | 139652-86-1 | >98% | |
| GC71102 | S1R agonist 1 hydrochloride | 242487-82-7 | >99.00% | |
S1R agonist 1 (Compound 6b) hydrochloride is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively. | ||||
| GC71103 | S1R agonist 2 | 150085-21-5 | >98.00% | |
S1R agonist 2 (Compound 8b) is a selective S1R agonist with Kis of 1.1 nM and 88 nM for S1R and S2R, respectively. | ||||
| GC71104 | S1R agonist 2 hydrochloride | - | >98.00% | |
S1R agonist 2 (Compound 8b) hydrochloride is a selective S1R agonist with Kis of 1.1 nM and 88 nM for S1R and S2R, respectively. | ||||
| GC71107 | AB21 hydrochloride | 3026677-24-4 | >99.00% | |
AB21 hydrochloride is a potent and selective S1R antagonist with Kis of 13, 102 nM for S1R and S2R. | ||||
| GC73273 | S1R agonist 1 | 193354-70-0 | >98.00% | |
S1R agonist 1 (Compound 6b) is a selective S1R agonist with Kis of 0.93 nM and 72 nM for S1R and S2R, respectively. | ||||
| GC79779 | N-Desmethyl xanomeline | 131986-96-4 | >98% | |
N-Desmethyl xanomeline is a pharmacologically active metabolite of Xanomeline. | ||||