mTOR

Desmethyl-VS-5584 hydrochloride is a dimethyl analog of VS-5584, a potent and selective dual mTOR/PI3K inhibitor, with a pyridine[2,3-d]pyrimidine structure.

HTH-01-091 TFA is a potent and selective maternal embryonic leucine zipper kinase (MELK) inhibitor, with an IC50 of 10.5 nM.

NEO214 is an autophagy inhibitor and a covalent conjugate of the PDE4 inhibitor Rolipram and perillyl alcohol.

ALK-IN-26 is an ALK inhibitor with IC50 value of 7.0 μM for ALK tyrosine kinase.

RMC-4998 is an orally active inhibitor targeting the active or GTP-bound state of the KRASG12C mutant.

IBL-302 (AMU302) is an orally available dual-signaling inhibitor of PIM and PI3K/AKT/mTOR with activity against breast cancer and neuroblastoma.

SKI-349 is a dual-targeted inhibitor of sphingosine kinase 1/2 (SPHK1/2) and microtubule assembly (MDA).

KTC1101 is an orally active pan-PI3K inhibitor.

ASCT2-IN-1 (compound 20k) is an ASCT2 inhibitor with IC50 values of 5.6 μM and 3.5 μM in cells A549 and HEK293, respectively.

ASCT2-IN-2 (compound 25e) is an ASCT2 inhibitor with IC50 of 5.14 μM.

WRX606 is an inhibitor for mTOR complex 1 (mTORC1).

HBS-101 is a selectively, orally active, brain-penetrant, Midkine (MDK) inhibitor ( K D = 38.4 nM).

T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor.

RMC-4998 TFA is an orally active inhibitor targeting the active or GTP-bound state of the KRAS G12C mutant.

Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide ( GIP ) and glucagon-like peptide-1 ( GLP-1 ) receptor agonist.

Anti-CD160 Antibody (MAT 302) (CL1-R2) is a human monoclonal antibody targeting CD160.

Anti-IL11 Antibody (X203, Mouse IgG ) is an antibody targeting IL-11.

Cryptolepine is an orally active multi-potent alkaloid with anti-cancer, anti-bacterial, anti-viral, anti-malarial, anti-inflammatory, anti-hyperglycemic, relieve pain and other properties.

Gedatolisib -d 8 (PKI-587-d 8 ) is the deuterium labeled Gedatolisib.

Calebin A is a PI3K/Akt/mTOR, MAPK, and NF-κB inhibitor with oral effectiveness.

GP262 is a PI3K/mTOR PROTAC degrader targeting PI3Kγ, PI3Kα and mTOR with DC 50 values of 42.23 nM, 227.4 nM and 45.4 nM, respectively in MDA-MB-231 cells.

PI3K/mTOR ligand-1 is a ligand for the target protein of PROTAC ( PI3K / mTOR ).

FGF7p is a small molecule peptide and a potential bladder protector.

Sialorphin TFA is a neutral endopeptidase ( NEP ) and aminopeptidase N ( APN ) inhibitor that responds to androgen signals.