PI3K/Akt/mTOR Signaling

Cat.No. Product Name Information

GC10350 TIC10 isomer

Potent Akt/ERK inhibitor

GC17330 (+)-Usniacin Naturally occurring dibenzofuran derivative (+)-Usniacin Chemical Structure

GC63524 (32-Carbonyl)-RMC-5552 (32-Carbonyl)-RMC-5552 Chemical Structure

GC62122 (E)-Akt inhibitor-IV (E)-Akt inhibitor-IV Chemical Structure

GC62736 (E/Z)-GSK-3β inhibitor 1 (E/Z)-GSK-3β inhibitor 1 Chemical Structure

GC63802 (R)-PS210 (R)-PS210 Chemical Structure

GC62450 (S)-PI3Kα-IN-4 (S)-PI3Kα-IN-4 Chemical Structure

GC35037 1,3-Dicaffeoylquinic acid 1,3-Dicaffeoylquinic acid Chemical Structure

GC13907 1-Azakenpaullone GSK-3β inhibitor,potent and selective,cell-permeable 1-Azakenpaullone Chemical Structure

GC41992 1-Deoxynojirimycin (hydrochloride) 1-Deoxynojirimycin (1-dNM) (hydrochloride), produced by Bacillus species, is a glucose analog that potently inhibits α-glucosidase I and II.

1-Deoxynojirimycin (hydrochloride) Chemical Structure

GC42018 1-O-Octadecyl-2-O-methyl-sn-glycerol 1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA).

1-O-Octadecyl-2-O-methyl-sn-glycerol Chemical Structure

GC13006 10-DEBC hydrochloride Akt inhibitor 10-DEBC hydrochloride Chemical Structure

GC41979 17β-hydroxy Wortmannin 17β-hydroxy Wortmannin is an analog of wortmannin. 17β-hydroxy Wortmannin Chemical Structure

GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone 2,3-Dimethoxy-5-methyl-p-benzoquinone, also known as coenzyme Q0, is a key intermediate in the synthesis of coenzyme Q, coenzyme Q10, other ubiquinones, and vitamin E.

2,3-Dimethoxy-5-methyl-p-benzoquinone Chemical Structure

GC42237 3,5-dimethyl PIT-1 PtdIns-(3,4,5)-P3 (PIP3) serves as an anchor for the binding of signal transduction proteins bearing pleckstrin homology (PH) domains such as phosphatidylinositol 3-kinase (PI3K) or PTEN. 3,5-dimethyl PIT-1 Chemical Structure

GC13992 3-Guanidinopropionic Acid AMPK stimulator 3-Guanidinopropionic Acid Chemical Structure

GC10710 3-Methyladenine Class III PI3K inhibitor 3-Methyladenine Chemical Structure

GC32767 3BDO 3BDO Chemical Structure

GC12078 3CAI AKT inhibitor 3CAI Chemical Structure

GC14306 3F8 GSK-3β inhibitor 3F8 Chemical Structure

GC16960 4,5,6,7-Tetrabromobenzimidazole CK2 inhibitor

4,5,6,7-Tetrabromobenzimidazole Chemical Structure

GN10093 6-gingerol Extracted from Zingiber officinale Roscoe;Suitability:Methanol,ethanol,DMSO;Store the product in sealed,cool and dry condition 6-gingerol Chemical Structure

GC31348 7-Methoxyisoflavone 7-Methoxyisoflavone Chemical Structure

GC16157 740 Y-P PI 3-kinase activator,cell permeable 740 Y-P Chemical Structure

GC39152 9-ING-41 9-ING-41 Chemical Structure

GC10336 A 1070722 GSK-3 inhibitor A 1070722 Chemical Structure

GC12502 A-443654 Akt inhibitor,potent and selective A-443654 Chemical Structure

GC11875 A-674563

Akt1/PKA/CDK2 inhibitor,potent and selective

GC35212 A-674563 hydrochloride A-674563 hydrochloride Chemical Structure

GC11234 A-769662 AMPK activator,potent and reversible A-769662 Chemical Structure

GC17550 A66 P110α inhibitor A66 Chemical Structure

GC10860 Acalisib (GS-9820) PI3Kδ inhibitor Acalisib (GS-9820) Chemical Structure

GC35242 Actein Actein Chemical Structure

GC16475 Afuresertib pan-AKT inhibitor Afuresertib Chemical Structure

GC42747 Afuresertib (hydrochloride) Afuresertib is a selective, orally bioavailable inhibitor of Akt1, 2, and 3 with Ki values of 0.08, 2, and 2.6 nM, respectively. Afuresertib (hydrochloride) Chemical Structure

Afuresertib (hydrochloride) Chemical Structure

GC10518 AICAR AMPK activator AICAR Chemical Structure

GC10580 AICAR phosphate AMPK activator AICAR phosphate Chemical Structure

GC42759 Akt Inhibitor IV Akt inhibitor IV is an inhibitor of Akt activation that inhibits Akt-mediated nuclear export of Forkhead box class O transcription factor 1a (FOXO1a; IC50 = 625 nM) and reduces phosphorylation of Akt at Ser473 and Thr308 in a dose-dependent manner. Akt Inhibitor IV Chemical Structure

GC11589 AKT inhibitor VIII Allosteric Akt kinase inhibitor AKT inhibitor VIII Chemical Structure

GC16366 AKT Kinase Inhibitor AKT Kinase Inhibitor AKT Kinase Inhibitor Chemical Structure

GC33308 AKT-IN-1 AKT-IN-1 Chemical Structure

GC62190 AKT-IN-6 AKT-IN-6 Chemical Structure

GC32939 Akt1 and Akt2-IN-1 Akt1 and Akt2-IN-1 Chemical Structure

GC15841 Alsterpaullone CDKs and GSK3β inhibitor Alsterpaullone Chemical Structure

GC42776 Amarogentin

A secoiridoid glycoside with diverse biological activities

GC13913 AMG319 PI3Kδ inhibitor AMG319 Chemical Structure

GC11190 AMPK activator AMPK activator AMPK activator Chemical Structure

GC35327 AMPK activator 1 AMPK activator 1 Chemical Structure

GC62841 AMPK activator 4 AMPK activator 4 Chemical Structure

GC16534 Ampkinone AMPK activator Ampkinone Chemical Structure

GC18374 API-1 API-1 is an inhibitor of Akt that reduces the level of phosphorylated Akt (IC50 = ~0.8 uM in OVCAR3 cells) by binding to Akt and blocking its translocation to the cell membrane. API-1 Chemical Structure

GC31661 APY0201 APY0201 Chemical Structure

GC15425 AR-A014418 GSK3β inhibitor, ATP-competitive and selective AR-A014418 Chemical Structure

GC19036 ARQ-092 ARQ-092 is an orally bioavailable, selective, and potent allosteric Akt inhibitor with IC50s of 2.7 nM, 14 nM and 8.1 nM for Akt1, Akt2, Akt3, respectively. ARQ-092 Chemical Structure

GN10647 Artemisinine Extracted from Artemisia annua L.;Suitability:Acetone,benzene,chloroform,ethyl acetate and acetic acid;Store the product in sealed,cool and dry condition Artemisinine Chemical Structure