Drug Metabolite
Drug metabolite results when a drug is metabolized into a modified form which continues to produce effects. Drug metabolism redox reactions such as heteroatom dealkylations, hydroxylations, heteroatom oxygenations, reductions, and dehydrogenations can yield active metabolites, and in rare cases even conjugation reactions can yield an active metabolite.
Products Related to Drug Metabolite(546)
- GC49875(±)-N-desmethyl Venlafaxine (hydrochloride)CAS: 93413-90-2Purity: >95.00%
A minor active metabolite of venlafaxine
- GC52019Norpropranolol (hydrochloride)CAS: 62618-09-1Purity: >98.00%
An active metabolite of propranolol
- GC52045N-desmethyl AzelastineCAS: 47491-38-3Purity: >98.00%
N-desmethyl Azelastine is a main active metabolite of Azelastine that is oxidatively metabolized by the cytochrome P450 enzyme system with a protein binding rate of 97% and an elimination half-life of 54 hours.
- GC52054Ranitidine S-oxideCAS: 73851-70-4Purity: >90.00%
Ranitidine S-oxide is the metabolite of Ranitidine.
- GC52060Trimipramine N-oxideCAS: 14171-70-1Purity: >90.00%
Trimipramine N-oxide is an active metabolite of the tricyclic antidepressant trimipramine.
- GC52074Loratadine N-oxideCAS: 165739-62-8Purity: >95.00%
Loratadine n-oxide is a metabolite of Loratadine.
- GC52076Temozolomide AcidCAS: 113942-30-6Purity: >98.00%
Temozolomide Acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide Acid has an activity similar to the parent compound Temozolomide with the same anticancer activity.
- GC522275-(3',4'-Dihydroxyphenyl)-γ-ValerolactoneCAS: 21618-92-8Purity: >95.00%
An active metabolite of various polyphenols
- GC523243-(3-Hydroxyphenyl)propionic Acid sulfateCAS: 86321-32-6Purity: >95.00%
A metabolite of certain phenols and glycosides
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49875 | (±)-N-desmethyl Venlafaxine (hydrochloride) | 93413-90-2 | >95.00% | |
A minor active metabolite of venlafaxine | ||||
| GC52005 | Triazolomethylindole-3-acetic Acid | 177270-91-6 | >95.00% | |
A metabolite of rizatriptan | ||||
| GC52007 | N-hydroxylamine Dapsone | 32695-27-5 | >98.00% | |
An active metabolite of dapsone | ||||
| GC52019 | Norpropranolol (hydrochloride) | 62618-09-1 | >98.00% | |
An active metabolite of propranolol | ||||
| GC52024 | Aripiprazole N-oxide | 573691-09-5 | >90.00% | |
A metabolite of aripiprazole | ||||
| GC52029 | 2-Aminoflubendazole | 82050-13-3 | >95.00% | |
| GC52033 | S-Methyl-D-penicillamine | 29913-84-6 | >95.00% | |
A metabolite of D-penicillamine | ||||
| GC52035 | Esmolol Acid (hydrochloride) | 83356-60-9 | >98.00% | |
An active metabolite of esmolol | ||||
| GC52045 | N-desmethyl Azelastine | 47491-38-3 | >98.00% | |
N-desmethyl Azelastine is a main active metabolite of Azelastine that is oxidatively metabolized by the cytochrome P450 enzyme system with a protein binding rate of 97% and an elimination half-life of 54 hours. | ||||
| GC52052 | Dofetilide N-oxide | 144449-71-8 | >98.00% | |
| GC52054 | Ranitidine S-oxide | 73851-70-4 | >90.00% | |
Ranitidine S-oxide is the metabolite of Ranitidine. | ||||
| GC52059 | AMOZ | 43056-63-9 | >98.00% | |
| GC52060 | Trimipramine N-oxide | 14171-70-1 | >90.00% | |
Trimipramine N-oxide is an active metabolite of the tricyclic antidepressant trimipramine. | ||||
| GC52074 | Loratadine N-oxide | 165739-62-8 | >95.00% | |
Loratadine n-oxide is a metabolite of Loratadine. | ||||
| GC52076 | Temozolomide Acid | 113942-30-6 | >98.00% | |
Temozolomide Acid is a carboxylic acid derivative of Temozolomide. Temozolomide is a DNA alkylating agent, methylating the guanine and adenine bases of DNA, causing breaks in DNA double strand, cell cycle arrest, and eventually cell death. Temozolomide Acid has an activity similar to the parent compound Temozolomide with the same anticancer activity. | ||||
| GC52132 | N-desmethyl Diltiazem (hydrochloride) | 130606-60-9 | >90.00% | |
| GC52168 | Aripiprazole N,N-dioxide | 573691-13-1 | >90.00% | |
| GC52173 | N-desmethyl-Doxylamine (succinate) | 2731375-61-2 | >90.00% | |
| GC52177 | Perphenazine Sulfoxide | 10078-25-8 | >98.00% | |
| GC52227 | 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone | 21618-92-8 | >95.00% | |
An active metabolite of various polyphenols | ||||
| GC52324 | 3-(3-Hydroxyphenyl)propionic Acid sulfate | 86321-32-6 | >95.00% | |
A metabolite of certain phenols and glycosides | ||||
| GC52368 | DL-Sulforaphane Glutathione | 289711-21-3 | >98.00% | |
A metabolite of sulforaphane | ||||
| GC52478 | Telmisartan Acyl-β-D-Glucuronide (hydrate) | - | >95.00% | |
A major metabolite of telmisartan | ||||
| GC60124 | DCBA | 72236-23-8 | >99.50% | |
DCBA is a metabolite of insect repellent N-N-diethyl-meta-toluamide (DEET). | ||||