Thrombin

Napsagatran hydrate (Ro 46-6240 hydrate) is a novel and specific thrombin inhibitor.

TP508 is a 23-amino acid nonproteolytic thrombin peptide that represents a portion of the receptor-binding domain of thrombin molecule.

Argatroban (monohydrate) (MD-805 (monohydrate)) is a direct, selective thrombin inhibitor.

Bivalirudin TFA is a synthetic 20 residue peptide which reversibly inhibits thrombin.

Dabigatran ethyl ester hydrochloride is a potent inhibitor of ribosyldihydronicotinamide dehydrogenase (NQO2) with an IC50 value of 0.8 μM and a thrombin inhibitor.

Odiparcil (SB-424323) is an orally active beta-d-thioxyloside analog with antithrombotic activity associated with a reduced risk of adverse bleeding events.

A prodrug of melagatran, a thrombin inhibitor

TP508 TFA is a 23-amino acid nonproteolytic thrombin peptide that represents a portion of the receptor-binding domain of thrombin molecule.

PPACK is a potent selective and irreversible thrombin inhibitor that inhibits human alpha thrombin with a K i value of 0.24 nM.

Melagatran is a direct and orally active inhibitor of thrombin, without interacting with any other enzymes in the coagulation cascade or fibrinolytic enzymes aside from thrombin.

Thrombin (MW 37kDa) is a Na + -activated, allosteric serine protease.

Edoxaban impurity 4 is an impurity of Edoxaban.

Dabigatran-d4 is deuterium labeled Dabigatran.

NP-313 is a potent antithrombotic agent that inhibits platelet aggregation and activation.

Sulodexide is an orally active mixture of glycosaminoglycans composed of low molecular weight heparin (80%) and dermatan sulfate (20%).

FXIIa-IN-4 (compound 22) is a potent, selective human FXIIa inhibitor with the IC50 of 0.032 μM, 0.30 μM, ＞50 μM for FXIIa, thrombin and FXIa, respectively.

Rovunaptabin sodium (ARC 183 sodium) is a DNA aptamer, which is a single-stranded DNA molecule consisting of 15 deoxynucleotides that forms well-defined three-dimensional configuration, allowing it to bind to thrombin with high affinity and specificity.