Rho
Rho GTPases act as molecular switches that convert and amplify external signals into cellular effects upon activation of cell surface receptor in various signaling transduction pathway. It functions in cell proliferation, motility, survival cytoskeletal remodeling and membrane trafficking etc.
Products Related to Rho(13)
- GC10069NSC 23766 trihydrochlorideCAS: 1177865-17-6Purity: >99.00%
NSC 23766 trihydrochloride is a selective Rac1 GTPase inhibitor that suppresses Rac1 activation by specifically blocking the guanine nucleotide exchange factors Trio and Tiam1, with an IC₅₀ of approximately 50μM for Rac1.
- GC12817K-115 hydrochloride dihydrateCAS: 887375-67-9Purity: >99.50%
K-115 hydrochloride dihydrate (K-115) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively.
- GC14701Zoledronic AcidCAS: 118072-93-8Purity: >99.00%
Zoledronic Acid is a third-generation nitrogen-containing bisphosphonate bone resorption inhibitor.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC10030 | EHop-016 | 1380432-32-5 | >99.00% | |
EHop-016 is a potent inhibitor of Rac GTPase Rac1, with an IC 50 value of 1.1μM. | ||||
| GC10069 | NSC 23766 trihydrochloride | 1177865-17-6 | >99.00% | |
NSC 23766 trihydrochloride is a selective Rac1 GTPase inhibitor that suppresses Rac1 activation by specifically blocking the guanine nucleotide exchange factors Trio and Tiam1, with an IC₅₀ of approximately 50μM for Rac1. | ||||
| GC12470 | ZCL278 | 587841-73-4 | >98.00% | |
Selective Cdc42 inhibitor | ||||
| GC10419 | (R)-CCG-1423 | 2309931-09-5 | >98% | |
Rho inhibitor | ||||
| GC11754 | AS 1892802 | 928320-12-1 | >98% | |
ROCK inhibitor,potent and ATP-competitive | ||||
| GC12795 | CCG-1423 | 285986-88-1 | >99.50% | |
RhoA inhibitor | ||||
| GC12817 | K-115 hydrochloride dihydrate | 887375-67-9 | >99.50% | |
K-115 hydrochloride dihydrate (K-115) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively. | ||||
| GC14497 | (S)-CCG-1423 | 2319939-24-5 | >98% | |
Rho inhibitor | ||||
| GC14986 | CCG-100602 | 1207113-88-9 | >99.50% | |
Rho pathway inhibitor | ||||
| GC15170 | SB 772077B dihydrochloride | 607373-46-6 | >98.50% | |
Rho-kinase (ROCK) inhibitor | ||||
| GC15478 | 6H05 | 1469338-01-9 | >98% | |
K-Ras inhibitor | ||||
| GC14701 | Zoledronic Acid | 118072-93-8 | >99.00% | |
Zoledronic Acid is a third-generation nitrogen-containing bisphosphonate bone resorption inhibitor. | ||||
| GC17388 | K-Ras(G12C) inhibitor 6 | 2060530-16-5 | >98% | |
K-Ras (G12C) inhibitor | ||||