Crolibulin (Synonyms: EPC2407) |
| Catalog No.GC19112 |
La crolibulina (EPC2407) es un inhibidor de la polimerizaciÓn de la tubulina, con una potente inducciÓn de la apoptosis e inhibiciÓn del crecimiento celular. La crolibulina tiene actividad antitumoral. La crolibulina también tiene toxicidad cardiovascular y neurotoxicidad.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1000852-17-4
Sample solution is provided at 25 µL, 10mM.
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Crolibulin is a small molecule tubulin polymerization inhibitor.
References:
[1]. Kalmuk J, et al. Multimodal imaging guided preclinical trials of vascular targeting in prostate cancer. Oncotarget. 2015 Sep 15;6(27):24376-92.
[2]. Zhai X, et al. Discovery and Optimization of Novel 5-Indolyl-7-arylimidazo[1,2-a]pyridine-8-carbonitrile Derivatives as Potent Antitubulin Agents Targeting Colchicine-binding Site. Sci Rep. 2017 Feb 27;7:43398.
Average Rating: 5 (Based on Reviews and 34 reference(s) in Google Scholar.)
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