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Inicio >> Signaling Pathways >> Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.

Targets for  Cell Cycle/Checkpoint

Products for  Cell Cycle/Checkpoint

  1. Cat.No. Nombre del producto Información
  2. GC40702 α-D-Galactopyranosylphenyl isothiocyanate

    α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.

     α-D-Galactopyranosylphenyl isothiocyanate Chemical Structure
  3. GC45226 β-BHC

    β-HCH, β-Hexachlorocyclohexane, β-Lindane

     β-BHC is an isomer of the organochlorine pesticide γ-lindane that is a potential impurity found in commercial preparations of lindane. β-BHC Chemical Structure
  4. GC41676 (±)-Nornicotine

    DL-Nornicotine, (R,S)-Nornicotine

     (±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. (±)-Nornicotine Chemical Structure
  5. GC49482 (±)-Nornicotine-d4

    DL-Nornicotine-d4, (R,S)-Nornicotine-d4

     An internal standard for the quantification of (±)-nornicotine (±)-Nornicotine-d4 Chemical Structure
  6. GC46308 (±)-Sitagliptin-d4 (hydrochloride) A neuropeptide with diverse biological activities (±)-Sitagliptin-d4 (hydrochloride) Chemical Structure
  7. GC41684 (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane

    BMC, Vectrase P

     (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups. (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane Chemical Structure
  8. GC40802 (±)12(13)-DiHOME

    Isoleukotoxin diol

    (±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

     (±)12(13)-DiHOME Chemical Structure
  9. GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol

    (±)214,15EG

     2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol Chemical Structure
  10. GC45890 (+)-Abscisic Acid-d6

    (S)​-​(+)​-​Abscisic acid-d6; ABA-d6

     (+)-Ácido abscísico-d6 (ABA-d6) es ácido abscísico marcado con deuterio. (+)-Abscisic Acid-d6 Chemical Structure
  11. GC70332 (+)-Erinacin A (+)-Erinacin A es un compuesto contra el cáncer que se puede aislar del hongo Hericium erinaceum. (+)-Erinacin A Chemical Structure
  12. GC62728 (1E)-CFI-400437 dihydrochloride El diclorhidrato de (1E)-CFI-400437 es un potente inhibidor de PLK4 (IC50= 0,6 nM) y selectivo frente a otros miembros de la familia PLK (>10 μM). El diclorhidrato de (1E)-CFI-400437 inhibe Aurora A, Aurora B, KDR y FLT-3 con IC50 de 0,37, 0,21, 0,48 y 0,18 μM, respectivamente. Actividad antiproliferativa. (1E)-CFI-400437 dihydrochloride Chemical Structure
  13. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt) Chemical Structure
  14. GC41698 (D)2-Rh 110 (trifluoroacetate salt)

    D2R, (Asp)2-Rhodamine 110, Rhodamine 110 bis-(L-aspartic acid amide)

     (D)2-Rh 110 is a fluorogenic caspase substrate. (D)2-Rh 110 (trifluoroacetate salt) Chemical Structure
  15. GC41268 (E)-2-Hexadecenal

    trans-2-Hexadecenal

     Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase. (E)-2-Hexadecenal Chemical Structure
  16. GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe. (E)-2-Hexadecenal Alkyne Chemical Structure
  17. GC46335 (E)-Fenpyroximate

    Fenpyroximate, NNI-850

     El (E)-fenpiroximato es un potente acaricida. (E)-Fenpyroximate Chemical Structure
  18. GC10419 (R)-CCG-1423 Rho inhibitor (R)-CCG-1423 Chemical Structure
  19. GC16429 (R)-DRF053 dihydrochloride cdk/CK1 inhibitor,potent and ATP-competitive (R)-DRF053 dihydrochloride Chemical Structure
  20. GC41719 (R)-nitro-Blebbistatin

    R(-)7Desmethyl8nitro Blebbistatin

     (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin. (R)-nitro-Blebbistatin Chemical Structure
  21. GC46347 (S)-(+)-Methoprene

    Altosid, d-Methoprene, ZR 2458

     El (S)-metopreno es un análogo de la hormona juvenil que impide que el insecto cambie de pupa a adulto y se usa como insecticida. (S)-(+)-Methoprene Chemical Structure
  22. GC41557 (S)-3'-amino Blebbistatin

    (-)-3'-amino Blebbistatin, m-amino Blebbistatin, meta-amino Blebbistatin

     (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-amino Blebbistatin Chemical Structure
  23. GC41484 (S)-3'-hydroxy Blebbistatin

    (-)-3'-hydroxy Blebbistatin, meta-hydroxy-Blebbistatin, m-hydroxy-Blebbistatin

     (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-hydroxy Blebbistatin Chemical Structure
  24. GC52192 (S)-4'-nitro-Blebbistatin

    (-)-4'-nitro-Blebbistatin, p-nitro-Blebbistatin, para-nitro-Blebbistatin

     (S)-4'-nitro-Blebbistatin es un inhibidor de miosina II no citotÓxico, fotoestable, fluorescente y especÍfico, utilizado en el estudio del papel especÍfico de la miosina II en estudios fisiolÓgicos, de desarrollo y biolÓgicos celulares. (S)-4'-nitro-Blebbistatin Chemical Structure
  25. GC14497 (S)-CCG-1423 Rho inhibitor (S)-CCG-1423 Chemical Structure
  26. GC34999 (S)-Ceralasertib

    (S)-AZD6738

     (S)-Ceralasertib ((S)-AZD6738) se extrae de la patente WO2011154737A1, Compuesto II, presenta una IC50 de 2,578 nM.(S)-Ceralasertib es un potente y selectivo inhibidor de ATR de sulfoximina morfolinopirimidina con excelente farmacocinética y fisicoquÍmica preclÍnica (PK ) caracterÍsticas.(S)-Ceralasertib se desarrolla mejorando la solubilidad acuosa y elimina la inhibiciÓn dependiente del tiempo de CYP3A4. (S)-Ceralasertib Chemical Structure
  27. GC46351 (S)-CR8 (S)-CR8 es el isÓmero S de CR8. (S)-CR8 es un inhibidor de CDK potente y selectivo con IC50 de 0,060, 0,080, 0,11, 0,12 y 0,15 μM para CDK2/ciclina E, CDK2/ciclina A, CDK9/ciclina T, CDK5/p25 y CDK1/ciclina B, respectivamente. (S)-CR8 reduce la supervivencia de las células SH-SY5Y (IC50 0,40μM). (S)-CR8 Chemical Structure
  28. GC41737 (S)-Glycyl-H-1152 (hydrochloride)

    Rho Kinase Inhibitor IV

     Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. (S)-Glycyl-H-1152 (hydrochloride) Chemical Structure
  29. GC40145 (S)-Laudanosine

    (+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045

     (S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium. (S)-Laudanosine Chemical Structure
  30. GC41739 (S)-nitro-Blebbistatin

    S(-)7Desmethyl8nitro Blebbistatin

     (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-nitro-Blebbistatin Chemical Structure
  31. GC40121 (Z-DEVD)2-Rh 110 (trifluoroacetate salt)

    (Z-Asp-Glu-Val-Asp)2-Rhodamine 110

     (Z-DEVD)2-Rh 110 is a fluorogenic substrate for caspase-3. (Z-DEVD)2-Rh 110 (trifluoroacetate salt) Chemical Structure
  32. GC41742 (Z-IETD)2-Rh 110 (trifluoroacetate salt)

    (Z-Ile-Glu-Thr-Asp)2-R110, Rhodamine 110 bis-(N-CBZ-IETD)2

     (Z-IETD)2-Rh 110 is a fluorogenic substrate for caspase-8. (Z-IETD)2-Rh 110 (trifluoroacetate salt) Chemical Structure
  33. GC18275 1,2-Dihexadecyl-sn-glycero-3-PC

    1,2-Dihexadecyl-sn-glycero-3-Phosphocholine

     1,2-Dihexadecyl-sn-glycero-3-PC is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions. 1,2-Dihexadecyl-sn-glycero-3-PC Chemical Structure
  34. GC45783 1,2-Dioleoyl-rac-glycerol-13C3 An internal standard for the quantification of 1,2-dioleoyl-rac-glycerol 1,2-Dioleoyl-rac-glycerol-13C3 Chemical Structure
  35. GC46379 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)

    1,2-DOPS, 18:1/18:1-PS; PS(18:1/18:1), 1,2-Dioctadecenoyl-sn-glycero-3-Phosphoserine, 1,2-Dioctadecenoyl-sn-glycero-3-Phosphatidylserine

     La 1,2-dioleoil-sn-glicero-3-PS (sal de sodio) es un sustituto de la fosfoserina/fosfatidilserina. 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt) Chemical Structure
  36. GC41823 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)

    biotin-cap-DPPE

    1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid.

     1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt) Chemical Structure
  37. GC46385 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose A ManNAc analog and building block 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose Chemical Structure
  38. GC19528 1,4-Benzoquinone

    p-Benzoquinone, NSC 36324, p-Quinone

     A toxic metabolite of benzene 1,4-Benzoquinone Chemical Structure
  39. GC18726 1-Methyl-1,4-dihydronicotinamide La 1-metil-1,4-dihidronicotinamida es un derivado de la nicotinamida. 1-Methyl-1,4-dihydronicotinamide Chemical Structure
  40. GC90829 1-Palmitoyl-2-Pyropheophorbide a-sn-glycero-3-PC

    Un conjugado de fosfolípido-porfirina.

     1-Palmitoyl-2-Pyropheophorbide a-sn-glycero-3-PC Chemical Structure
  41. GC49736 10-acetyl Docetaxel

    PNU 101383, 10-acetyl Taxotere

     10-acetyl Docetaxel (10-Acetyl docetaxel) es un anÁlogo de Docetaxel, con actividad anticancerÍgena. Docetaxel es un inhibidor del desensamblaje de microtÚbulos, con actividad antimitÓtica. 10-acetyl Docetaxel Chemical Structure
  42. GC12954 10-DAB (10-Deacetylbaccatin)

    NSC 251677

     An inhibitor of microtubule assembly 10-DAB (10-Deacetylbaccatin) Chemical Structure
  43. GC35044 10-Deacetyl-7-xylosyl paclitaxel El 10-desacetil-7-xilosil paclitaxel es un derivado del paclitaxel (un agente estabilizador de microtÚbulos; mejora la polimerizaciÓn de la tubulina) con caracterÍsticas farmacolÓgicas mejoradas. 10-Deacetyl-7-xylosyl paclitaxel Chemical Structure
  44. GC35045 10-Oxo Docetaxel 10-Oxo Docetaxel (Docetaxel Impureza 1) es un nuevo taxoide que tiene notables propiedades antitumorales y un intermedio de Docetaxel. 10-Oxo Docetaxel Chemical Structure
  45. GC17295 10058-F4 10058-F4 es un inhibidor de c-Myc que previene la dimerizaciÓn y transactivaciÓn de c-Myc-Max de la expresiÓn del gen objetivo de c-Myc. 10058-F4 Chemical Structure
  46. GC63576 10074-A4 10074-A4 es un inhibidor de c-Myc. 10074-A4 podrÍa unirse a c-Myc370-409 en diferentes sitios a lo largo de la cadena peptÍdica. 10074-A4 tiene efectos anticancerÍgenos. 10074-A4 Chemical Structure
  47. GC14918 10074-G5 10074-G5 es un inhibidor de la dimerizaciÓn de c-Myc-Max con un IC50 de 146 μM. 10074-G5 Chemical Structure
  48. GC40448 12(S)-HETE

    12(S)-Hydroxyeicosatetraenoic Acid

    12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.

     12(S)-HETE Chemical Structure
  49. GC40449 12(S)-HETE MaxSpec® Standard 12(S)-HETE is the predominant lipoxygenase product of mammalian platelets. 12(S)-HETE MaxSpec® Standard Chemical Structure
  50. GC26213 13,14-Dihydro-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-14-carbonitrile

    DIHYDROSANGUINARINE

    13,14-Dihydro-13-methyl[1,3]benzodioxolo[5,6-c]-1,3-dioxolo[4,5-i]phenanthridine-14-carbonitrile Chemical Structure
  51. GC46434 13C15-Nivalenol An internal standard for the quantification of nivalenol 13C15-Nivalenol Chemical Structure
  52. GC49390 13C6-4-Nitroaniline

    13C6-p-Nitroaniline

     An internal standard for the quantification of 4-nitroaniline 13C6-4-Nitroaniline Chemical Structure
  53. GC40452 15(S)-HETE MaxSpec® Standard 15(S)-HETE is a major arachidonic acid metabolite from the 15-lipoxygenase pathway. 15(S)-HETE MaxSpec® Standard Chemical Structure
  54. GC46446 15-deoxy-δ12,14-Prostaglandin J2-biotin

    15deoxyΔ12,14PGJ2biotin

     A neuropeptide with diverse biological activities 15-deoxy-δ12,14-Prostaglandin J2-biotin Chemical Structure
  55. GC41110 16-epi Latrunculin B 16-epi Latrunculin B, first isolated from the Red Sea sponge N. 16-epi Latrunculin B Chemical Structure
  56. GC48423 19-O-Acetylchaetoglobosin A

    Chaetoglobosin A Acetate

     La 19-O-acetilquetoglobosina A, un alcaloide del citocalasano, es un metabolito fÚngico aislado originalmente de C. globosum que tiene actividades inhibidoras de la polimerizaciÓn de actina y citotÓxicas. La 19-O-acetilquetoglobosina A es citotÓxica para las células de cÁncer de cuello uterino HeLa. 19-O-Acetylchaetoglobosin A Chemical Structure
  57. GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    dGMP

     2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate) Chemical Structure
  58. GC90819 2,3,7,8-Tetrachlorodibenzofuran

    Un dibenzofurano policlorado y dioxina.

     2,3,7,8-Tetrachlorodibenzofuran Chemical Structure
  59. GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone

    Coenzyme Q0, CoQ0

     La 2,3-dimetoxi-5-metil-p-benzoquinona (CoQ0) es un compuesto de ubiquinona activo oral potente que puede derivarse de Antrodia cinnamomea. 2,3-Dimethoxy-5-methyl-p-benzoquinone Chemical Structure
  60. GC49671 2,3-Oxidosqualene

    (3R,S)-Oxidosqualene, Squalene 2,3-oxide

     An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene Chemical Structure
  61. GC45324 2,5-dimethyl Celecoxib

    DMC

       2,5-dimethyl Celecoxib Chemical Structure
  62. GC49362 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline

    MeIQx

     A food-derived carcinogen 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline Chemical Structure
  63. GC52029 2-Aminoflubendazole

    Hydrolyzed Flubendazole

     El 2-aminoflubendazol es el metabolito de los bencimidazoles. 2-Aminoflubendazole Chemical Structure
  64. GC90840 2-Chloroadenosine-5'-O-diphosphate (sodium salt)

    Un derivado de ADP.

     2-Chloroadenosine-5'-O-diphosphate (sodium salt) Chemical Structure
  65. GC40675 2-deoxy-Artemisinin 2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin. 2-deoxy-Artemisinin Chemical Structure
  66. GC62777 2-Methoxy-4-vinylphenol El 2-metoxi-4-vinilfenol (2M4VP), un inhibidor natural de la germinaciÓn, ejerce potentes efectos antiinflamatorios. 2-Methoxy-4-vinylphenol Chemical Structure
  67. GC15084 2-Methoxyestradiol (2-MeOE2)

    2Hydroxyestradiol 2methyl ether, 2ME2, NSC 659853, Panzem

     2-Methoxyestradiol (2-MeOE2/2-Me) is an HIF-1α inhibitor. 2-Methoxyestradiol (2-MeOE2) Chemical Structure
  68. GC52140 2-Methoxyhydroquinone

    o-Methoxyhydroquinone, MHQ, MOHQ

     2-Methoxyhydroquinone Chemical Structure
  69. GC91133 2-n-Dodecylfuran

    Un intermediario sintético

     2-n-Dodecylfuran Chemical Structure
  70. GC48449 28-(Poc-amino)betulin 28-(Poc-amino)betulin Chemical Structure
  71. GC42161 2H-Cho-Arg (trifluoroacetate salt) 2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. 2H-Cho-Arg (trifluoroacetate salt) Chemical Structure
  72. GC62033 3α-Hydroxy pravastatin sodium

    3α-Isopravastatin, R-416

     3α-La hidroxipravastatina sÓdica es el principal metabolito de la pravastatina. 3α-Hydroxy pravastatin sodium Chemical Structure
  73. GC40618 3',4',7-Trihydroxyisoflavone

    3'-hydroxy Daidzein, 3’,4’,7-THIF

     3',4',7-trihidroxiisoflavona, un metabolito principal de la daidzeÍna, es un inhibidor competitivo de ATP de Cot (Tpl2/MAP3K8) y MKK4. 3',4',7-trihidroxiisoflavona tiene actividades anticancerÍgenas, antiangiogénicas, quimioprotectoras y de eliminaciÓn de radicales libres. 3',4',7-Trihydroxyisoflavone Chemical Structure
  74. GC45332 3'-Dephosphocoenzyme A

    depCoA, Dephospho-CoA

     An intermediate in the biosynthesis of CoA 3'-Dephosphocoenzyme A Chemical Structure
  75. GC18452 3,4-Dichloroisocoumarin

    3,4-DCI

     A serine protease inhibitor 3,4-Dichloroisocoumarin Chemical Structure
  76. GC42239 3,6-diacetoxy Phthalonitrile

    ADB, 1,4-Diacetoxy-2,3-dicyanobenzene, 2,3-Dicyano-1,4-hydroquinone diacetate

     El 3,6-diacetoxi ftalonitrilo es una sonda fluorescente permeable a las células. 3,6-diacetoxy Phthalonitrile Chemical Structure
  77. GC12314 3-(4-Pyridyl)indole

    Rho Kinase Inhibitor III,ROCK Inhibitor III,Rockout

     El 3-(4-piridil)indol (Rockout) es un inhibidor de la Rho-quinasa (ROCK), con una IC50 de 25 μM. 3-(4-Pyridyl)indole Chemical Structure
  78. GC46582 3-Acetyldeoxy Nivalenol-13C17

    3-AcDON-13C17, DON 3-acetate-13C17, Deoxy Nivalenol-3-acetate-13C17

     An internal standard for the quantification of 3-acetyldeoxy nivalenol 3-Acetyldeoxy Nivalenol-13C17 Chemical Structure
  79. GC52129 3-Amino-5-hydroxybenzoic Acid

    AHBA

     3-Amino-5-hydroxybenzoic Acid Chemical Structure
  80. GC15389 360A 360A Chemical Structure
  81. GC10115 360A iodide 360A iodide Chemical Structure
  82. GC14186 3MB-PP1 3MB-PP1, un anÁlogo de purina voluminoso, es un inhibidor de la quinasa 1 similar a Polo (Plk1). 3MB-PP1 Chemical Structure
  83. GC45354 4β-Hydroxywithanolide E

    NSC 212509

     4β-Hydroxywithanolide E, aislado de Physalis peruviana L. 4β-Hydroxywithanolide E Chemical Structure
  84. GC17271 4'-Demethylepipodophyllotoxin

    (-)-4′-Demethylepipodophyllotoxin

     An inhibitor of tubulin polymerization 4'-Demethylepipodophyllotoxin Chemical Structure
  85. GC46606 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline

    4-Aminophenylboronic Acid pinacol ester

     A heterocyclic building block 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline Chemical Structure
  86. GC46635 4-deoxy Nivalenol-13C15

    Vomitoxin-13C15, Deoxynivalenol-13C15, DON-13C15

     An internal standard for the quantification of 4-deoxy nivalenol 4-deoxy Nivalenol-13C15 Chemical Structure
  87. GC18359 4-Epianhydrochlortetracycline (hydrochloride) 4-Epianhydrochlortetracycline is a derivative of tetracycline . 4-Epianhydrochlortetracycline (hydrochloride) Chemical Structure
  88. GC42449 4-Methylumbelliferyl-α-L-Iduronide (free acid)

    4-Methylumbelliferyl-α-L-Idopyranosiduronic Acid, 4-MU-α-IdoA, MU-α-IdoA

     4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-Iduronide (free acid) Chemical Structure
  89. GC49244 4-oxo Isotretinoin

    Ro 22-6595

     An active metabolite of isotretinoin 4-oxo Isotretinoin Chemical Structure
  90. GC52365 4-tert-Octylphenol monoethoxylate

    NSC 5259, OP1EO

     An alkylphenolethoxylate and a degradation product of non-ionic surfactants 4-tert-Octylphenol monoethoxylate Chemical Structure
  91. GC46687 5'-Deoxy-5'-methylthioadenosine-d3

    5'-S-Methylthioadenosine-d3, MTA-d3, Vitamin L2-d3

     A neuropeptide with diverse biological activities 5'-Deoxy-5'-methylthioadenosine-d3 Chemical Structure
  92. GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone

    (±)-δ-(3,4-Dihydroxyphenyl)-γ-Valerolactone, 5-(3',4'-Dihydroxyphenyl)-γ-VL

     An active metabolite of various polyphenols 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone Chemical Structure
  93. GC46681 5-Bromouridine

    (–)-5-Bromouridine, BrU, BrUrd, NSC 38296

     A brominated uridine analog 5-Bromouridine Chemical Structure
  94. GC45357 5-Chlorouracil   5-Chlorouracil Chemical Structure
  95. GC42548 5-hydroxy Saxagliptin (hydrochloride) 5-hydroxy Saxagliptin is a major active metabolite of saxagliptin. 5-hydroxy Saxagliptin (hydrochloride) Chemical Structure
  96. GC41156 5-Octyl D-glutamate

    5-Octyl ester D-glutamatic acid

     5-Octyl D-glutamate, also known as 5-octyl ester D-glutamate, is a stable, cell-permeable molecule that generates free D-glutamate upon hydrolysis of the ester bond by cytoplasmic esterases. 5-Octyl D-glutamate Chemical Structure
  97. GC41423 5-trans Prostaglandin E2

    transDinoprostone, 5,6trans PGE2

     5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1. 5-trans Prostaglandin E2 Chemical Structure
  98. GC42586 6α-hydroxy Paclitaxel

    6α-hydroxy Taxol

     6α-hidroxi Paclitaxel es un metabolito primario de Paclitaxel. 6α-hidroxi Paclitaxel conserva un efecto dependiente del tiempo sobre los polipéptidos transportadores de aniones orgÁnicos 1B1/SLCO1B1 (OATP1B1) con una potencia de inhibiciÓn similar a Paclitaxel, mientras que ya no mostrÓ inhibiciÓn dependiente del tiempo de OATP1B3. 6α-hidroxi Paclitaxel se puede utilizar para la investigaciÓn del cÁncer. 6α-hydroxy Paclitaxel Chemical Structure
  99. GC63958 6α-Hydroxy Paclitaxel-d5 6α-Hydroxy Paclitaxel-d5 es el deuterio etiquetado como 6α-Hydroxy paclitaxel. 6α-Hydroxy paclitaxel es un metabolito primario de Paclitaxel. 6α-Hydroxy paclitaxel conserva un efecto dependiente del tiempo sobre los polipéptidos transportadores de aniones orgÁnicos 1B1/SLCO1B1 (OATP1B1) con una potencia de inhibiciÓn similar a Paclitaxel, mientras que ya no mostrÓ inhibiciÓn dependiente del tiempo de OATP1B3. 6α-Hydroxy paclitaxel se puede utilizar para la investigaciÓn del cÁncer. 6α-Hydroxy Paclitaxel-d5 Chemical Structure
  100. GC45969 6β-hydroxy Eplerenone A major metabolite of eplerenone 6β-hydroxy Eplerenone Chemical Structure
  101. GC46721 6-Chloro-2-fluoropurine

    NSC 37363

     A heterocyclic building block 6-Chloro-2-fluoropurine Chemical Structure

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