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Cell Cycle/Checkpoint

Cell Cycle/Checkpoint

Cell Cycle

Cells undergo a complex cycle of growth and division that is referred to as the cell cycle. The cell cycle consists of four phases, G1 (GAP 1), S (synthesis), G2 (GAP 2) and M (mitosis). DNA replication occurs during S phase. When cells stop dividing temporarily or indefinitely, they enter a quiescent state called G0.

Targets for  Cell Cycle/Checkpoint

Products for  Cell Cycle/Checkpoint

  1. Cat.No. Nombre del producto Información
  2. GC40702 α-D-Galactopyranosylphenyl isothiocyanate

    α-D-Galactopyranosylphenyl isothiocyanate is a chemically activated form of galactose that has been used to prepare various neoglycoproteins, which consist of a glycosylated serum albumin substituted with either fluorescein or methotrexate.

    α-D-Galactopyranosylphenyl isothiocyanate  Chemical Structure
  3. GC41676 (±)-Nornicotine

    DL-Nornicotine, (R,S)-Nornicotine

    (±)-Nornicotine is a metabolite of nicotine that acts as a neuronal nicotinic acetylcholine receptor (nAChR) agonist. (±)-Nornicotine  Chemical Structure
  4. GC49482 (±)-Nornicotine-d4

    DL-Nornicotine-d4, (R,S)-Nornicotine-d4

    An internal standard for the quantification of (±)-nornicotine (±)-Nornicotine-d4  Chemical Structure
  5. GC41684 (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane

    BMC, Vectrase P

    (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane (BMC) is a cyclohexane with two mercaptoacetamido groups. (±)-trans-1,2-Bis(2-mercaptoacetamido)cyclohexane  Chemical Structure
  6. GC40802 (±)12(13)-DiHOME

    Isoleukotoxin diol

    (±)12(13)-DiHOME is the diol form of (±)12(13)-EpOME, a cytochrome P450-derived epoxide of linoleic acid also known as isoleukotoxin.

    (±)12(13)-DiHOME  Chemical Structure
  7. GC41656 (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol

    (±)214,15EG

    2-Arachidonoyl glycerol (2-AG) is an endogenous central cannabinoid (CB1) receptor agonist that is present at relatively high levels in the central nervous system. (±)2-(14,15-Epoxyeicosatrienoyl) Glycerol  Chemical Structure
  8. GC45890 (+)-Abscisic Acid-d6

    (S)​-​(+)​-​Abscisic acid-d6; ABA-d6

    (+)-Ácido abscísico-d6 (ABA-d6) es ácido abscísico marcado con deuterio. (+)-Abscisic Acid-d6  Chemical Structure
  9. GC62728 (1E)-CFI-400437 dihydrochloride El diclorhidrato de (1E)-CFI-400437 es un potente inhibidor de PLK4 (IC50= 0,6 nM) y selectivo frente a otros miembros de la familia PLK (>10 μM). El diclorhidrato de (1E)-CFI-400437 inhibe Aurora A, Aurora B, KDR y FLT-3 con IC50 de 0,37, 0,21, 0,48 y 0,18 μM, respectivamente. Actividad antiproliferativa. (1E)-CFI-400437 dihydrochloride  Chemical Structure
  10. GC49690 (3R,5R)-Rosuvastatin (calcium salt) A potential impurity found in bulk preparations of rosuvastatin (3R,5R)-Rosuvastatin (calcium salt)  Chemical Structure
  11. GC41268 (E)-2-Hexadecenal

    trans-2-Hexadecenal

    Sphingosine-1-phosphate (S1P), a bioactive lipid involved in many signaling processes, is irreversibly degraded by the membrane-bound S1P lyase. (E)-2-Hexadecenal  Chemical Structure
  12. GC41701 (E)-2-Hexadecenal Alkyne (E)-2-Hexadecenal alkyne is an alkyne version of the sphingolipid degradation product (E)-2-hexadecenal that can be used as a click chemistry probe. (E)-2-Hexadecenal Alkyne  Chemical Structure
  13. GC46335 (E)-Fenpyroximate

    Fenpyroximate, NNI-850

    El (E)-fenpiroximato es un potente acaricida. (E)-Fenpyroximate  Chemical Structure
  14. GC10419 (R)-CCG-1423 Rho inhibitor (R)-CCG-1423  Chemical Structure
  15. GC16429 (R)-DRF053 dihydrochloride cdk/CK1 inhibitor,potent and ATP-competitive (R)-DRF053 dihydrochloride  Chemical Structure
  16. GC41719 (R)-nitro-Blebbistatin

    R(-)7Desmethyl8nitro Blebbistatin

    (R)-nitro-Blebbistatin is a more stable form of (+)-blebbistatin, which is the inactive form of (-)-blebbistatin. (R)-nitro-Blebbistatin  Chemical Structure
  17. GC46347 (S)-(+)-Methoprene

    Altosid, d-Methoprene, ZR 2458

    El (S)-metopreno es un análogo de la hormona juvenil que impide que el insecto cambie de pupa a adulto y se usa como insecticida. (S)-(+)-Methoprene  Chemical Structure
  18. GC41557 (S)-3'-amino Blebbistatin

    (-)-3'-amino Blebbistatin, m-amino Blebbistatin, meta-amino Blebbistatin

    (S)-3'-amino Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-amino Blebbistatin  Chemical Structure
  19. GC41484 (S)-3'-hydroxy Blebbistatin

    (-)-3'-hydroxy Blebbistatin, meta-hydroxy-Blebbistatin, m-hydroxy-Blebbistatin

    (S)-3'-hydroxy Blebbistatin is a more stable and less phototoxic form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-3'-hydroxy Blebbistatin  Chemical Structure
  20. GC52192 (S)-4'-nitro-Blebbistatin

    (-)-4'-nitro-Blebbistatin, p-nitro-Blebbistatin, para-nitro-Blebbistatin

    (S)-4'-nitro-Blebbistatin es un inhibidor de miosina II no citotÓxico, fotoestable, fluorescente y especÍfico, utilizado en el estudio del papel especÍfico de la miosina II en estudios fisiolÓgicos, de desarrollo y biolÓgicos celulares. (S)-4'-nitro-Blebbistatin  Chemical Structure
  21. GC14497 (S)-CCG-1423 Rho inhibitor (S)-CCG-1423  Chemical Structure
  22. GC34999 (S)-Ceralasertib

    (S)-AZD6738

    (S)-Ceralasertib ((S)-AZD6738) se extrae de la patente WO2011154737A1, Compuesto II, presenta una IC50 de 2,578 nM.(S)-Ceralasertib es un potente y selectivo inhibidor de ATR de sulfoximina morfolinopirimidina con excelente farmacocinética y fisicoquÍmica preclÍnica (PK ) caracterÍsticas.(S)-Ceralasertib se desarrolla mejorando la solubilidad acuosa y elimina la inhibiciÓn dependiente del tiempo de CYP3A4. (S)-Ceralasertib  Chemical Structure
  23. GC46351 (S)-CR8 (S)-CR8 es el isÓmero S de CR8. (S)-CR8 es un inhibidor de CDK potente y selectivo con IC50 de 0,060, 0,080, 0,11, 0,12 y 0,15 μM para CDK2/ciclina E, CDK2/ciclina A, CDK9/ciclina T, CDK5/p25 y CDK1/ciclina B, respectivamente. (S)-CR8 reduce la supervivencia de las células SH-SY5Y (IC50 0,40μM). (S)-CR8  Chemical Structure
  24. GC41737 (S)-Glycyl-H-1152 (hydrochloride)

    Rho Kinase Inhibitor IV

    Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. (S)-Glycyl-H-1152 (hydrochloride)  Chemical Structure
  25. GC40145 (S)-Laudanosine

    (+)-Laudanosine, L-Laudanosine, L-(+)-Laudanosine, NSC 35045

    (S)-Laudanosine is the (S) enantiomer of laudanosine, a metabolite of the neuromuscular blocking agents atracurium and cisatracurium. (S)-Laudanosine  Chemical Structure
  26. GC41739 (S)-nitro-Blebbistatin

    S(-)7Desmethyl8nitro Blebbistatin

    (S)-nitro-Blebbistatin is a more stable form of (-)-blebbistatin, which is a selective cell-permeable inhibitor of non-muscle myosin II ATPases. (S)-nitro-Blebbistatin  Chemical Structure
  27. GC18275 1,2-Dihexadecyl-sn-glycero-3-PC

    1,2-Dihexadecyl-sn-glycero-3-Phosphocholine

    1,2-Dihexadecyl-sn-glycero-3-PC is a synthetic ether-linked phospholipid containing hexadecyl groups at the sn-1 and sn-2 positions. 1,2-Dihexadecyl-sn-glycero-3-PC  Chemical Structure
  28. GC45783 1,2-Dioleoyl-rac-glycerol-13C3 An internal standard for the quantification of 1,2-dioleoyl-rac-glycerol 1,2-Dioleoyl-rac-glycerol-13C3  Chemical Structure
  29. GC46379 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)

    1,2-DOPS, 18:1/18:1-PS; PS(18:1/18:1), 1,2-Dioctadecenoyl-sn-glycero-3-Phosphoserine, 1,2-Dioctadecenoyl-sn-glycero-3-Phosphatidylserine

    La 1,2-dioleoil-sn-glicero-3-PS (sal de sodio) es un sustituto de la fosfoserina/fosfatidilserina. 1,2-Dioleoyl-sn-glycero-3-PS (sodium salt)  Chemical Structure
  30. GC41823 1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)

    biotin-cap-DPPE

    1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) is a biotinylated phospholipid.

    1,2-Dipalmitoyl-sn-glycero-3-PE-N-(cap biotin) (sodium salt)  Chemical Structure
  31. GC46385 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose A ManNAc analog and building block 1,3,4,6-Tetra-O-acetyl-2-azido-2-deoxy-α-D-Mannopyranose  Chemical Structure
  32. GC19528 1,4-Benzoquinone

    p-Benzoquinone, NSC 36324, p-Quinone

    A toxic metabolite of benzene 1,4-Benzoquinone  Chemical Structure
  33. GC18726 1-Methyl-1,4-dihydronicotinamide La 1-metil-1,4-dihidronicotinamida es un derivado de la nicotinamida. 1-Methyl-1,4-dihydronicotinamide  Chemical Structure
  34. GC49736 10-acetyl Docetaxel

    PNU 101383, 10-acetyl Taxotere

    10-acetyl Docetaxel (10-Acetyl docetaxel) es un anÁlogo de Docetaxel, con actividad anticancerÍgena. Docetaxel es un inhibidor del desensamblaje de microtÚbulos, con actividad antimitÓtica. 10-acetyl Docetaxel  Chemical Structure
  35. GC12954 10-DAB (10-Deacetylbaccatin)

    NSC 251677

    An inhibitor of microtubule assembly 10-DAB (10-Deacetylbaccatin)  Chemical Structure
  36. GC35044 10-Deacetyl-7-xylosyl paclitaxel El 10-desacetil-7-xilosil paclitaxel es un derivado del paclitaxel (un agente estabilizador de microtÚbulos; mejora la polimerizaciÓn de la tubulina) con caracterÍsticas farmacolÓgicas mejoradas. 10-Deacetyl-7-xylosyl paclitaxel  Chemical Structure
  37. GC35045 10-Oxo Docetaxel 10-Oxo Docetaxel (Docetaxel Impureza 1) es un nuevo taxoide que tiene notables propiedades antitumorales y un intermedio de Docetaxel. 10-Oxo Docetaxel  Chemical Structure
  38. GC17295 10058-F4 10058-F4 es un inhibidor de c-Myc que previene la dimerizaciÓn y transactivaciÓn de c-Myc-Max de la expresiÓn del gen objetivo de c-Myc. 10058-F4  Chemical Structure
  39. GC63576 10074-A4 10074-A4 es un inhibidor de c-Myc. 10074-A4 podrÍa unirse a c-Myc370-409 en diferentes sitios a lo largo de la cadena peptÍdica. 10074-A4 tiene efectos anticancerÍgenos. 10074-A4  Chemical Structure
  40. GC14918 10074-G5 10074-G5 es un inhibidor de la dimerizaciÓn de c-Myc-Max con un IC50 de 146 μM. 10074-G5  Chemical Structure
  41. GC40448 12(S)-HETE

    12(S)-Hydroxyeicosatetraenoic Acid

    12(S)-HETE is the predominant lipoxygenase product of mammalian platelets.

    12(S)-HETE  Chemical Structure
  42. GC46434 13C15-Nivalenol An internal standard for the quantification of nivalenol 13C15-Nivalenol  Chemical Structure
  43. GC49390 13C6-4-Nitroaniline

    13C6-p-Nitroaniline

    An internal standard for the quantification of 4-nitroaniline 13C6-4-Nitroaniline  Chemical Structure
  44. GC41110 16-epi Latrunculin B 16-epi Latrunculin B, first isolated from the Red Sea sponge N. 16-epi Latrunculin B  Chemical Structure
  45. GC48423 19-O-Acetylchaetoglobosin A

    Chaetoglobosin A Acetate

    La 19-O-acetilquetoglobosina A, un alcaloide del citocalasano, es un metabolito fÚngico aislado originalmente de C. globosum que tiene actividades inhibidoras de la polimerizaciÓn de actina y citotÓxicas. La 19-O-acetilquetoglobosina A es citotÓxica para las células de cÁncer de cuello uterino HeLa. 19-O-Acetylchaetoglobosin A  Chemical Structure
  46. GC42151 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)

    dGMP

    2'-Deoxyguanosine 5'-monophosphate (dGMP) is used as a substrate of guanylate kinases to generate dGDP, which in turn is phosphorylated to dGTP, a nucleotide precursor used in DNA synthesis. 2'-Deoxyguanosine 5'-monophosphate (sodium salt hydrate)  Chemical Structure
  47. GC40947 2,3-Dimethoxy-5-methyl-p-benzoquinone

    Coenzyme Q0, CoQ0

    La 2,3-dimetoxi-5-metil-p-benzoquinona (CoQ0) es un compuesto de ubiquinona activo oral potente que puede derivarse de Antrodia cinnamomea. 2,3-Dimethoxy-5-methyl-p-benzoquinone  Chemical Structure
  48. GC49671 2,3-Oxidosqualene

    (3R,S)-Oxidosqualene, Squalene 2,3-oxide

    An intermediate in the biosynthesis of sterols 2,3-Oxidosqualene  Chemical Structure
  49. GC45324 2,5-dimethyl Celecoxib

    DMC

      2,5-dimethyl Celecoxib  Chemical Structure
  50. GC49362 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline

    MeIQx

    A food-derived carcinogen 2-Amino-3,8-dimethylimidazo-[4,5-f]-quinoxaline  Chemical Structure
  51. GC52029 2-Aminoflubendazole

    Hydrolyzed Flubendazole

    El 2-aminoflubendazol es el metabolito de los bencimidazoles. 2-Aminoflubendazole  Chemical Structure
  52. GC40675 2-deoxy-Artemisinin 2-deoxy-Artemisinin is an inactive metabolite of the antimalarial agent artemisinin. 2-deoxy-Artemisinin  Chemical Structure
  53. GC15084 2-Methoxyestradiol (2-MeOE2)

    2Hydroxyestradiol 2methyl ether, 2ME2, NSC 659853, Panzem

    2-Methoxyestradiol (2-MeOE2/2-Me) is an HIF-1α inhibitor. 2-Methoxyestradiol (2-MeOE2)  Chemical Structure
  54. GC52140 2-Methoxyhydroquinone

    o-Methoxyhydroquinone, MHQ, MOHQ

    2-Methoxyhydroquinone  Chemical Structure
  55. GC42161 2H-Cho-Arg (trifluoroacetate salt) 2H-Cho-Arg is a steroid-based cationic lipid that contains a 2H-cholesterol skeleton coupled to an L-arginine head group and can be used to facilitate gene transfection. 2H-Cho-Arg (trifluoroacetate salt)  Chemical Structure
  56. GC40618 3',4',7-Trihydroxyisoflavone

    3'-hydroxy Daidzein, 3’,4’,7-THIF

    3',4',7-trihidroxiisoflavona, un metabolito principal de la daidzeÍna, es un inhibidor competitivo de ATP de Cot (Tpl2/MAP3K8) y MKK4. 3',4',7-trihidroxiisoflavona tiene actividades anticancerÍgenas, antiangiogénicas, quimioprotectoras y de eliminaciÓn de radicales libres. 3',4',7-Trihydroxyisoflavone  Chemical Structure
  57. GC45332 3'-Dephosphocoenzyme A

    depCoA, Dephospho-CoA

    An intermediate in the biosynthesis of CoA 3'-Dephosphocoenzyme A  Chemical Structure
  58. GC42239 3,6-diacetoxy Phthalonitrile

    ADB, 1,4-Diacetoxy-2,3-dicyanobenzene, 2,3-Dicyano-1,4-hydroquinone diacetate

    El 3,6-diacetoxi ftalonitrilo es una sonda fluorescente permeable a las células. 3,6-diacetoxy Phthalonitrile  Chemical Structure
  59. GC12314 3-(4-Pyridyl)indole

    Rho Kinase Inhibitor III,ROCK Inhibitor III,Rockout

    El 3-(4-piridil)indol (Rockout) es un inhibidor de la Rho-quinasa (ROCK), con una IC50 de 25 μM. 3-(4-Pyridyl)indole  Chemical Structure
  60. GC46582 3-Acetyldeoxy Nivalenol-13C17

    3-AcDON-13C17, DON 3-acetate-13C17, Deoxy Nivalenol-3-acetate-13C17

    An internal standard for the quantification of 3-acetyldeoxy nivalenol 3-Acetyldeoxy Nivalenol-13C17  Chemical Structure
  61. GC52129 3-Amino-5-hydroxybenzoic Acid

    AHBA

    3-Amino-5-hydroxybenzoic Acid  Chemical Structure
  62. GC15389 360A 360A  Chemical Structure
  63. GC10115 360A iodide 360A iodide  Chemical Structure
  64. GC14186 3MB-PP1 3MB-PP1, un anÁlogo de purina voluminoso, es un inhibidor de la quinasa 1 similar a Polo (Plk1). 3MB-PP1  Chemical Structure
  65. GC45354 4β-Hydroxywithanolide E

    NSC 212509

    4β-Hydroxywithanolide E, aislado de Physalis peruviana L. 4β-Hydroxywithanolide E  Chemical Structure
  66. GC17271 4'-Demethylepipodophyllotoxin

    (-)-4′-Demethylepipodophyllotoxin

    An inhibitor of tubulin polymerization 4'-Demethylepipodophyllotoxin  Chemical Structure
  67. GC46606 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline

    4-Aminophenylboronic Acid pinacol ester

    A heterocyclic building block 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaboran-2yl)aniline  Chemical Structure
  68. GC46635 4-deoxy Nivalenol-13C15

    Vomitoxin-13C15, Deoxynivalenol-13C15, DON-13C15

    An internal standard for the quantification of 4-deoxy nivalenol 4-deoxy Nivalenol-13C15  Chemical Structure
  69. GC18359 4-Epianhydrochlortetracycline (hydrochloride) 4-Epianhydrochlortetracycline is a derivative of tetracycline . 4-Epianhydrochlortetracycline (hydrochloride)  Chemical Structure
  70. GC42449 4-Methylumbelliferyl-α-L-Iduronide (free acid)

    4-Methylumbelliferyl-α-L-Idopyranosiduronic Acid, 4-MU-α-IdoA, MU-α-IdoA

    4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-Iduronide (free acid)  Chemical Structure
  71. GC49244 4-oxo Isotretinoin

    Ro 22-6595

    An active metabolite of isotretinoin 4-oxo Isotretinoin  Chemical Structure
  72. GC52365 4-tert-Octylphenol monoethoxylate

    NSC 5259, OP1EO

    An alkylphenolethoxylate and a degradation product of non-ionic surfactants 4-tert-Octylphenol monoethoxylate  Chemical Structure
  73. GC52227 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone

    (±)-δ-(3,4-Dihydroxyphenyl)-γ-Valerolactone, 5-(3',4'-Dihydroxyphenyl)-γ-VL

    An active metabolite of various polyphenols 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone  Chemical Structure
  74. GC46681 5-Bromouridine

    (–)-5-Bromouridine, BrU, BrUrd, NSC 38296

    A brominated uridine analog 5-Bromouridine  Chemical Structure
  75. GC45357 5-Chlorouracil   5-Chlorouracil  Chemical Structure
  76. GC41156 5-Octyl D-glutamate

    5-Octyl ester D-glutamatic acid

    5-Octyl D-glutamate, also known as 5-octyl ester D-glutamate, is a stable, cell-permeable molecule that generates free D-glutamate upon hydrolysis of the ester bond by cytoplasmic esterases. 5-Octyl D-glutamate  Chemical Structure
  77. GC41423 5-trans Prostaglandin E2

    transDinoprostone, 5,6trans PGE2

    5-trans PGE2 occurs naturally in some gorgonian corals and is a common impurity in commercial lots of PGE1. 5-trans Prostaglandin E2  Chemical Structure
  78. GC42586 6α-hydroxy Paclitaxel

    6α-hydroxy Taxol

    6α-hidroxi Paclitaxel es un metabolito primario de Paclitaxel. 6α-hidroxi Paclitaxel conserva un efecto dependiente del tiempo sobre los polipéptidos transportadores de aniones orgÁnicos 1B1/SLCO1B1 (OATP1B1) con una potencia de inhibiciÓn similar a Paclitaxel, mientras que ya no mostrÓ inhibiciÓn dependiente del tiempo de OATP1B3. 6α-hidroxi Paclitaxel se puede utilizar para la investigaciÓn del cÁncer. 6α-hydroxy Paclitaxel  Chemical Structure
  79. GC45969 6β-hydroxy Eplerenone A major metabolite of eplerenone 6β-hydroxy Eplerenone  Chemical Structure
  80. GC46721 6-Chloro-2-fluoropurine

    NSC 37363

    A heterocyclic building block 6-Chloro-2-fluoropurine  Chemical Structure
  81. GC48721 6-O-Demethyl Griseofulvin

    6-Demethylgriseofulvin

    A metabolite of griseofulvin 6-O-Demethyl Griseofulvin  Chemical Structure
  82. GC15478 6H05 6H05 es un inhibidor selectivo y alostérico del mutante oncogénico K-Ras (G12C). 6H05  Chemical Structure
  83. GC40202 7α-hydroxy Cholesterol-d7

    7α-hydroxycholesterol-d7

    7α-hydroxy Cholesterol-d7 is intended for use as an internal standard for the quantification of 7α-hydroxy cholesterol by GC- or LC-MS.

    7α-hydroxy Cholesterol-d7  Chemical Structure
  84. GC46733 7,12-Dimethylbenz[a]anthracene

    DMBA

    El 7,12-dimetilbenz[a]antraceno tiene actividad cancerÍgena como hidrocarburo aromÁtico policÍclico (HAP). El 7,12-dimetilbenz[a]antraceno se usa para inducir la formaciÓn de tumores en varios modelos de roedores. 7,12-Dimethylbenz[a]anthracene  Chemical Structure
  85. GC35188 7-Epi-10-oxo-docetaxel 7-Epi-10-oxo-docetaxel (Docetaxel Impureza 2) es una impureza de docetaxel detectada por cromatografÍa lÍquida de alta resoluciÓn (HPLC). 7-Epi-10-oxo-docetaxel  Chemical Structure
  86. GC35189 7-Epi-docetaxel 7-Epi-10-oxo-docetaxel (Docetaxel Impureza C; 7-Epitaxotere) es una impureza de docetaxel. 7-Epi-docetaxel  Chemical Structure
  87. GN10625 7-Epitaxol

    7-epi Taxol

    7-Epitaxol  Chemical Structure
  88. GC42610 7-hydroxy Pestalotin

    LL-P880β

    La 7-hidroxi pestalotina (LL-P880β) es un metabolito fúngico. 7-hydroxy Pestalotin  Chemical Structure
  89. GC42616 7-oxo Staurosporine

    BMY 41950, RK-1409

    7-oxo Staurosporine is an antibiotic originally isolated from S.

    7-oxo Staurosporine  Chemical Structure
  90. GC35197 7-xylosyltaxol 7-xilosiltaxol (taxol-7-xilÓsido) es un derivado de taxol (paclitaxel); Paclitaxel se une a la tubulina e inhibe el desmontaje de los microtÚbulos. 7-xylosyltaxol  Chemical Structure
  91. GC52126 8-chloro Caffeine

    NSC 6277

    8-chloro Caffeine  Chemical Structure
  92. GC40844 9-(2,2-Dicyanovinyl)julolidine

    DCVJ, 9-Julolidine Methylene Malononitrile, NSC 160064

    La 9-(2,2-Dicianovinil)julolidina (9-(2,2-Dicianovinil)julolidina), un rotor molecular y un tinte fluorescente Único, se une a la tubulina y la actina y aumenta drÁsticamente la intensidad de su fluorescencia tras la polimerizaciÓn. 9-(2,2-Dicyanovinyl)julolidine  Chemical Structure
  93. GC48986 9-hydroxy Stearic Acid

    9-HSA, 9-hydroxy Octadecanoic Acid

    A hydroxy fatty acid 9-hydroxy Stearic Acid  Chemical Structure
  94. GC42665 AAF-CMK (trifluoroacetate salt)

    NAlaAlaPheCMK, Tripeptidyl Peptidase Inhibitor II

    Tripeptidyl peptidase II (TPPII) is a serine peptidase of the subtilisin-type which removes tripeptides from the free NH2 terminus of oligopeptides. AAF-CMK (trifluoroacetate salt)  Chemical Structure
  95. GC35216 AAPK-25 AAPK-25 es un inhibidor dual Aurora/PLK potente y selectivo con actividad antitumoral, que puede provocar un retraso mitÓtico y detener las células en una prometafase, reflejada por la fosforilaciÓn de la histona H3Ser10 del biomarcador y seguida de un aumento de la apoptosis. AAPK-25 se dirige a Aurora-A, -B y -C con valores de Kd que oscilan entre 23 y 289 nM, asÍ como a PLK-1, -2 y -3 con valores de Kd que oscilan entre 55 y 456 nM. AAPK-25  Chemical Structure
  96. GC25025 Abraxane

    Nab-Paclitaxel

    Abraxane (Nab-Paclitaxel), a novel solvent-free taxane with the binding ratio of Paclitaxel to human serum albumin of 1:9, is an anti-microtubule drug that promotes microtubule aggregation in tubulin dimer and inhibits microtubule depolymerization to stabilize the microtubule system. Abraxane  Chemical Structure
  97. GC15875 ABT-751 (E7010) ABT-751 (E7010)(E 7010) es una nueva sulfonamida antimitÓtica y fijadora de tubulina biodisponible con IC50 de aproximadamente 1,5 y 3,4 μ M en lÍneas celulares de neuroblastoma y no neuroblastoma, respectivamente. ABT-751 (E7010)  Chemical Structure
  98. GC42683 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1). Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp  Chemical Structure
  99. GC52499 Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt) A sensitive substrate for neutrophil elastase Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp (trifluoroacetate salt)  Chemical Structure
  100. GC42684 Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human proteinase 3 (kcat/Km = 1,570 mM-1s-1). Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt)  Chemical Structure
  101. GA20494 Ac-Asp-Glu-Val-Asp-pNA

    Ac-Asp-Glu-Val-Asp-pNA

    The cleavage of the chromogenic caspase-3 substrate Ac-DEVD-pNA can be monitored at 405 nm. Ac-Asp-Glu-Val-Asp-pNA  Chemical Structure

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