Thyroid hormone Receptor

An amino acid building block

pTH (1-34) (rat) is a parathyroid hormone.

pTH-Related Protein (1-34) (human, mouse, rat) is a peptide with a conserved sequence among human, mouse, and rat species. pTH-Related Protein (1-34) shares significant homology with parathyroid hormone (PTH) and binds to the same PTH receptor, participating in various physiological processes.

3,3',5'-Triiodo-L-thyronine is a thyroid hormone generated by deiodination of the prohormone thyroxine.

Thyroid hormone receptor antagonist

Methimazole is an antithyroid agent and has anti-inflammatory activity, with an IC 50 value of 10μM for inhibiting prostaglandin H synthase.

L-Thyroxine is a synthetic thyroid hormone that mimics the natural thyroxine secreted by the thyroid gland and plays a crucial role in regulating metabolism and promoting growth and development. L-Thyroxine is commonly used to treat hypothyroidism and other thyroid-related diseases.

Liothyronine sodium is a potent thyroid hormone receptor TRα and TRβ agonist with Ki values of 2.33nM.

Sobetirome is a selective agonist of the thyroid hormone receptor β (TRβ), with an EC 50 of 0.16μM to TRβ-1.

thyroid hormone analogue

novel orally active TRH analogue

3,5-Diiodothyroacetic acid (diac) is the acetic acid variant of thyroxine.

MGL-3196 is a highly selective and orally active thyroid hormone receptor β (THRβ) agonist with an EC 50 value of 0.21μM.

3,5-Diiodothyropropionic Acid is a synthetic thyroid hormone analog/thyromimetic. 3,5-Diiodothyropropionic Acid binds to thyroid hormone receptors (TRs) with association constants (K a ) of 2.40M -1 and 4.06M⁻¹ for TRα1 and TRβ1.

Perfluorotridecanoic Acid (Perfluorinated Compound (PFC)) is a perfluorinated alkyl acid (PFAA) and a possible organic pollutant

Protirelin (Synthetic thyrotropin-releasing factor) is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.

Thyroxine sulfate (T4 Sulfate) is a thyroid hormone metabolite.

TR antagonist 1 is a high-affinity thyroid hormone receptor (TR) antagonist with IC50s of 36 and 22 nM for TRα and TRβ, respectively.

KAT681 (T0681) is a liver-selective thyromimetic.

PCO371 is an orally active small-molecule full agonist of the PTHR1, which binds to the intracellular interface of PTH1R and the Gs protein.

Eprotirome (KB2115) (KB2115) is a liver-selective thyroid hormone receptor (TR) agonist.

Protirelin Acetate is a highly conserved neuropeptide that exerts the hormonal control of thyroid-stimulating hormone (TSH) levels as well as neuromodulatory functions.

T3-ATA S-isomer is the S-isomer of T3-ATA, which is the active form of the thyroid hormone.