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Urodilatin (Synonyms: ANP 95-126)

Catalog No.GC45130 Copy One-Click Copy Product Info

Urodilatin is a renal natriuretic peptide first isolated from human urine.

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Urodilatin Chemical Structure

Cas No.: 115966-23-9

Size Price Stock Qty
500μg
$747.00
In stock
1mg
$1,343.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of Urodilatin

Urodilatin is a renal natriuretic peptide first isolated from human urine. It is derived from the same precursor as atrial natriuretic peptide in kidney tubular cells and secreted luminally. Urodilatin regulates sodium and water reabsorption in the kidney. While it is not normally found in the circulation, systemic administration of urodilatin has pharmacological effects on renal, cardiovascular, and pulmonary parameters in animals.

Chemical Properties of Urodilatin

Cas No. 115966-23-9 SDF
Synonyms ANP 95-126
Canonical SMILES [H]N[C@]([C@@H](C)O)([H])C(N[C@H](C(N1CCC[C@H]1C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@H](C(N[C@H](C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=
Formula C145H234N52O44S3 M.Wt 3506
Solubility DMF: 25 mg/ml,DMSO: 10 mg/ml,Ethanol: 0.3 mg/ml,PBS (pH 7.2): 10 mg/ml Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Urodilatin

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 285.2 μL 1.4261 mL 2.8523 mL
5 mM 57 μL 285.2 μL 570.5 μL
10 mM 28.5 μL 142.6 μL 285.2 μL
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In vivo Formulation Calculator (Clear solution) of Urodilatin

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Working concentration: mg/ml;

Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

Product Documents

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Reviews

Review for Urodilatin

Average Rating: 5 ★★★★★ (Based on Reviews and 4 reference(s) in Google Scholar.)

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