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ZINC13000658

Catalog No.GC79148 Copy One-Click Copy Product Info

ZINC13000658 is a METTL inhibitor.

Products are for research use only. Not for human use. We do not sell to patients.

ZINC13000658 Chemical Structure

Cas No.: 1324070-76-9

Size Price Stock Qty
5mg
$216.00
In stock
10mg
$346.00
In stock

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Based on customer reviews.

Sample solution is provided at 25 µL, 10mM.



Description of ZINC13000658

ZINC13000658 is a METTL inhibitor. ZINC13000658 exhibits significant anti proliferative activity in various cells and can induce G1 phase cell cycle arrest and apoptosis such as HepG2 ( IC50 = 5.632 µM) and SNU-449 ( IC50 = 6.184 µM) cells. ZINC13000658 may be related to the inhibition of the activity of multiple methyltransferases such as METTL1, 3, 6, 16, 18, etc. ZINC13000658 can be used for research on various types of cancer [1].

References:
[1]. Morshed MN, et al. Identification of novel small molecule inhibitors targeting multiple methyltransferase like proteins against hepatocellular carcinoma. Sci Rep. 2025 Sep 26;15(1):33087.

Chemical Properties of ZINC13000658

Cas No. 1324070-76-9 SDF
Formula C21H19N3O3 M.Wt 361.39
Solubility DMSO: 40 mg/mL (110.68 mM; ultrasonic and warming and heat to 60°C) Storage Store at -20°C
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of ZINC13000658

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1 mg 5 mg 10 mg
1 mM 2.7671 mL 13.8355 mL 27.6709 mL
5 mM 553.4 μL 2.7671 mL 5.5342 mL
10 mM 276.7 μL 1.3835 mL 2.7671 mL
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In vivo Formulation Calculator (Clear solution) of ZINC13000658

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Reviews

Review for ZINC13000658

Average Rating: 5 ★★★★★ (Based on Reviews and 30 reference(s) in Google Scholar.)

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