Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor. When evaluated in animal and clinical models of infections, its antiviral spectrum was shown to uniquely encompass activity against herpes viruses (HSV-1, HSV-2, VZV, CMV, EBV, HHV-6, HHV-7, and HHV-8), hepatitis B virus (HBV), and HIV (HIV-1, HIV-2, SIV, and FIV). Adefovir-associated resistance mutations have not yet been observed in HBV resistance surveillance clinical studies.
Adefovir
Catalog No.: GC42731Purity:>98.00%Synonyms: GS-0393, PMEA
Adefovir is an acyclic nucleoside phosphonate that acts as a reverse transcriptase inhibitor.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 106941-25-7
10 mgIn Stock
$24.00
1
25 mgIn Stock
$45.00
1
50 mgIn Stock
$72.00
1
100 mgIn Stock
$108.00
1
| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10 mg | $24.00 | In Stock | 1 | |
| 25 mg | $45.00 | In Stock | 1 | |
| 50 mg | $72.00 | In Stock | 1 | |
| 100 mg | $108.00 | In Stock | 1 |
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Citations
No citations are currently available for this product. Below are selected publications citing GlpBio products.
Nature641, 529–536 (2025)
Nature628, 630–638 (2024)
Nature632, 686–694 (2024)
Nature618, 1017–1023 (2023)
Nature610, 366–372 (2022)
Cell187(9):2288-2304 (2024)
Cell183(7):1867-1883 (2020)
Science388(6745) (2025)
Science387(6739) (2025)
Science387(6734) (2025)
Cell Research35, 97–116 (2025)
Cell Research34, 683–706 (2024)
Cell Research33, 273–287 (2023)
Cell Research33, 546–561 (2023)
Cell Research33, 904–922 (2023)
Cell Research31, 1291–1307 (2021)
Description
Product Documents
Purity:>98.00%Appearance:A solid
Chemical Properties
CAS No.
106941-25-7
Synonyms
GS-0393, PMEA
SMILES
NC1=C2C(N(CCOCP(O)(O)=O)C=N2)=NC=N1
Molecular Formula
C8H12N5O4P
Molecular Weight
273.2
Solubility
0.1 M NaOH : 10 mg/mL (36.60 mM; ultrasonic and adjust pH to 10 with NaOH)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.
CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility
g/mol
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