Alachlor |
| Catalog No.GC46825 |
An herbicide
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 15972-60-8
Sample solution is provided at 25 µL, 10mM.
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Alachlor is an acetanilide herbicide.1,2,3 It inhibits the growth of Avena seedlings when applied to the root medium by subirrigation at concentrations ranging from 0.1 to 25 mM.1 Alachlor (3.4 kg/hectare) reduces wooly cupgrass (E. villosa) emergence by 85% in corn crop fields.2 It also reduces emergence of broadleaf signalgrass (B. platyphylla) in peanut crops when applied at planting.3 Alachlor (>1 µg/ml) induces sister chromatid exchanges and chromosome aberrations in isolated human peripheral blood lymphocytes.4 In vivo, alachlor (126 mg/kg per day) induces olfactory mucosal tumor formation in rats.5 Formulations containing alachlor have been used for weed control in agriculture.
1.Chang, T.C., Marsh, H.V., Jr., and Jennings, P.H.Effect of alachlor on Avena seedlings: Inhibition of growth and interaction with gibberellic acid and indoleacetic acidPestic. Biochem. Physiol.5(4)323-329(1975) 2.Owen, M.D.K., Hartzler, R.G., and Lux, J.Woolly cupgrass (Eriochloa villosa) control in corn (Zea mays) with chloroacetamide herbicidesWeed Technol.7(4)925-929(1993) 3.Chamblee, R.W., Thompson, L., Jr., and Bunn, T.M.Management of broadleaf signalgrass (Brachiaria platyphylla) in peanuts (Arachis hypogaea) with herbicidesWeed Sci.30(1)40-44(1982) 4.Ribas, G., SurrallÉs, J., Carbonell, E., et al.Genotoxicity of the herbicides alachlor and maleic hydrazide in cultured human lymphocytesMutagenesis11(3)221-227(1996) 5.Genter, M.B., Burman, D.M., and Bolon, B.Progression of alachlor-induced olfactory mucosal tumoursInt. J. Exp. Pathol.83(6)303-308(2002)
| Cas No. | 15972-60-8 | SDF | |
| Canonical SMILES | CCC1=C(N(COC)C(CCl)=O)C(CC)=CC=C1CCC1=C(N(COC)C(CCl)=O)C(CC)=CC=C1 | ||
| Formula | C14H20ClNO2 | M.Wt | 269.8 |
| Solubility | DMF: 30 mg/ml,DMSO: 30 mg/ml | Storage | Store at -20°C,protect from light |
| General tips | Please select the appropriate solvent to prepare the stock solution according to the
solubility of the product in different solvents; once the solution is prepared, please store it in
separate packages to avoid product failure caused by repeated freezing and thawing.Storage method
and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored
at -20°C, please use it within 1 month. To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time. |
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| Shipping Condition | Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request. | ||
| Prepare stock solution | |||
|
1 mg | 5 mg | 10 mg |
| 1 mM | 3.7064 mL | 18.5322 mL | 37.0645 mL |
| 5 mM | 0.7413 mL | 3.7064 mL | 7.4129 mL |
| 10 mM | 0.3706 mL | 1.8532 mL | 3.7064 mL |
Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)
g
μL
Step 2: Enter the in vivo formulation (This is only the calculator, not formulation. Please contact us first if there is no in vivo formulation at the solubility Section.)
Calculation results:
Working concentration: mg/ml;
Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )
Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL ddH2O, mix and clarify.
Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.
Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.
Quality Control & SDS
- View current batch:
- Purity: >95.00%
- COA (Certificate Of Analysis)
- SDS (Safety Data Sheet)
- Datasheet
Average Rating: 5 (Based on Reviews and 22 reference(s) in Google Scholar.)
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