Amyloid β

Salen-manganese complexes;SOD mimetic

Compared to the inner salt, the HCl salt of Aβ42 aggregates more readily at pH 7.4.

Amyloid β-Protein (1-43) is more prone to aggregation and has higher toxic properties than the long-known Aβ1-42.

near-infrared probe that binds to Aβ40 aggregates

Inhibitor of amyloid β42 (Aβ42) fibril assembly

Methoxy-X04 is a fluorescent derivative of Congo Red and Thioflavin T, lacking acidic groups, with a smaller molecular weight and increased lipophilicity.

reduces soluble Aβ40 and Aβ42 levels

APP expression modulator

A pan γ-secretase inhibitor

neuroprotective peptide that binds to amyloid beta (Aβ)

DAPT (GSI-IX) is an orally active γ-secretase inhibitor with IC 50 values of 115nM and 200nM for total amyloid-β (Aβ) and Aβ42, respectively.

5-HT receptor antagonist and partial agonist of adrenergic and dopaminergic receptors

Deferoxamine mesylate is an iron chelator that binds Fe(III) and many other metal cations.

acetylcholinesterase inhibitor

CPHPC is a ligand for serum amyloid P component (SAP) and intends to inhibit and dissociate SAP binding to amyloid fibrils and tangles.

Colivelin (CLN) is A brain-permeable neuroprotective peptide that has effective long-term effects on Aβ deposition, neuronal apoptosis and synaptic plasticity defects in neurodegenerative diseases.

FPS-ZM1 is a RAGE-specific inhibitor, with a K i value of 25nM.

EGFR inhibitor

(R,S)-Anatabine is an important alkaloid component in tobacco that can be used as a specific marker for the detection of tobacco use.

Aβ inhibitor

β-Amyloid (1-42), human TFA is a 42-amino acid peptide.

inhibitor of amyloid-β fibril formation and aggregation

inhibitor of Alzheimer’s disease-associated amyloid β (Aβ) oligomerization and fibrillization

Hoechst 34580 is a DNA dye with a maximum excitation wavelength of 368nm and a maximum emission wavelength of 437nm.