GLPBio

Amyloid β

Amyloid β denotes peptides of 36–43 amino acids result from the APP (amyloid precursor protein) and are involved in Alzheimer's disease as the main component of the amyloid plaques.

Products Related to Amyloid β(118)

  • GC17910 structure
    GC17910Tramiprosate
    CAS: 3687-18-1
    Purity: >98.00%

    maintains Aβ in a non-fibrillar form.

  • GC17921 structure
    GC17921Tolcapone
    CAS: 134308-13-7
    Purity: >98%

    A reversible COMT inhibitor

  • GC17974 structure
    GC17974Latrepirdine dihydrochloride
    CAS: 97657-92-6
    Purity: >98.00%

    Latrepirdine is a neuroactive compound with antagonist activity at histaminergic, α-adrenergic, and serotonergic receptors.

  • GC19053 structure
    GC19053Azeliragon
    CAS: 603148-36-3
    Purity: >98.00%

    Azeliragon is a receptor for advanced glycation end-products (RAGE) antagonist.

  • GC30325 structure
    GC30325β-Amyloid 22-35 (Amyloid β-Protein (22-35))
    CAS: 144189-71-9
    Purity: >98%

    β-Amyloid 22-35 (Amyloid β-Protein (22-35)) is a 14-amino acid peptide fragment that can spontaneously aggregate to form β-sheet structures and exerts significant cytotoxicity on hippocampal neurons.

  • GC30823 structure
    GC30823Edonerpic maleate (T-817 maleate)
    CAS: 519187-97-4
    Purity: >98.50%

    T-817MA [1-{3-[2-(1-Benzothiophen-5-yl)ethoxy] propyl}-3-azetidinol maleate] is a newly synthesized agent for Alzheimer's disease (AD) treatment with neuroprotective effects against toxicity from amyloid-β peptide (Aβ) and actions promoting neurite outgrowth.

  • GC30884 structure
    GC30884LX2343
    CAS: 333745-53-2
    Purity: >99.50%

    An inhibitor of BACE1 and PI3K

  • GC30892 structure
    GC30892Glutaminyl Cyclase Inhibitor 1
    CAS: 2110449-60-8
    Purity: >99.00%

    Glutaminyl Cyclase Inhibitor 1 is a glutaminyl cyclase inhibitor with an IC50 of 0.5 μM.

  • GC30920 structure
    GC30920K 01-162 (K162)
    CAS: 677746-25-7
    Purity: >98%

    K 01-162 (K162) (K162) inhibits the fibril formation of Aβ peptides and eliminates their neurotoxicity.

  • GC30952 structure
    GC309524-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine
    CAS: 566169-98-0
    Purity: >98%

    4-(6-Bromo-2-benzothiazolyl)-N-methylbenzenamine is a potent amyloid imaging agent which binds to Amyloid-β (1-40) with a KD of 1.7 nM.

  • GC31083 structure
    GC31083DWK-1339 (MDR-1339)
    CAS: 1018946-38-7
    Purity: >98.00%

    DWK-1339 (MDR-1339) (DWK-1339) is an orally active and blood-brain-barrier-permeable Aβ-aggregation inhibitor, used in the research of Alzheimer's disease.

  • GC31110 structure
    GC31110Glutaminyl Cyclase Inhibitor 2
    CAS: 1884546-29-5
    Purity: >98%

    Glutaminyl Cyclase Inhibitor 2 is a glutaminyl cyclase inhibitor with an IC50 of 1.23 μM.

  • GC31124 structure
    GC31124BF 227
    CAS: 845647-80-5
    Purity: >98.50%

    BF 227 is a candidate for an amyloid imaging probe for PET, with a Ki of 4.3 nM for Aβ1-42 fibrils.

  • GC31129 structure
    GC31129β-Amyloid 1-16 (Amyloid β-Protein (1-16))
    CAS: 131580-10-4
    Purity: >98.50%

    β-Amyloid 1-16 (Amyloid β-Protein (1-16)) is a β-Amyloid protein fragment that can bind to copper(II) ions.

  • GC31137 structure
    GC31137β-Amyloid 29-40 (Amyloid beta-protein(29-40))
    CAS: 184865-04-1
    Purity: >98%

    β-Amyloid 29-40 (Amyloid beta-protein(29-40)) is a fragment of Amyloid-β peptide.

  • GC31146 structure
    GC31146β-Amyloid (10-35), amide
    CAS: 181427-66-7
    Purity: >98%

    β-Amyloid (10-35), amide is composed of 26 aa (10-35 residues of the Aβ peptide) and is the primary component of the amyloid plaques of Alzheimer's disease.

  • GC31171 structure
    GC31171β-Amyloid 1-28 (Amyloid β-Protein (1-28))
    CAS: 109770-29-8
    Purity: >98%

    β-Amyloid 1-28 (Amyloid β-Protein (1-28)) is a β-Amyloid protein fragment involved in metal binding.

  • GC31179 structure
    GC31179β-Amyloid 31-35
    CAS: 149385-65-9
    Purity: >99.50%

    β-Amyloid 31-35 is the shortest sequence of native Amyloid-β peptide that retains neurotoxic activity.

  • GC31208 structure
    GC312084-(6-Bromo-2-benzothiazolyl)benzenamine
    CAS: 566169-97-9
    Purity: >98%

    4-(6-Bromo-2-benzothiazolyl)benzenamine is a β-amyloid PET (positron emission tomography) tracer that can be used in the diagnosis of neurological diseases, such as Alzheimer's and Down's syndrome.

  • GC31259 structure
    GC31259Aftin-4
    CAS: 866893-90-5
    Purity: >98.00%

    An inducer of Aβ42

  • GC31285 structure
    GC31285MK-3328
    CAS: 1201323-97-8
    Purity: >98%

    MK-3328 is a β-Amyloid PET ligand, which exhibits high binding potency with an IC50 of 10.5 nM.

  • GC33160 structure
    GC33160amyloid P-IN-1
    CAS: 1819986-22-5
    Purity: >99.50%

    amyloid P-IN-1 is used in the research of diseases or disorders wherein depletion of serum amyloid P component (SAP), including amyloidosis, Alzheimer's disease, type 2 diabetes mellitus and osteoarthritis.

  • GC33750 structure
    GC33750BF-168
    CAS: 634911-47-0
    Purity: >99.00%

    BF-168, a candidate probe for PET, is found to specifically recognize both neuritic and diffuse plaques, with a Ki of 6.4 nM for Aβ1-42.

  • GC34232 structure
    GC34232Beta-Amyloid(1-14),mouse,rat
    Purity: >98%