GLPBio

PI3K/Akt/mTOR Signaling

Research Areas

Products Related to PI3K/Akt/mTOR Signaling(719)

  • GC79231 structure
    GC79231RMC-4998 TFA
    Purity: >99.00%

    RMC-4998 TFA is an orally active inhibitor targeting the active or GTP-bound state of the KRAS G12C mutant.

  • GC79241 structure
    GC79241SHY-867
    CAS: 2446484-96-2
    Purity: >99.50%

    SHY-867 is a pan RAS inhibitor.

  • GC79242 structure
    GC79242SHY-855
    CAS: 2446485-15-8
    Purity: >98.50%

    SHY-855 is a pan RAS inhibitor.

  • GC79326 structure
    GC79326Tirzepatide sodium
    Purity: >98.00%

    Tirzepatide sodium (LY3298176 sodium) is a dual glucose-dependent insulinotropic polypeptide ( GIP ) and glucagon-like peptide-1 ( GLP-1 ) receptor agonist.

  • GC79339 structure
    GC79339Anti-CD160 Antibody (MAT 302)
    Purity: >97.00%

    Anti-CD160 Antibody (MAT 302) (CL1-R2) is a human monoclonal antibody targeting CD160.

  • GC79396 structure
    GC79396Anti-CD3 Antibody (UCHT-1)
    Purity: >97.00%

    Anti-CD3 Antibody (UCHT-1) is an antibody targeting CD3.

  • GC79423 structure
    GC79423IL13Rα2 D1
    CAS: 2319573-67-4
    Purity: >99.00%

    IL13Rα2 D1 is an effective IL-13/IL13Rα2 signaling axis inhibitor.

  • GC79430 structure
    GC79430Anti-IL11 Antibody (X203, Mouse IgG)
    Purity: >99.00%

    Anti-IL11 Antibody (X203, Mouse IgG ) is an antibody targeting IL-11.

  • GC79462 structure
    GC79462AZ14289671
    CAS: 3101563-22-5
    Purity: >98.50%

    AZ14289671 is an orally active, blood-brain barrier-penetrant tyrosine kinase ( tyrosine kinase ) inhibitor (TKI) that specifically targets non-small cell lung cancer (NSCLC) harboring EGFR exon 20 insertion mutations ( EGFR Exon20Ins ), while largely sparing wild-type EGFR to reduce off-target toxicities such as rash and diarrhea.

  • GC79463 structure
    GC79463NGI-189
    CAS: 2763063-26-7
    Purity: >99.00%

    NGI‑189 is a selective OST‑A inhibitor.

  • GC79464 structure
    GC79464STA-013
    Purity: >99.00%

    STA-013 is a EphB tyrosine kinase inhibitor.

  • GC79513 structure
    GC79513Lemairamin
    CAS: 29946-61-0
    Purity: >99.50%

    Lemairamin (Wgx-50) is a hydroxylamine compound.

  • GC79519 structure
    GC79519SKF-96365
    CAS: 162849-90-3
    Purity: >99.50%

    SKF-96365 is a TRPC channel antagonist and store-operated calcium entry ( SOCE ) inhibitor.

  • GC79578 structure
    GC79578PrCP-7414
    CAS: 1252037-41-4
    Purity: >99.50%

    PrCP-7414 is a prolyl carboxypeptidase ( PRCP ) inhibitor.

  • GC79709 structure
    GC79709HK2-IN-4
    CAS: 2748366-80-3
    Purity: >99.50%

    HK2-IN-4 is a selective hexokinase 2 ( HK2 ) inhibitor with an IC 50 value of 0.79 μM and a K d value of 0.41 μM.

  • GC79749 structure
    GC79749SHIP1-IN-1
    CAS: 3027375-00-1
    Purity: >99.50%

    SHIP1-IN-1 is an orally active, blood-brain barrier-permeable SHIP1 ligand.

  • GC79759 structure
    GC79759SkQR1 hydroxide
    CAS: 1333381-77-3
    Purity: >98%

    SkQR1 hydroxide is a mitochondrial targeted antioxidant.

  • GC79816 structure
    GC79816Cryptolepine
    CAS: 480-26-2
    Purity: >98%

    Cryptolepine is an orally active multi-potent alkaloid with anti-cancer, anti-bacterial, anti-viral, anti-malarial, anti-inflammatory, anti-hyperglycemic, relieve pain and other properties.

  • GC80851 structure
    GC80851MARY15
    CAS: 3107758-65-3
    Purity: >99.50%

    MARY15 is a pyridinylpiperazine-based derivative of MARY1.

  • GC80852 structure
    GC80852Gedatolisib-d 8
    Purity: >98.50%

    Gedatolisib -d 8 (PKI-587-d 8 ) is the deuterium labeled Gedatolisib.

  • GC80867 structure
    GC80867SM1-71-R
    CAS: 2088180-03-2
    Purity: >98.50%

    SM1-71 -R is a reversible analog o SM1-71.

  • GC80868 structure
    GC80868Antcin K
    CAS: 741268-13-3
    Purity: >98%

    Antcin K is a selective inhibitor targeting the PI3K/Akt, NF-κB, MEK1/2-ERK, p38 and AP-1 pathways.

  • GC80869 structure
    GC80869Calebin A
    CAS: 336784-82-8
    Purity: >98.00%

    Calebin A is a PI3K/Akt/mTOR, MAPK, and NF-κB inhibitor with oral effectiveness.

  • GC80870 structure
    GC80870XL-418
    CAS: 871343-09-8
    Purity: >95.00%

    XL-418 is an orally active dual Akt and p70S6K inhibitor with IC 50 s of 1 nM for Akt1 and 2 nM for p70S6K.