Behavioral Neuroscience

A nicotinic acetylcholine receptor (nAChR) agonist

β-Estradiol-d3 is a deuterated labeling compound of the endogenous estrogen 17β-Estradiol.

A neonicotinoid insecticide

SB 202190 is a potent, selective, and cell-permeable inhibitor of p38 MAP kinases, inhibiting p38α (SAPK2A, MAPK14) and p38β (SAPK2B, MAPK11) with IC50 values of 50 and 100 nM, respectively.

Neuropeptide S is a neuropeptide that is an agonist of the neuropeptide S receptor (NPSR) with an EC50 value of 3.2 nM for the rat peptide to induce intracellular calcium mobilization in HEK293 cells expressing the human receptor.

meta-Fluoxetine is an isomer of fluoxetine that is found as an impurity in fluoxetine preparations.

CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.

R-(-)-α-Methylhistamine (hydrochloride) is a potent, selective and brain-penetrant agonist of H3 histamine receptor, with a Kd of 50.3 nM.

Leteprinim (potassium salt) (AIT-082) is a hypoxanthine derivative neurotrophic agent.

RU-505 is an inhibitor of the interaction between amyloid-β (Aβ) and fibrinogen, with a higher efficacy for inhibiting monomeric forms of Aβ bound to fibrinogen over oligomeric forms.

(2'S)-Nicotine-1-oxide is a metabolite of nicotine .

11β-Prostaglandin F2α (11β-PGF2α) is the primary plasma metabolite of PGD2 in vivo.

S-Adenosyl-L-methionine tosylate (S-Adenosyl methionine tosylate) is produced endogenously from methionine and ATP by action of the enzyme methionine adenosyltransferase and is an important orally active methyl group donor.

8-hydroxy Loxapine (8-OH loxapine) is a metabolite formed when loxapine , an atypical antipsychotic, is metabolized by the cytochrome P450 isoform CYP1A2.

Thiothixene is a typical antipsychotic.

NPC-15437 is a selective protein kinase C (PKC) inhibitor (IC50 = 19 uM).

Leucomethylene blue (Mesylate) is a common reduced form of Methylene Blue, Methylene Blue is a member of the thiazine class of dyes.

(S)-Indoximod (1-Methyl-L-tryptophan) is a novel, orally active IDO Pathway inhibitor (K i =19μM).

TAK-041 is a potent and selective small-molecule G protein-coupled receptor 139 (GPR139) agonist with an EC 50 value of 22nM.

Ginsenoside CK, a secondary ginsenoside biotransformed from major ginsenosides, is more bioavailable and soluble than its parent ginsenosides and holds great significance.

Kynurenic acid-d5 is the deuterium labeled Kynurenic acid.