CAY10649 |
| Catalog No.GC18480 |
5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1272519-89-7
Sample solution is provided at 25 µL, 10mM.
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5-Lipoxygenase (5-LO) catalyzes the biosynthesis of leukotrienes, which are involved in a variety of inflammatory responses, including neutrophil chemotaxis, vascular permeability, and smooth muscle contraction. CAY10649 is a thiazolinone compound that demonstrates direct inhibition of 5-lipoxygenase (5-LO) product formation in intact polymorphonuclear leukocytes (PMNL) (IC50 = 0.28 μM) and a soluble fraction of a S100 PMNL cell lysate (IC50 = 0.09 μM) after stimulation with calcium and arachidonic acid.
Review for CAY10649
Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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