Home>>Signaling Pathways>> Chromatin/Epigenetics>> Citrullination>>CAY10723

CAY10723 (Synonyms: AFM30a, AMF30a)

Catalog No.GC43202

CAY10723 is a potent protein arginine deiminase 2 (PAD2) inhibitor and has excellent PAD2-selectivity.

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CAY10723 Chemical Structure

Cas No.: 2095107-57-4

Size Price Stock Qty
500μg
$170.00
In stock
1mg
$321.00
In stock
5mg
$1,103.00
In stock

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Sample solution is provided at 25 µL, 10mM.

Description Chemical Properties Product Documents Related Products

CAY10723 is an inhibitor of protein arginine deiminase 2 (PAD2) that binds to PAD2 in a target engagement assay (EC50 = 9.5 μM in HEK293/PAD2 cells). It is 1.6-, 47-, and ~15-fold selective for PAD2 over PAD1, PAD3, and PAD4, respectively. CAY10723 inhibits histone H3 citrullination in HEK293/PAD2 cells (EC50 = 0.4 μM).

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Average Rating: 5 ★★★★★ (Based on Reviews and 20 reference(s) in Google Scholar.)

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