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Dihydroartemisinic acid

Katalog-Nr.GC38429 Copy One-Click Copy Product Info

DihydroartemisinsÄure (Dihydroqinghao-SÄure) ist eine biosynthetische Vorstufe des Antimalariamittels Artemisinin.

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Dihydroartemisinic acid Chemische Struktur

Cas No.: 85031-59-0

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1mg
32,00 $
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5mg
45,00 $
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10mg
72,00 $
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20mg
126,00 $
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Sample solution is provided at 25 µL, 10mM.



Description of Dihydroartemisinic acid

Dihydroartemisinic acid (Dihydroqinghao acid), isolated as a natural product from Artemisia annua, is a biosynthetic precursor to the antimalarial agent Artemisinin[1].

[1]. Wallaart TE, et al. Isolation and identification of dihydroartemisinic acid from artemisia annua and its possible role in the biosynthesis of artemisinin. J Nat Prod. 1999 Mar;62(3):430-3.

Chemical Properties of Dihydroartemisinic acid

Cas No. 85031-59-0 SDF
Canonical SMILES OC([C@@H]([C@@]1([H])[C@]2([H])[C@](CCC(C)=C2)([H])[C@H](C)CC1)C)=O
Formula C15H24O2 M.Wt 236.35
Löslichkeit DMF: 20 mg/ml,DMF:PBS(pH 7.2)(1:1): 0.5 mg/ml,DMSO: 10 mg/ml,Ethanol: 16 mg/ml Storage 4°C, protect from light
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Dihydroartemisinic acid

Prepare stock solution
1 mg 5 mg 10 mg
1 mM 4.231 mL 21.1551 mL 42.3101 mL
5 mM 846.2 μL 4.231 mL 8.462 mL
10 mM 423.1 μL 2.1155 mL 4.231 mL
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In vivo Formulation Calculator (Clear solution) of Dihydroartemisinic acid

Step 1: Enter information below (Recommended: An additional animal making an allowance for loss during the experiment)

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 11 reference(s) in Google Scholar.)

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