ML-030 (Synonyms: CID-11757146) |
| Katalog-Nr.GC16072 |
ML-030 ist ein potenter PDE4-Inhibitor mit IC50 von 6,7 nM, 12,9 nM, 48,2 nM, 37,2 nM, 452 nM und 49,2 nM fÜr PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1 bzw. PDE4D2.
Products are for research use only. Not for human use. We do not sell to patients.
Cas No.: 1013750-77-0
Sample solution is provided at 25 µL, 10mM.
;)
,-1-7$$$37316672.jpg');)
;)
;)
$$$36806353.jpg');)
;33(7)%EF%BC%9A546-561$$$37156877.jpg');)
;)
;)
;)
%201124-1138.$$$35908550.jpg');)
%20766-780.$$$37100057.jpg');)
%20418-432.$$$36893736.jpg');)
%EF%BC%9A-240-255.$$$35108512.jpg');)
533-545$$$36543525.jpg');)
%201-13.$$$36600053.jpg');)
;)
ML-030 is a potent PDE4 inhibitor, with IC50 of 6.7 nM, 12.9 nM, 48.2 nM, 37.2 nM, 452 nM and 49.2 nM for PDE4A, PDE4A1, PDE4B1, PDE4B2, PDE4C1,and PDE4D2, respectively.
ML-030 is potent in cell-based assay with an EC50 value of 18.7 nM[1].
References:
[1]. Skoumbourdis AP, et al. Exploration and optimization of substituted triazolothiadiazines and triazolopyridazines as PDE4 inhibitors. Bioorg Med Chem Lett. 2009 Jul 1;19(13):3686-92.
Average Rating: 5 (Based on Reviews and 20 reference(s) in Google Scholar.)
GLPBIO products are for RESEARCH USE ONLY. Please make sure your review or question is research based.
Required fields are marked with *