Reactive Oxygen Species
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Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.
ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.
Products Related to Reactive Oxygen Species(505)
- GC49372Kaempferol 7-neohesperidosideCAS: 17353-03-6Purity: >95.00%
A flavonoid glycoside with antioxidant and anticancer activities
- GC49420Gallic Acid-d2CAS: 294660-92-7Purity: >99.00%
An internal standard for the quantification of gallic acid
- GC49422PAR2 (1-6) amide (human) (trifluoroacetate salt)CAS: 2379569-17-0Purity: >95.00%
A peptide agonist of PAR2
- GC49426Taurine-d4CAS: 342611-14-7Purity: >99.00%
An internal standard for the quantification of taurine
- GC49436L-3-n-ButylphthalideCAS: 3413-15-8Purity: >99.00%
A phthalide with antiplatelet and neuroprotective activities
- GC49486Meglutol-d3CAS: 59060-36-5Purity: >99.00%
An internal standard for the quantification of meglutol
- GC49855Harmalol (hydrochloride hydrate)CAS: 6028-00-8Purity: >98.00%
A β-carboline alkaloid and an active metabolite of harmaline
- GC52027IsolariciresinolCAS: 548-29-8Purity: >98.00%
Isolariciresinol ((+)-Cyclolariciresinol) kann zur Erforschung von Rheuma eingesetzt werden.
- GC52073N-formyl-2-AminophenolCAS: 2843-27-8Purity: >98.00%
A bacterial secondary metabolite with antioxidant activity
- GC52081ChamazuleneCAS: 529-05-5Purity: >98.00%
Chamazulen, eine natÜrliche Verbindung, ist ein antioxidativer Inhibitor der Leukotrien-B4-Bildung.
- GC52190Imidazole Ketone ErastinCAS: 1801530-11-9Purity: >98.00%
Imidazole Ketone Erastin ist ein effektiver und metabolisch stabiler System-xc-Inhibitor und Ferroptose-Induktor.
- GC522275-(3',4'-Dihydroxyphenyl)-γ-ValerolactoneCAS: 21618-92-8Purity: >95.00%
An active metabolite of various polyphenols
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC49372 | Kaempferol 7-neohesperidoside | 17353-03-6 | >95.00% | |
A flavonoid glycoside with antioxidant and anticancer activities | ||||
| GC49420 | Gallic Acid-d2 | 294660-92-7 | >99.00% | |
An internal standard for the quantification of gallic acid | ||||
| GC49422 | PAR2 (1-6) amide (human) (trifluoroacetate salt) | 2379569-17-0 | >95.00% | |
A peptide agonist of PAR2 | ||||
| GC49426 | Taurine-d4 | 342611-14-7 | >99.00% | |
An internal standard for the quantification of taurine | ||||
| GC49436 | L-3-n-Butylphthalide | 3413-15-8 | >99.00% | |
A phthalide with antiplatelet and neuroprotective activities | ||||
| GC49486 | Meglutol-d3 | 59060-36-5 | >99.00% | |
An internal standard for the quantification of meglutol | ||||
| GC49500 | Stobadine | 85202-17-1 | >98.00% | |
A pyridoindole antioxidant | ||||
| GC49521 | MHY553 | 6265-56-1 | >98.00% | |
An agonist of PPARα | ||||
| GC49557 | Cu-GTSM | 68341-14-0 | >95.00% | |
A copper-containing compound with diverse biological activities | ||||
| GC49560 | L6H21 | 24533-47-9 | >98.00% | |
L6H21, ein Chalcone-Derivat, ist ein oral aktiver, potenter und spezifischer Inhibitor der myeloischen Differenzierung 2 (MD-2). | ||||
| GC49597 | Leukotriene B4-d5 | - | >99.00% | |
An internal standard for the quantification of LTB 4 | ||||
| GC49708 | Biliverdin (technical grade) | 114-25-0 | >70.00% | |
A bile pigment | ||||
| GC49790 | Reuterin | 2134-29-4 | >98.00% | |
Reuterin ist ein antimikrobielles Breitbandmittel, das gegen grampositive und gramnegative Bakterien sowie Hefen, Schimmelpilze und Protozoen wirkt. | ||||
| GC49849 | 3-Aminosalicylic Acid | 570-23-0 | >98.00% | |
A salicylic acid derivative | ||||
| GC49855 | Harmalol (hydrochloride hydrate) | 6028-00-8 | >98.00% | |
A β-carboline alkaloid and an active metabolite of harmaline | ||||
| GC49864 | 6-Methylpterin | 708-75-8 | >98.00% | |
A derivative of folic acid | ||||
| GC49868 | D-α-Tocopheryl Quinone | 7559-04-8 | >98.00% | |
An oxidative metabolite of vitamin E | ||||
| GC52007 | N-hydroxylamine Dapsone | 32695-27-5 | >98.00% | |
An active metabolite of dapsone | ||||
| GC52027 | Isolariciresinol | 548-29-8 | >98.00% | |
Isolariciresinol ((+)-Cyclolariciresinol) kann zur Erforschung von Rheuma eingesetzt werden. | ||||
| GC52073 | N-formyl-2-Aminophenol | 2843-27-8 | >98.00% | |
A bacterial secondary metabolite with antioxidant activity | ||||
| GC52081 | Chamazulene | 529-05-5 | >98.00% | |
Chamazulen, eine natÜrliche Verbindung, ist ein antioxidativer Inhibitor der Leukotrien-B4-Bildung. | ||||
| GC52164 | Cu-ATSP | 68341-12-8 | >98.00% | |
Cu-ATSP, ein starker Inhibitor des ferroptotischen Zelltods, ist fast 20-mal stärker als CuATSM. | ||||
| GC52190 | Imidazole Ketone Erastin | 1801530-11-9 | >98.00% | |
Imidazole Ketone Erastin ist ein effektiver und metabolisch stabiler System-xc-Inhibitor und Ferroptose-Induktor. | ||||
| GC52227 | 5-(3',4'-Dihydroxyphenyl)-γ-Valerolactone | 21618-92-8 | >95.00% | |
An active metabolite of various polyphenols | ||||