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Reactive Oxygen Species

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Reactive oxygen species (ROS), such as superoxide anion (O2-), hydrogen peroxide (H2O2), and hydroxyl radical (HO•), consist of radical and non-radical oxygen species formed by the partial reduction of oxygen. Cellular ROS are generated endogenously during mitochondrial oxidative metabolism as well as in cellular response to xenobiotics, cytokines, and bacterial invasion.

ROS also activates MAPK pathways by the direct inhibition of MAPK phosphatases. Through PTEN, the PI3K pathway is subject to reversible redox regulation by ROS generated by growth factor stimulation. The activation of autophagy may be a cellular defense mechanism in response to ROS.

Products Related to Reactive Oxygen Species(505)

  • GC91783 structure
    GC91783FA16
    Purity: >95.00%

    FA16 is a ferroptosis inducer and an inhibitor of the system xc- cystine/glutamate transporter.

  • GC91887 structure
    GC91887Methyl Salicylate-d4
    CAS: 1219802-12-6
    Purity: >99.00%

    Methyl Salicylate-d4 ist zur Verwendung als interner Standard für die Quantifizierung von Methylsalicylat durch GC- oder LC-MS bestimmt.

  • GC91910 structure
    GC91910Ferroptosis Inhibitor D1
    Purity: >98.00%

    Ferroptosis Inhibitor D1 ist ein Radikalfänger und ein Ferroptosehemmer.

  • GC92018 structure
    GC92018N,N′-Diferuloylputrescine
    CAS: 42369-86-8
    Purity: >95.00%

    N,N′-Diferuloylputrescine ist ein Polyamin, das in Z. mays gefunden wurde und vielfältige biologische Aktivitäten hat.

  • GC92043 structure
    GC920439(10)-Nitrooleate
    CAS: 1092676-99-7
    Purity: >95.00%

    9(10)-Nitrooleate ist ein Gemisch der endogenen Lipidsignalmoleküle 9-nitrooleat.

  • GC92088 structure
    GC92088GLP-1 (28-36) amide (trifluoroacetate salt)
    Purity: >98.00%

    Glucagon-ähnliches Peptid 1 GLP-1 (28-36) amide (trifluoroacetate salt) ist ein Peptid und ein aktiver Metabolit des endogenen GLP-1R-Agonisten GLP-1 (7-36)-Amids.

  • GN10006 structure
    GN100063,4-Dihydroxybenzaldehyde
    CAS: 139-85-5
    Purity: >99.50%
  • GN10041 structure
    GN10041Isoquercitrin
    CAS: 21637-25-2
    Purity: >98.50%
  • GN10074 structure
    GN10074Xanthotoxol
    CAS: 2009-24-7
    Purity: >98.00%
  • GN10098 structure
    GN10098Glabridin
    CAS: 59870-68-7
    Purity: >97.00%
  • GN10120 structure
    GN10120Pinocembrin
    CAS: 480-39-7
    Purity: >99.00%

    Pinocembrin is a flavonoid compound and a competitive histidine decarboxylase (HDC) inhibitor.

  • GN10132 structure
    GN10132Schizandrin B
    CAS: 61281-37-6
    Purity: >98.00%

    Schizandrin B is a kind of natural compounds which isolated from Schisandra chinensis , possesses a variety of pharmacokinetic properties, including antioxidant, anti-inflammatory, cardiacprotection and neuroprotection.

  • GN10208 structure
    GN10208Berberine hydrochloride
    CAS: 633-65-8
    Purity: >97.00%

    Berberine hydrochloride ist ein bioaktives Alkaloid aus der Isochinolin-Gruppe. Es stammt aus der Heilpflanze Coptis chinensis, die zu den Hahnenfußgewächsen (Ranunculaceae) gehört. Berberine hydrochloride hat ein breites pharmakologisches Wirkungsspektrum und wird bei Krebs, Entzündungen, Diabetes, Depressionen, Bluthochdruck und verschiedenen Infektionen verwendet.

  • GN10221 structure
    GN10221Berberine
    CAS: 2086-83-1
    Purity: >99.50%

    Berberin (Natürliches Gelb 18) ist ein Alkaloid, das aus der chinesischen Kräutermedizin Huanglian als Antibiotikum isoliert wird. Berberin (Natürliches Gelb 18) induziert die Bildung von reaktiven Sauerstoffverbindungen (ROS) und hemmt die DNA-Topoisomerase.

  • GN10237 structure
    GN10237Protopine
    CAS: 130-86-9
    Purity: >99.50%

    Protopine, an alkaloid derived from Corydalis ternata , inhibits acetylcholinesterase activity with an IC 50 value of 50μM.

  • GN10264 structure
    GN10264Isochlorogenic acid A
    CAS: 2450-53-5
    Purity: >98.00%
  • GN10276 structure
    GN10276Naringenin
    CAS: 480-41-1
    Purity: >98.50%

    Naringenin is a citrus flavonoid compound that can be used to treat cancer and has antioxidant and anti-inflammatory activities.

  • GN10292 structure
    GN10292Silibinin
    CAS: 22888-70-6
    Purity: >98%

    Silibinin is an orally active flavonoid with hepatoprotective and anticancer effects.

  • GN10298 structure
    GN10298Albiflorin
    CAS: 39011-90-0
    Purity: >98.00%

    Albiflorin, a principal monoterpene glycoside, exhibits strong pharmacological effects in combating inflammation, oxidation and apoptosis.

  • GN10308 structure
    GN10308Chlorogenic acid
    CAS: 327-97-9
    Purity: >98.00%

    Chlorogensäure ist eine wichtige phenolische Verbindung in Kaffee und Tee.

  • GN10325 structure
    GN10325Nobiletin
    CAS: 478-01-3
    Purity: >99.00%

    Nobiletin is a polymethoxylated flavone extracted from citrus plants. Nobiletin has a variety of pharmacological effects, including antioxidant, anti-inflammatory, and anti-tumor properties.

  • GN10356 structure
    GN10356Calycosin-7-glucoside
    CAS: 20633-67-4
    Purity: >99.50%
  • GN10388 structure
    GN10388Gallic acid
    CAS: 149-91-7
    Purity: >99.00%

    Gallic acid is a 3,4,5-trihydroxybenzoic acid phenolic compound with antioxidant, anti-inflammatory and antitumor activities.

  • GN10422 structure
    GN10422Echinacoside
    CAS: 82854-37-3
    Purity: >98.00%

    Echinacoside is a phenylethanoid glycoside isolated from Cistanche tubulosa with potent antioxidant and anti-inflammatory effects.