GLPBio

ERK

ERK (extracellular-signal-regulated kinase), also known as MAPK, is involved in the regulation of meiosis, mitosis, and postmitotic functions in differentiated cells.

Products Related to ERK(134)

  • GC81556 structure
    GC81556FZ1 peptide
    Purity: >99.50%

    FZ1 peptide is a cyclic heptapeptide and also an integrin αvβ3 agonist.

  • GC81572 structure
    GC81572Glutathione trisulfide TFA
    Purity: >99.00%

    Glutathione trisulfide TFA (GSSSG TFA) is an orally active, blood-brain barrier permeable neuroprotective agent.

  • GC81673 structure
    GC81673UE01
    CAS: 486440-74-8
    Purity: >98%

    UE01 is an orally active, selective small-molecule modulator targeting both ULK1/ERK1/2.

  • GC81682 structure
    GC81682Sialorphin TFA
    Purity: >97.00%

    Sialorphin TFA is a neutral endopeptidase ( NEP ) and aminopeptidase N ( APN ) inhibitor that responds to androgen signals.

  • GC81731 structure
    GC81731Hericene A
    CAS: 157207-54-0
    Purity: >98.50%

    Hericene A is an orally active aromatic hericene derivative.

  • GC81771 structure
    GC81771RANKL-IN-1 formate
    Purity: >99.50%

    RANKL-IN-1 formate is a selective receptor activator of nuclear factor-κB ligand inhibitor ligand ( RANKL ) inhibitor with a K D value of 7.6 μM.

  • GF10303 structure
    GF10303Lipoteichoic acid
    CAS: 56411-57-5

    Lipoteichoic acid is a teichoic acid predominantly located in the cell walls of Gram-positive bacteria, widely involved in stimulating immune responses and cellular signaling pathways.

  • GN10267 structure
    GN10267Loureirin B
    CAS: 119425-90-0
    Purity: >99.00%
  • GN10481 structure
    GN10481Corynoxeine
    CAS: 630-94-4
    Purity: >99.50%
  • GN10494 structure
    GN10494Astragaloside IV
    CAS: 84687-43-4
    Purity: >98.00%

    Astragaloside IV, an active component isolated from Astragalus membranaceus, can protect the myocardium against ischemia/reperfusion injury and Inhibits HAdV-3 replication and reduces HAdV-3-induced apoptosis.

  • GN10664 structure
    GN10664Honokiol
    CAS: 35354-74-6
    Purity: >98.50%

    Honokiol is a natural bisphenol chemical with multiple biological activities. It targets multiple signaling molecules and has effective antioxidant, anti-inflammatory, anti-angiogenic and anti-cancer activities. It also has broad-spectrum antibacterial and anti-human immunodeficiency virus (HIV) activities.

  • GN10752 structure
    GN10752Pachymic acid
    CAS: 29070-92-6
    Purity: >98.00%
  • GC17031 structure
    GC17031VRT752271
    CAS: 869886-67-9
    Purity: >99.50%

    VRT752271 (BVD-523; VRT752271) ist ein potenter, oral aktiver, hochselektiver, ATP-kompetitiver und reversibler kovalenter Inhibitor von ERK1/2-Kinasen mit einem IC50 von <0,3 nM gegen ERK2. VRT752271 (BVD-523; VRT752271) hemmt die phosphorylierte ERK2 (pERK) und die nachgeschaltete Kinase RSK (pRSK) in einer A375-Melanom-Zelllinie.

  • GC10647 structure
    GC10647FR 180204
    CAS: 865362-74-9
    Purity: >98.00%

    FR 180204 ist ein ATP-kompetitiver und selektiver ERK-Inhibitor. FR 180204 hemmt ERK1 und ERK2 mit IC50-Werten von 0,51 μM (Ki=0,31 μM) bzw. 0,33 μM (Ki=0,14 μM).