Obesity, Appetite Control & Diabetes
Obesity, Appetite Control & Diabetes
Satiety, appetite, and craving are CNS drives, whereas metabolism and energy utilization are peripheral endocrine actions.
Stephen M. Stahl, M.D., Ph.D. read more
Research Areas
Products Related to Obesity, Appetite Control & Diabetes(354)
- GC44518Osteocalcin (1-49) (human) (trifluoroacetate salt)CAS: 136461-80-8Purity: >95.00%
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone.
- GC44524Oxyntomodulin (bovine, porcine) (trifluoroacetate salt)Purity: >95.00%
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut.
- GC44544Palmitoleic Acid (sodium salt)CAS: 6610-24-8Purity: >95.00%
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue.
- GC44598Peptide YY (human) (trifluoroacetate salt)Purity: >95.00%
Peptide YY (human) (trifluoroacetate salt) is a peptide hormone secreted by intestinal L cells.
- GC44645Pioglitazone (potassium salt)CAS: 1266523-09-4Purity: >98.00%
Pioglitazon (U 72107) Kalium ist ein oral aktives und selektives PPARγ (Peroxisom-Proliferator-aktivierter Rezeptor)-Agonist mit hoher AffinitÄtsbindung an PPARγ LigandenbindungsdomÄne mit EC50 von 0,93 μM und 0,99 μM fÜr menschliches bzw. Maus-PPARγ.
- GC44660PlatensimycinCAS: 835876-32-9Purity: >95.00%
Platensimycin (PTM) is an antibiotic produced by S.
- GC44775PTP1B InhibitorCAS: 765317-72-4Purity: >98.00%
PTP1B Inhibitor ist ein nicht-kompetitiver allosterischer Inhibitor der Proteintyrosinphosphatase PTP1B mit einem IC50 von 8 μM.
- GC44811Remogliflozin etabonateCAS: 442201-24-3Purity: >99.00%
Remogliflozinetabonat (GSK189075) ist ein oral aktiver, selektiver und niedrigaffiner Natriumglucose-Cotransporter (SGLT2)-Inhibitor mit Ki-Werten von 1,95 μM, 2,14 μM, 43,1 μM, 8,57 μM fÜr hSGLT2, rSGLT2, hSGLT1 bzw. rSGLT1.
- GC44851Rosiglitazone (potassium salt)CAS: 316371-84-3Purity: >98.00%
Rosiglitazon (BRL 49653)-Kalium ist ein oral aktives selektives PPARγ Agonist (EC50: 60 nM, Kd: 40 nM).
- GC44895Sitagliptin N-Sulfate (sodium salt)CAS: 2470126-25-9Purity: >95.00%
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
- GC44914Somatostatin-14 (acetate)CAS: 54472-66-1Purity: >98.00%
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin.
- GC45139Vapreotide (trifluoroacetate salt)Purity: >95.00%
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay).
- GC45144Vildagliptin carboxylic acid metabolite (trifluoroacetate salt)CAS: 565453-41-0Purity: >98.00%
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans.
- GC45186ZLN005 (hydrochloride)Purity: >98.00%
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis.
- GC45252(-)-Sitagliptin Carbamoyl GlucuronideCAS: 940002-59-5Purity: >90.00%
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC44518 | Osteocalcin (1-49) (human) (trifluoroacetate salt) | 136461-80-8 | >95.00% | |
Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. | ||||
| GC44524 | Oxyntomodulin (bovine, porcine) (trifluoroacetate salt) | - | >95.00% | |
Oxyntomodulin, also known as glucagon-37, is a 37-amino acid peptide produced in bovine and porcine gut. | ||||
| GC44529 | P053 | 2748196-63-4 | >97.00% | |
P053 ist ein potenter, nicht kompetitiver und selektiver Inhibitor der Ceramidsynthase 1 (CerS1) mit einem IC50 von 0,5 μM. | ||||
| GC44544 | Palmitoleic Acid (sodium salt) | 6610-24-8 | >95.00% | |
Palmitoleic acid is an ω-7 monounsaturated fatty acid that is a common constituent of the triglycerides of human adipose tissue. | ||||
| GC44598 | Peptide YY (human) (trifluoroacetate salt) | - | >95.00% | |
Peptide YY (human) (trifluoroacetate salt) is a peptide hormone secreted by intestinal L cells. | ||||
| GC44645 | Pioglitazone (potassium salt) | 1266523-09-4 | >98.00% | |
Pioglitazon (U 72107) Kalium ist ein oral aktives und selektives PPARγ (Peroxisom-Proliferator-aktivierter Rezeptor)-Agonist mit hoher AffinitÄtsbindung an PPARγ LigandenbindungsdomÄne mit EC50 von 0,93 μM und 0,99 μM fÜr menschliches bzw. Maus-PPARγ. | ||||
| GC44660 | Platensimycin | 835876-32-9 | >95.00% | |
Platensimycin (PTM) is an antibiotic produced by S. | ||||
| GC44775 | PTP1B Inhibitor | 765317-72-4 | >98.00% | |
PTP1B Inhibitor ist ein nicht-kompetitiver allosterischer Inhibitor der Proteintyrosinphosphatase PTP1B mit einem IC50 von 8 μM. | ||||
| GC44811 | Remogliflozin etabonate | 442201-24-3 | >99.00% | |
Remogliflozinetabonat (GSK189075) ist ein oral aktiver, selektiver und niedrigaffiner Natriumglucose-Cotransporter (SGLT2)-Inhibitor mit Ki-Werten von 1,95 μM, 2,14 μM, 43,1 μM, 8,57 μM fÜr hSGLT2, rSGLT2, hSGLT1 bzw. rSGLT1. | ||||
| GC44851 | Rosiglitazone (potassium salt) | 316371-84-3 | >98.00% | |
Rosiglitazon (BRL 49653)-Kalium ist ein oral aktives selektives PPARγ Agonist (EC50: 60 nM, Kd: 40 nM). | ||||
| GC44895 | Sitagliptin N-Sulfate (sodium salt) | 2470126-25-9 | >95.00% | |
Sitagliptin N-sulfate is a phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC44914 | Somatostatin-14 (acetate) | 54472-66-1 | >98.00% | |
Somatostatin-14 is a natural cyclic peptide hormone derived from the preprohormone, somatostatin. | ||||
| GC44954 | Stevioside (hydrate) | - | >95.00% | |
Stevioside is a natural non-caloric sweetener. | ||||
| GC45139 | Vapreotide (trifluoroacetate salt) | - | >95.00% | |
Vapreotide is a peptide neurokinin-1 receptor (NK1) antagonist and analog of somatostatin (IC50 = 330 nM in a radioligand binding assay). | ||||
| GC45144 | Vildagliptin carboxylic acid metabolite (trifluoroacetate salt) | 565453-41-0 | >98.00% | |
Vildagliptin carboxylic acid metabolite is the major metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor vildagliptin in humans. | ||||
| GC45164 | WWL229 | 1338575-28-2 | >98.00% | |
WWL229 ist ein selektiver Inhibitor der Carboxylesterase 3 (Ces3) mit einem IC50 von 1,94 μM. | ||||
| GC45186 | ZLN005 (hydrochloride) | - | >98.00% | |
Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a tissue-specific and inducible transcriptional coactivator for several nuclear receptors and plays a key role in energy metabolism, hepatic gluconeogenesis, and cholesterol homoeostasis. | ||||
| GC45252 | (-)-Sitagliptin Carbamoyl Glucuronide | 940002-59-5 | >90.00% | |
(-)-Sitagliptin carbamoyl glucuronide is a minor phase II metabolite of the dipeptidyl peptidase 4 (DPP-4) inhibitor (-)-sitagliptin. | ||||
| GC45277 | (±)-Camphene | 79-92-5 | >99.50% | |
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| GC45315 | 1-Palmitoyl-d9-2,3-Dipalmitoyl-sn-glycerol | 2738376-70-8 | >99.00% | |
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| GC45320 | 1-Stearoyl-3-Oleoyl-rac-glycerol | 18266-27-8 | >98.00% | |
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| GC45379 | Alloxan (hydrate) | 2244-11-3 | >98.00% | |
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| GC45490 | Kisspeptin-54 (human) (trifluoroacetate salt) | - | >95.00% | |
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| GC45506 | MD001 | 2254605-76-8 | >90.00% | |
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