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| Pack Size | Price | Availability | Quantity | Action |
|---|---|---|---|---|
| 10mM (in 1mL DMSO) | $22.00 | In Stock | 1 | |
| 5mg | $20.00 | In Stock | 1 | |
| 10mg | $34.00 | In Stock | 1 | |
| 25mg | $66.00 | In Stock | 1 | |
| 50mg | $106.00 | In Stock | 1 | |
| 100mg | $166.00 | In Stock | 1 |
NKL 22 is a HDAC inhibitor. The value of IC 50 is 78 uM NKL 22 increase frataxin protein concentrationsNKL 22 inhibitors increase FXN mRNA in FRDA lymphocytes.HDAC inhibitors act directly on FXN. [1]
[1]. D Herman et al. Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. Nat Chem Biol, 2006 Oct, 2(10):551-8.