Innate Immunity
Products Related to Innate Immunity(566)
- GC419861-Arachidonoyl Lysophosphatidic Acid (ammonium salt)CAS: 799268-65-8Purity: >95.00%
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position.
- GC419981-Methyl-4-imidazoleacetic Acid (hydrochloride)CAS: 35454-39-8Purity: >95.00%
1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine.
- GC420261-Palmitoyl-2-hydroxy-sn-glycero-3-PCCAS: 17364-16-8Purity: >99.50%
Le 1-palmitoyl-2-hydroxy-sn-glycéro-3-PC est un LPC gonadique abondant (lysophosphatidylcholine).
- GC420351-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerolCAS: 2190-28-5Purity: >98.00%
1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic, stearic, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively.
- GC420802'2'-cGAMP (sodium salt)CAS: 1465774-27-9Purity: >98.00%
2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds.
- GC4208220-carboxy Leukotriene B4CAS: 80434-82-8Purity: >97.00%
20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils.
- GC421232-Aminopurine (hydrochloride)CAS: 1428126-74-2Purity: >98.00%
La 2-aminopurine (chlorhydrate) est un analogue fluorescent de la guanosine.
- GC421352-chloro Palmitic AcidCAS: 19117-92-1Purity: >95.00%
L'acide 2-chloro palmitique, un médiateur lipidique inflammatoire, interfère avec la palmitoylation des protéines, induit des marqueurs de stress ER, réduit la teneur en ATP ER et active la transcription et la sécrétion d'IL-6 ainsi que d'IL-8.2-chloro L'acide palmitique perturbe la mitochondrie potentiel membranaire et induit le clivage de la procaspase-3 et de la PARP. L'acide palmitique 2-chloro peut traverser la barrière hémato-encéphalique (BBB) et compromettre les fonctions ER et mitochondriales dans la lignée cellulaire endothéliale du cerveau humain hCMEC/D3.
- GC421362-chloro Stearic AcidCAS: 56279-49-3Purity: >95.00%
2-chloro Stearic acid is a bioactive fatty acid that accumulates in primary human monocytes and neutrophils as well as murine neutrophils stimulated with phorbol 12-myristate 13-acetate.
- GC422423'-sulfo Galactosylsphingosine (ammonium salt)CAS: 1246681-32-2Purity: >98.00%
3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group.
- GC422513-Bromotyrosine (trifluoroacetate salt)CAS: 2320428-62-2Purity: >95.00%
3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response.
- GC422523-Bromotyrosine-13C9,15N (trifluoroacetate salt)Purity: >98.00%
3-Bromotyrosine-13C9,15N is intended for use as an internal standard for the quantification of 3-bromotyrosine by GC- or LC-MS.
- GC423384-Aminobenzoic Acid hydrazideCAS: 5351-17-7Purity: >99.00%
L'hydrazide d'acide 4-aminobenzoÏque est un inhibiteur irréversible de la myéloperoxydase MPO avec une IC50 de 0,3 μM.
- GC423694-Deoxypyridoxine (hydrochloride)CAS: 148-51-6Purity: >98.00%
4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities.
- GC423744-epi-Chlortetracycline (hydrochloride)CAS: 101342-45-4Purity: >90.00%
Chlortetracycline is an analog of tetracycline, a broad spectrum antibiotic.
- GC426238-BromoguanosineCAS: 4016-63-1Purity: >98.00%
8-Bromoguanosine is a brominated derivative of guanosine.
- GC42683Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnpCAS: 824405-61-0Purity: >95.00%
Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1).
- GC42684Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt)Purity: >98.50%
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) est un peptide modifié contenant des groupes de transfert d'énergie par résonance de fluorescence (FRET).
- GC42685Ac-ANW-AMCCAS: 2357123-49-8Purity: >95.00%
Ac-ANW-AMC est un substrait fluorescent pour la sous-unité β5i (LMP7/PSMB8) du protéasome 20S immunitaire, avec une longueur d'onde excitation maximale de λEm=345nm et une longueur d'onde d'émission maximale de λEm=445nm.
- GC42706Ac-IEPD-AMC (trifluoroacetate salt)Purity: >98.00%
Ac-IEPD-AMC is a fluorogenic substrate for granzyme B.
- GC42739Adrenomedullin (1-50) amide (rat) (trifluoroacetate salt)Purity: >95.00%
Adrenomedullin (1-50) is a peptide hormone with RNA expressed in rat adrenal glands, lung, kidney, heart, and spleen, as well as in the duodenum and submandibular glands.
- GC42740Adrenomedullin (1-52) (human) (trifluoroacetate salt)Purity: >95.00%
Adrenomedullin (1-52) is a peptide with diverse biological activities.
- GC42763Alamethicin F50CAS: 56165-93-6Purity: >98.00%
Alamethicin F50 is a peptaibol isolated from Trichoderma.
- GC42824APC 366 (trifluoroacetate salt)Purity: >95.00%
APC 366 is a mast cell tryptase inhibitor (Ki = 7.1 μM for human recombinant enzyme).
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC41986 | 1-Arachidonoyl Lysophosphatidic Acid (ammonium salt) | 799268-65-8 | >95.00% | |
1-Arachidonoyl lysophosphatidic acid is a phospholipid containing arachidonic acid at the sn-1 position. | ||||
| GC41998 | 1-Methyl-4-imidazoleacetic Acid (hydrochloride) | 35454-39-8 | >95.00% | |
1-Methyl-4-imidazoleacetic acid (MIMA) is a stable metabolite of histamine that is produced by the oxidation of the primary metabolite, N-methylhistamine. | ||||
| GC42026 | 1-Palmitoyl-2-hydroxy-sn-glycero-3-PC | 17364-16-8 | >99.50% | |
Le 1-palmitoyl-2-hydroxy-sn-glycéro-3-PC est un LPC gonadique abondant (lysophosphatidylcholine). | ||||
| GC42035 | 1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol | 2190-28-5 | >98.00% | |
1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic, stearic, and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. | ||||
| GC42080 | 2'2'-cGAMP (sodium salt) | 1465774-27-9 | >98.00% | |
2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. | ||||
| GC42082 | 20-carboxy Leukotriene B4 | 80434-82-8 | >97.00% | |
20-carboxy LTB4 is a metabolite of LTB4 in human neutrophils. | ||||
| GC42123 | 2-Aminopurine (hydrochloride) | 1428126-74-2 | >98.00% | |
La 2-aminopurine (chlorhydrate) est un analogue fluorescent de la guanosine. | ||||
| GC42135 | 2-chloro Palmitic Acid | 19117-92-1 | >95.00% | |
L'acide 2-chloro palmitique, un médiateur lipidique inflammatoire, interfère avec la palmitoylation des protéines, induit des marqueurs de stress ER, réduit la teneur en ATP ER et active la transcription et la sécrétion d'IL-6 ainsi que d'IL-8.2-chloro L'acide palmitique perturbe la mitochondrie potentiel membranaire et induit le clivage de la procaspase-3 et de la PARP. L'acide palmitique 2-chloro peut traverser la barrière hémato-encéphalique (BBB) et compromettre les fonctions ER et mitochondriales dans la lignée cellulaire endothéliale du cerveau humain hCMEC/D3. | ||||
| GC42136 | 2-chloro Stearic Acid | 56279-49-3 | >95.00% | |
2-chloro Stearic acid is a bioactive fatty acid that accumulates in primary human monocytes and neutrophils as well as murine neutrophils stimulated with phorbol 12-myristate 13-acetate. | ||||
| GC42242 | 3'-sulfo Galactosylsphingosine (ammonium salt) | 1246681-32-2 | >98.00% | |
3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. | ||||
| GC42251 | 3-Bromotyrosine (trifluoroacetate salt) | 2320428-62-2 | >95.00% | |
3-Bromotyrosine is a product of protein oxidation found after activation of eosinophils during an allergic response. | ||||
| GC42252 | 3-Bromotyrosine-13C9,15N (trifluoroacetate salt) | - | >98.00% | |
3-Bromotyrosine-13C9,15N is intended for use as an internal standard for the quantification of 3-bromotyrosine by GC- or LC-MS. | ||||
| GC42338 | 4-Aminobenzoic Acid hydrazide | 5351-17-7 | >99.00% | |
L'hydrazide d'acide 4-aminobenzoÏque est un inhibiteur irréversible de la myéloperoxydase MPO avec une IC50 de 0,3 μM. | ||||
| GC42369 | 4-Deoxypyridoxine (hydrochloride) | 148-51-6 | >98.00% | |
4-Deoxypyridoxine (4-DPD) is a vitamin B6 antimetabolite with diverse biological activities. | ||||
| GC42374 | 4-epi-Chlortetracycline (hydrochloride) | 101342-45-4 | >90.00% | |
Chlortetracycline is an analog of tetracycline, a broad spectrum antibiotic. | ||||
| GC42623 | 8-Bromoguanosine | 4016-63-1 | >98.00% | |
8-Bromoguanosine is a brominated derivative of guanosine. | ||||
| GC42683 | Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp | 824405-61-0 | >95.00% | |
Abz-Ala-Pro-Glu-Glu-Ile-Met-Arg-Arg-Gln-EDDnp is a fluorescence-quenched peptide substrate for human neutrophil elastase (kcat/Km = 531 mM-1s-1). | ||||
| GC42684 | Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) | - | >98.50% | |
Abz-Val-Ala-Asp-Nva-Arg-Asp-Arg-Gln-EDDnp (trifluoroacetate salt) est un peptide modifié contenant des groupes de transfert d'énergie par résonance de fluorescence (FRET). | ||||
| GC42685 | Ac-ANW-AMC | 2357123-49-8 | >95.00% | |
Ac-ANW-AMC est un substrait fluorescent pour la sous-unité β5i (LMP7/PSMB8) du protéasome 20S immunitaire, avec une longueur d'onde excitation maximale de λEm=345nm et une longueur d'onde d'émission maximale de λEm=445nm. | ||||
| GC42706 | Ac-IEPD-AMC (trifluoroacetate salt) | - | >98.00% | |
Ac-IEPD-AMC is a fluorogenic substrate for granzyme B. | ||||
| GC42739 | Adrenomedullin (1-50) amide (rat) (trifluoroacetate salt) | - | >95.00% | |
Adrenomedullin (1-50) is a peptide hormone with RNA expressed in rat adrenal glands, lung, kidney, heart, and spleen, as well as in the duodenum and submandibular glands. | ||||
| GC42740 | Adrenomedullin (1-52) (human) (trifluoroacetate salt) | - | >95.00% | |
Adrenomedullin (1-52) is a peptide with diverse biological activities. | ||||
| GC42763 | Alamethicin F50 | 56165-93-6 | >98.00% | |
Alamethicin F50 is a peptaibol isolated from Trichoderma. | ||||
| GC42824 | APC 366 (trifluoroacetate salt) | - | >95.00% | |
APC 366 is a mast cell tryptase inhibitor (Ki = 7.1 μM for human recombinant enzyme). | ||||