PI3K/Akt/mTOR Signaling
Research Areas
Products Related to PI3K/Akt/mTOR Signaling(719)
- GC74025PIKfyve-IN-3Purity: >99.00%
PIKfyve-IN-3 (composé L22) a une interaction significative avec la kinase pikfyve avec une valeur de KD de 0,47 nm.
- GC74026DNA-PK-IN-12CAS: 2792146-91-7Purity: >99.00%
DNA-PK-IN-12 (composé 31t) est un inhibiteur actif de l'ADN - PK par voie orale avec une CI50 de 0,1 nm.
- GC74029ASCT2-IN-1CAS: 3032651-18-3Purity: >98.00%
ASCT2-IN-1 (composé 20k) est un inhibiteur d’asct2 avec des valeurs de ci50 de 5,6 μM et 3,5 μM dans les cellules A549 et HEK293, respectivement.
- GC74030ASCT2-IN-2Purity: >99.00%
ASCT2-IN-2 (composé 25e) est un inhibiteur d’asct2 avec une ci50 de 5,14 μM.
- GC74261(R)-(+)-O-DemethylbuchenavianineCAS: 1364123-68-1Purity: >98.00%
(R)-(+)-O-Demethylbuchenavianine est un inhibiteur des kinases CDK cyclino-dépendantes.
- GC78965ACT001 hydrochlorideCAS: 1403357-80-1Purity: >98.00%
ACT001 (Dimethylaminomicheliolide; DMAMCL) hydrochloride is an orally active, blood-brain barrier-permeable anti-inflammatory and anti-tumor agent.
- GC79003WCY-8-67 TFAPurity: >99.00%
WCY-8-67 TFA is an orally active and selective USP5 inhibitor, with an IC 50 value of 1.33 μM.
- GC79104(Rac)-Chem-0199CAS: 122981-77-5Purity: >99.50%
(Rac)-Chem-0199 is the racemic mixture of Chem-0199.
- GC79141T7 Peptide TFAPurity: >98.00%
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor.
- GC79175AMPK activator 19CAS: 1273323-44-6Purity: >98%
AMPK activator 19 (Compound 57), alkene oxindole derivative, is an AMPK activator.
- GC79176ARUK2010489Purity: >96.50%
ARUK2010489 (Compound 23) is a potent, selective and brain-penetrant NUAK1 inhibitor with a pIC 50 of 8.7.
- GC79177AMPK activator 18CAS: 1364692-88-5Purity: >98.00%
AMPK activator 18 is a potent allosteric activator of AMPK complexes containing the β2 isoform.
- GC79228Peptide R54 acetatePurity: >99.50%
Peptide R54 acetate (Pep R54 acetate) is a CXCR4 antagonist.
| Catalog No. | Product Name | CAS No. | Purity | Structure |
|---|---|---|---|---|
| GC73992 | KTC1101 | 2764833-47-6 | >98.00% | |
KTC1101 est un inhibiteur de pan-PI3K actif par voie orale. | ||||
| GC74012 | MTX-531 | 2791417-66-6 | >99.00% | |
MTX-531 est un médicament oral qui inhibe l'EGFR (IC50 de 14,7 nm) et PI3K (IC50 de 6,4, 233, 8,3 et 1,1 nm pour pi3kα, pi3kβ, pi3kγ et pi3kδ, respectivement) avec des effets antitumoraux. | ||||
| GC74025 | PIKfyve-IN-3 | - | >99.00% | |
PIKfyve-IN-3 (composé L22) a une interaction significative avec la kinase pikfyve avec une valeur de KD de 0,47 nm. | ||||
| GC74026 | DNA-PK-IN-12 | 2792146-91-7 | >99.00% | |
DNA-PK-IN-12 (composé 31t) est un inhibiteur actif de l'ADN - PK par voie orale avec une CI50 de 0,1 nm. | ||||
| GC74029 | ASCT2-IN-1 | 3032651-18-3 | >98.00% | |
ASCT2-IN-1 (composé 20k) est un inhibiteur d’asct2 avec des valeurs de ci50 de 5,6 μM et 3,5 μM dans les cellules A549 et HEK293, respectivement. | ||||
| GC74030 | ASCT2-IN-2 | - | >99.00% | |
ASCT2-IN-2 (composé 25e) est un inhibiteur d’asct2 avec une ci50 de 5,14 μM. | ||||
| GC74044 | ARM165 | - | >99.00% | |
ARM165 est une molécule hétérobifonctionnelle. | ||||
| GC74094 | Leniolisib-d5 | - | >98.00% | |
Leniolisib-d5 est un Leniolisib étiqueté deutérated. | ||||
| GC74261 | (R)-(+)-O-Demethylbuchenavianine | 1364123-68-1 | >98.00% | |
(R)-(+)-O-Demethylbuchenavianine est un inhibiteur des kinases CDK cyclino-dépendantes. | ||||
| GC74689 | WRX606 | 899937-47-4 | >95.00% | |
WRX606 est un inhibiteur du complexe mTOR 1 (mtorc1). | ||||
| GC78798 | NN3201 | - | >99.00% | |
NN3201 is a c-Kit -targeting antibody-drug conjugate ( ADC ) with high affinity ( K D = 0.19 pM). | ||||
| GC78965 | ACT001 hydrochloride | 1403357-80-1 | >98.00% | |
ACT001 (Dimethylaminomicheliolide; DMAMCL) hydrochloride is an orally active, blood-brain barrier-permeable anti-inflammatory and anti-tumor agent. | ||||
| GC78981 | HBS-101 | - | >99.50% | |
HBS-101 is a selectively, orally active, brain-penetrant, Midkine (MDK) inhibitor ( K D = 38.4 nM). | ||||
| GC79003 | WCY-8-67 TFA | - | >99.00% | |
WCY-8-67 TFA is an orally active and selective USP5 inhibitor, with an IC 50 value of 1.33 μM. | ||||
| GC79077 | DDO-6600 | 2640292-37-9 | >98.00% | |
DDO-6600 is a covalent Hsp90 inhibitor. | ||||
| GC79104 | (Rac)-Chem-0199 | 122981-77-5 | >99.50% | |
(Rac)-Chem-0199 is the racemic mixture of Chem-0199. | ||||
| GC79108 | AP4-43 | - | >99.50% | |
AP4-43 is an orally active CLK1, CLK4, PI3K, DDR1, EGFR and NEK4 inhibitor. | ||||
| GC79111 | CK2-TN03 | 313226-24-3 | >98.00% | |
CK2-TN03 is an ATP-competitive casein kinase 2 ( CK2 ) inhibitor, with an IC 50 of 165 nM and a K i of 20 nM. | ||||
| GC79117 | 8012–3246 | 421586-94-9 | >99.50% | |
8012-3246 is a selective PLK2 inhibitor with an IC 50 of 774.5 nM. | ||||
| GC79141 | T7 Peptide TFA | - | >98.00% | |
T7 Peptide TFA is a protein synthesis inhibitor and anti-angiogenic agent, with a K d of 10 nM for human transferrin receptor. | ||||
| GC79175 | AMPK activator 19 | 1273323-44-6 | >98% | |
AMPK activator 19 (Compound 57), alkene oxindole derivative, is an AMPK activator. | ||||
| GC79176 | ARUK2010489 | - | >96.50% | |
ARUK2010489 (Compound 23) is a potent, selective and brain-penetrant NUAK1 inhibitor with a pIC 50 of 8.7. | ||||
| GC79177 | AMPK activator 18 | 1364692-88-5 | >98.00% | |
AMPK activator 18 is a potent allosteric activator of AMPK complexes containing the β2 isoform. | ||||
| GC79228 | Peptide R54 acetate | - | >99.50% | |
Peptide R54 acetate (Pep R54 acetate) is a CXCR4 antagonist. | ||||