GLPBio

(Z)-Capsaicin

Catalog No.: GC35010Purity:>99.50%
(Z)-Capsaicin is the cis isomer of capsaicin, acts as an orally active TRPV1 agonist, and is used in the research of neuropathic pain.

Products are for research use only. Not for human use. We do not sell to patients.


(Z)-Capsaicin
Cas No.: 25775-90-0
10mM (in 1mL DMSO)In Stock
$61.00
1
10mgIn Stock
$56.00
1
50mgIn Stock
$176.00
1

Citations

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    618, 1017–1023 (2023)
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    610, 366–372 (2022)
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    Cell
    187(9):2288-2304 (2024)
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    183(7):1867-1883 (2020)
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Description

(Z)-Capsaicin is the cis isomer of capsaicin, acts as an orally active TRPV1 agonist, and is used in the research of neuropathic pain. TRPV1 receptor[1]

(Z)-Capsaicin is the cis isomer of capsaicin, acting as a TRPV1 agonist. (Z)-Capsaicin may also blocks the neruonal calcium channel[1].

(Z)-Capsaicin (Zucapsaicin) significantly attenuates nociceptive behavior after oral administration in rats. (Z)-Capsaicin is also tolerated in the primary or recurrent experimental genital herpes simplex virus infection in guinea pigs[1].

[1]. Bourne N, et al. Civamide (cis-capsaicin) for treatment of primary or recurrent experimental genital herpes. Antimicrob Agents Chemother. 1999 Nov;43(11):2685-8.

Product Documents

Purity:>99.50%Appearance:A solid

Chemical Properties

CAS No.
25775-90-0
SMILES
CC(C)/C=C\CCCCC(NCC1=CC=C(O)C(OC)=C1)=O
Molecular Formula
C18H27NO3
Molecular Weight
305.41
Solubility
DMSO: ≥ 125 mg/mL (409.29 mM)
Storage
Store at -20°C,protect from light
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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