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Amicarbazone

Catalog No.GC35317 Copy One-Click Copy Product Info

Amicarbazone(BAY-MKH3586; BAY314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); herbicide with a broad spectrum of weed control.

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Amicarbazone Chemical Structure

Cas No.: 129909-90-6

Size Price Stock Qty
10mg
$37.00
In stock
100mg
$149.00
In stock

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Sample solution is provided at 25 µL, 10mM.



Description of Amicarbazone

Amicarbazone(BAY-MKH3586; BAY314666) is a potent inhibitor of photosynthetic electron transport via binding to the Qb domain of photosystem II (PSII); herbicide with a broad spectrum of weed control.IC50 value:Target: PSII inhibitorThe phenotypic responses of sensitive plants exposed to amicarbazone include chlorosis, stunted growth, tissue necrosis, and death. Its efficacy as both a foliar- and root-applied herbicide suggests that absorption and translocation of this compound is very rapid. As a result, its efficacy is susceptible to the most common form of resistance to PSII inhibitors. Nonetheless, amicarbazone has a good selectivity profile and is a more potent herbicide than atrazine, which enables its use at lower rates than those of traditional photosynthetic inhibitors.

[1]. Franck E. Dayan, et al. Amicarbazone, a New Photosystem II Inhibitor. ed Science 57(6):579-583. 2009

Chemical Properties of Amicarbazone

Cas No. 129909-90-6 SDF
Canonical SMILES O=C(N1N=C(C(C)C)N(N)C1=O)NC(C)(C)C
Formula C10H19N5O2 M.Wt 241.29
Solubility Water: 1 mg/mL (4.14 mM; ultrasonic and heat to 50°C) Storage Store at -20°C
General tips Please select the appropriate solvent to prepare the stock solution according to the solubility of the product in different solvents; once the solution is prepared, please store it in separate packages to avoid product failure caused by repeated freezing and thawing.Storage method and period of the stock solution: When stored at -80°C, please use it within 6 months; when stored at -20°C, please use it within 1 month.
To increase solubility, heat the tube to 37°C and then oscillate in an ultrasonic bath for some time.
Shipping Condition Evaluation sample solution: shipped with blue ice. All other sizes available: with RT, or with Blue Ice upon request.

Complete Stock Solution Preparation Table of Amicarbazone

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1 mg 5 mg 10 mg
1 mM 4.1444 mL 20.722 mL 41.4439 mL
5 mM 828.9 μL 4.1444 mL 8.2888 mL
10 mM 414.4 μL 2.0722 mL 4.1444 mL
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In vivo Formulation Calculator (Clear solution) of Amicarbazone

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Method for preparing DMSO master liquid: mg drug pre-dissolved in μL DMSO ( Master liquid concentration mg/mL, Please contact us first if the concentration exceeds the DMSO solubility of the batch of drug. )

Method for preparing in vivo formulation: Take μL DMSO master liquid, next addμL PEG300, mix and clarify, next addμL Tween 80, mix and clarify, next add μL saline, mix and clarify.

Method for preparing in vivo formulation: Take μL DMSO master liquid, next add μL Corn oil, mix and clarify.

Note: 1. Please make sure the liquid is clear before adding the next solvent.
2. Be sure to add the solvent(s) in order. You must ensure that the solution obtained, in the previous addition, is a clear solution before proceeding to add the next solvent. Physical methods such as vortex, ultrasound or hot water bath can be used to aid dissolving.
3. All of the above co-solvents are available for purchase on the GlpBio website.

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Average Rating: 5 ★★★★★ (Based on Reviews and 10 reference(s) in Google Scholar.)

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