GLPBio

Amotosalen hydrochloride

Catalog No.: GC35326Purity:>98.00%Synonyms: S-59
COASDSData Sheet
Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens.

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Amotosalen hydrochloride
Cas No.: 161262-45-9
10mM (in 1mL DMSO)In Stock
$396.00
1
1mgIn Stock
$164.00
1
5mgIn Stock
$360.00
1
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Description

Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens[1].

When activated by light, Amotosalen binds to the nucleic acid of the pathogen and prevents replication. Light-activated Amotosalen binds and permanently crosslinks DNA, preventing replication and thus stopping proliferation of donor T cells[1].

[1]. Amotosalen: Allogeneic Cellular Immunotherapies system, INTERCEPT Plasma System, INTERCEPT Platelet System, S 59. BioDrugs. 2003;17(1):66-8.

Product Documents

Purity:>98.00%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
161262-45-9
Synonyms
S-59
SMILES
NCCOCC(C1=CC(C(C)=C2)=C3OC2=O)=C(C)OC1=C3C.[H]Cl.[H]Cl
Molecular Formula
C17H21Cl2NO4
Molecular Weight
374.26
Solubility
DMSO : 7.14 mg/mL (21.14 mM; Need ultrasonic)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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