GLPBio

Methotrexate metabolite

Catalog No.: GC36589Purity:>98.00%Synonyms: DAMPA
Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate.

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Methotrexate metabolite
Cas No.: 19741-14-1
10mM (in 1mL DMSO)In Stock
$19.00
1
5mgIn Stock
$17.00
1
10mgIn Stock
$27.00
1
25mgIn Stock
$56.00
1
50mgIn Stock
$90.00
1
100mgIn Stock
$133.00
1
200mgIn Stock
$197.00
1

Citations

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Description

Methotrexate metabolite (DAMPA), the active metabolite of Methotrexate. Methotrexate is a folic acid antagonist that is widely used as an immunosuppressant and chemotherapeutic agent[1].

[1]. Schofield RC, et al. Development and validation of a turbulent flow chromatography and tandem mass spectrometry method for the quantitation of methotrexate and its metabolites 7-hydroxy methotrexate and DAMPA in serum. J Chromatogr B Analyt Technol Biomed Life Sci. 2015 Oct 1;1002:169-75.

Product Documents

Purity:>98.00%Appearance:A solid

Chemical Properties

CAS No.
19741-14-1
Synonyms
DAMPA
SMILES
O=C(O)C1=CC=C(N(CC2=NC3=C(N)N=C(N)N=C3N=C2)C)C=C1
Molecular Formula
C15H15N7O2
Molecular Weight
325.33
Solubility
DMSO : 5 mg/mL (15.37 mM; ultrasonic and warming and heat to 60°C)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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