GLPBio

MSDC-0602

Catalog No.: GC36658Purity:>98.50%Synonyms: MSDC-0602
COASDSData Sheet
MSDC-0602 (MSDC-0602), a PPARγ-sparing thiazolidinedione (TZD), interacts with the mitochondrial pyruvate carrier (MPC) and inhibits its activity and has the potential for type 2 diabetes study with reducing risk of PPARγ-mediated side effects.

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MSDC-0602
Cas No.: 1133819-87-0
10mM (in 1mL DMSO)In Stock
$59.00
1
5mgIn Stock
$54.00
1
10mgIn Stock
$81.00
1
50mgIn Stock
$284.00
1
100mgIn Stock
$454.00
1
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Description

MSDC-0602, a PPARγ-sparing thiazolidinedione (TZD), interacts with the mitochondrial pyruvate carrier (MPC) and inhibits its activity and are effective for treatment of type 2 diabetes with reducing risk of PPARγ-mediated side effects[1][2].

[1]. Chen Z, et al. Resistance and metabolic derangements in obese mice are ameliorated by a novel peroxisome proliferator-activated receptor γ-sparing thiazolidinedione. J Biol Chem. 2012 Jul 6;287(28):23537-48. [2]. Vigueira PA, et al. The beneficial metabolic effects of sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism. Exp Physiol. 2017 Aug 1;102(8):985-999.

Product Documents

Purity:>98.50%Appearance:A solid
COASDSData Sheet

Chemical Properties

CAS No.
1133819-87-0
Synonyms
MSDC-0602
SMILES
O=C1C(SC(N1)=O)CC2=CC=C(OCC(C3=CC(OC)=CC=C3)=O)C=C2
Molecular Formula
C19H17NO5S
Molecular Weight
371.41
Solubility
DMSO: 125 mg/mL (336.56 mM); Water: < 0.1 mg/mL (insoluble)
Storage
Store at -20°C
General tips
Select a suitable solvent according to the product solubility data. Once prepared, aliquot the stock solution to avoid repeated freeze-thaw cycles.
Use stock solutions within 6 months when stored at -80°C or within 1 month when stored at -20°C.
To improve solubility, warm the tube to 37°C and sonicate it for an appropriate period.
Shipping Condition
Evaluation samples are shipped with blue ice. Other available sizes are shipped at room temperature or with blue ice upon request.

CalculatorsMolarity / Dilution / Molecular Weight / Unit Conversion / In Vivo Formulation / Solubility

g/mol

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