Ac-VDVAD-pNA (trifluoroacetate salt) (Synonyms: Ac-Val-Asp-Val-Ala-Asp-pNA, Caspase-2 Chromogenic Substrate, acetyl-Val-Asp-Val-Ala-Asp-p-nitroanilide, acetyl-VDVAD-p-nitroanilide) |
| Catalog No.GC42716 |
Ac-VDVAD-pNA is a colorimetric substrate for caspase-2.
Products are for research use only. Not for human use. We do not sell to patients.
Sample solution is provided at 25 µL, 10mM.
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Ac-VDVAD-pNA is a colorimetric substrate for caspase-2. Caspase-2 binds to and cleaves the Val-Asp-Val-Ala-Asp (VDVAD) peptide sequence to release p-nitroanilide (pNA), which can be quantified by colorimetric detection at 405 nm as a measure of caspase-2 activity. Ac-VDVAD-pNA can also be cleaved, with lower efficiency, by caspase-3 and -7.
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Average Rating: 5 (Based on Reviews and 14 reference(s) in Google Scholar.)
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